IL166591A0 - Preparation of aztreonam - Google Patents
Preparation of aztreonamInfo
- Publication number
- IL166591A0 IL166591A0 IL16659105A IL16659105A IL166591A0 IL 166591 A0 IL166591 A0 IL 166591A0 IL 16659105 A IL16659105 A IL 16659105A IL 16659105 A IL16659105 A IL 16659105A IL 166591 A0 IL166591 A0 IL 166591A0
- Authority
- IL
- Israel
- Prior art keywords
- aztreonam
- preparation
- Prior art date
Links
- WZPBZJONDBGPKJ-UHFFFAOYSA-N Antibiotic SQ 26917 Natural products O=C1N(S(O)(=O)=O)C(C)C1NC(=O)C(=NOC(C)(C)C(O)=O)C1=CSC(N)=N1 WZPBZJONDBGPKJ-UHFFFAOYSA-N 0.000 title 1
- WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 title 1
- 229960003644 aztreonam Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40069902P | 2002-08-05 | 2002-08-05 | |
| US40174902P | 2002-08-08 | 2002-08-08 | |
| PCT/US2003/024593 WO2004013133A1 (en) | 2002-08-05 | 2003-08-05 | Preparation of aztreonam |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL166591A0 true IL166591A0 (en) | 2006-01-15 |
Family
ID=31498630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16659105A IL166591A0 (en) | 2002-08-05 | 2005-01-31 | Preparation of aztreonam |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7145017B2 (de) |
| EP (1) | EP1527072A1 (de) |
| JP (1) | JP2006514608A (de) |
| KR (1) | KR100687001B1 (de) |
| CN (1) | CN1681812A (de) |
| AU (1) | AU2003265373A1 (de) |
| IL (1) | IL166591A0 (de) |
| MX (1) | MXPA05001486A (de) |
| WO (1) | WO2004013133A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004103999A1 (en) | 2003-05-15 | 2004-12-02 | TEVA Gyógyszergyár Részvénytársaság | AZTREONAM β POLYMORPH WITH VERY LOW RESIDUAL SOLVENT CONTENT |
| WO2005005424A1 (en) * | 2003-07-02 | 2005-01-20 | TEVA Gyógyszergyár Részvénytársaság | Aztreonam l-lysine and methods for the preparation thereof |
| US7601832B2 (en) | 2005-05-09 | 2009-10-13 | Sicor, Inc. | Process for making aztreonam |
| WO2007083187A2 (en) * | 2006-01-16 | 2007-07-26 | Orchid Chemicals & Pharmaceuticals Limited | An improved process for the preparation of monobactam antibiotic |
| CN101412715B (zh) * | 2008-12-16 | 2010-04-14 | 海南百那医药发展有限公司 | 一种氨曲南化合物及其制法 |
| CN102127068B (zh) * | 2010-12-31 | 2012-08-29 | 山西普德药业股份有限公司 | 一种合成氨曲南化合物的方法 |
| CN102311431B (zh) * | 2011-08-30 | 2014-12-10 | 海南海药股份有限公司 | 一种制备无水β-氨曲南的方法 |
| CN105017241B (zh) * | 2015-06-24 | 2018-03-06 | 山东罗欣药业集团股份有限公司 | 一种氨曲南化合物及其制剂 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923998A (en) | 1977-03-14 | 1990-05-08 | Fujisawa Pharmaceutical Company, Ltd. | Cephem and cepham compounds and processes for preparation thereof |
| US4775670A (en) | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
| US4529698A (en) | 1981-01-19 | 1985-07-16 | E. R. Squibb & Sons, Inc. | Process for preparing a 2-oxo-1-azetidinesulfonic acid salt |
| CA1181075A (en) | 1981-07-13 | 1985-01-15 | David M. Floyd | CRYSTALLINE ANHYDROUS FORM OF [3-S-[3.alpha.(Z),4 .beta.]]-3-[[(2-AMINO-4-THIAZOLYL) [(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL] AMINO]-4-METHYL-2-OXO-1-AZETIDINESULFONIC ACID |
| US4946838A (en) | 1981-07-13 | 1990-08-07 | E. R. Squibb & Sons, Inc. | Crystalline anhydrous aztreonam |
| US4652651A (en) | 1983-05-31 | 1987-03-24 | Hoffmann-La Roche Inc. | Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage |
| US4826973A (en) | 1984-07-20 | 1989-05-02 | E. R. Squibb & Sons, Inc. | Delta form of aztreonam and preparation thereof |
| CA1339136C (en) | 1987-07-01 | 1997-07-29 | Sailesh Amilal Varia | Amorphous form of aztreonam |
| US5254681A (en) * | 1989-08-02 | 1993-10-19 | Consiglio Nazionale Delle Ricerche | Process for preparing monobactames and their intermediate product |
| US5194604A (en) * | 1990-06-29 | 1993-03-16 | E. R. Squibb & Sons, Inc. | Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains |
| PL165700B1 (pl) | 1991-10-15 | 1995-01-31 | Pan | Sposób wytwarzania kwasu 32/2-amtnotiazoiilo-4/-2/1 -t-butoksykarbonylo- 1 -metyloetoksylmino/octowego |
| US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| US6660249B2 (en) | 2000-12-27 | 2003-12-09 | Salus Pharma, Inc. | Inhalable dry powder aztreonam for treatment and prevention of pulmonary bacterial infections |
| CN1545514A (zh) | 2001-08-27 | 2004-11-10 | 阿拉宾度药业有限公司 | β型晶体无水氨曲南的生产方法 |
| WO2004052333A1 (en) | 2002-12-11 | 2004-06-24 | Pari Gmbh | Pharmaceutical compositions for the pulmonary delivery of aztreonam |
| WO2004103999A1 (en) | 2003-05-15 | 2004-12-02 | TEVA Gyógyszergyár Részvénytársaság | AZTREONAM β POLYMORPH WITH VERY LOW RESIDUAL SOLVENT CONTENT |
| WO2005005424A1 (en) | 2003-07-02 | 2005-01-20 | TEVA Gyógyszergyár Részvénytársaság | Aztreonam l-lysine and methods for the preparation thereof |
-
2003
- 2003-08-05 EP EP03767242A patent/EP1527072A1/de not_active Withdrawn
- 2003-08-05 CN CNA038187159A patent/CN1681812A/zh active Pending
- 2003-08-05 JP JP2004526053A patent/JP2006514608A/ja active Pending
- 2003-08-05 MX MXPA05001486A patent/MXPA05001486A/es active IP Right Grant
- 2003-08-05 US US10/635,659 patent/US7145017B2/en not_active Expired - Fee Related
- 2003-08-05 KR KR1020057001992A patent/KR100687001B1/ko not_active Expired - Fee Related
- 2003-08-05 AU AU2003265373A patent/AU2003265373A1/en not_active Abandoned
- 2003-08-05 WO PCT/US2003/024593 patent/WO2004013133A1/en not_active Ceased
-
2005
- 2005-01-31 IL IL16659105A patent/IL166591A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003265373A1 (en) | 2004-02-23 |
| US7145017B2 (en) | 2006-12-05 |
| WO2004013133A1 (en) | 2004-02-12 |
| MXPA05001486A (es) | 2006-05-25 |
| KR100687001B1 (ko) | 2007-02-27 |
| US20040063682A1 (en) | 2004-04-01 |
| KR20050033647A (ko) | 2005-04-12 |
| JP2006514608A (ja) | 2006-05-11 |
| CN1681812A (zh) | 2005-10-12 |
| EP1527072A1 (de) | 2005-05-04 |
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