IL162868A0 - Depot medicament, carrier materials for depot medicaments, and method for the production thereof - Google Patents

Depot medicament, carrier materials for depot medicaments, and method for the production thereof

Info

Publication number
IL162868A0
IL162868A0 IL16286803A IL16286803A IL162868A0 IL 162868 A0 IL162868 A0 IL 162868A0 IL 16286803 A IL16286803 A IL 16286803A IL 16286803 A IL16286803 A IL 16286803A IL 162868 A0 IL162868 A0 IL 162868A0
Authority
IL
Israel
Prior art keywords
depot
carrier
carrier materials
medicament
medicaments
Prior art date
Application number
IL16286803A
Original Assignee
Stoess & Co Gelatine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stoess & Co Gelatine filed Critical Stoess & Co Gelatine
Publication of IL162868A0 publication Critical patent/IL162868A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Biological Treatment Of Waste Water (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Detergent Compositions (AREA)

Abstract

Disclosed are a depot medicament containing a pharmacological agent and a carrier, particularly a depot medicament to be administered parenterally, carrier materials for depot medicaments, and a method for producing said carrier materials. A set amount of an agent is released over time while the agent is preserved in its pharmacologically effective form. The carrier is produced by using a carrier material comprising a carrier polymer formed by a polypeptide and a biodegradable polyester which is covalently linked thereto.
IL16286803A 2002-02-16 2003-01-24 Depot medicament, carrier materials for depot medicaments, and method for the production thereof IL162868A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10206517A DE10206517A1 (en) 2002-02-16 2002-02-16 Depot medicinal products, carrier materials for depot medicinal products and processes for their production
PCT/EP2003/000725 WO2003068192A1 (en) 2002-02-16 2003-01-24 Depot medicament, carrier materials for depot medicaments, and method for the production thereof

Publications (1)

Publication Number Publication Date
IL162868A0 true IL162868A0 (en) 2005-11-20

Family

ID=27674694

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16286803A IL162868A0 (en) 2002-02-16 2003-01-24 Depot medicament, carrier materials for depot medicaments, and method for the production thereof
IL162868A IL162868A (en) 2002-02-16 2004-07-05 Depot medicament, carrier materials for depot medicaments and method for the production thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL162868A IL162868A (en) 2002-02-16 2004-07-05 Depot medicament, carrier materials for depot medicaments and method for the production thereof

Country Status (17)

Country Link
EP (1) EP1474110B1 (en)
AT (1) ATE369123T1 (en)
AU (1) AU2003210181A1 (en)
BR (1) BR0307675A (en)
DE (2) DE10206517A1 (en)
DK (1) DK1474110T3 (en)
EA (1) EA006988B1 (en)
ES (1) ES2289304T3 (en)
HU (1) HUP0500119A3 (en)
IL (2) IL162868A0 (en)
MX (1) MXPA04006982A (en)
NO (1) NO20043860L (en)
NZ (1) NZ533103A (en)
PL (1) PL371785A1 (en)
PT (1) PT1474110E (en)
WO (1) WO2003068192A1 (en)
ZA (1) ZA200403979B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20060682A1 (en) * 2006-12-19 2008-06-20 Sicit Chemitech S P A NEW BIODEGRADABLE POLYMER DERIVATIVES
DE102007011606A1 (en) 2007-03-02 2008-09-04 Carl Freudenberg Kg Fiber-tangled structure useful as cell settling material, wound covering, medical implant and carriers for pharmaceutical active substance and for producing depot medicament, comprises fibers made of partially interlaced gelatin material

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2046830C (en) * 1990-07-19 1999-12-14 Patrick P. Deluca Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
GB9211268D0 (en) * 1992-05-28 1992-07-15 Ici Plc Salts of basic peptides with carboxyterminated polyesters
DK0814778T3 (en) * 1995-03-10 2001-09-17 Roche Diagnostics Gmbh Polypeptide-containing pharmaceutical administration forms in the form of microparticles and their method of preparation
DE19813174A1 (en) * 1998-03-25 1999-05-27 Schering Ag Gas-filled microparticles, used for administering biologically active substances
CA2370357C (en) * 1999-04-16 2007-04-10 Wm. Marsh Rice University Poly(propylene fumarate) cross linked with poly(ethylene glycol)

Also Published As

Publication number Publication date
WO2003068192A1 (en) 2003-08-21
EP1474110B1 (en) 2007-08-08
BR0307675A (en) 2005-01-11
ZA200403979B (en) 2004-11-29
PT1474110E (en) 2007-10-01
EA200401012A1 (en) 2005-04-28
HUP0500119A3 (en) 2008-04-28
ES2289304T3 (en) 2008-02-01
EP1474110A1 (en) 2004-11-10
ATE369123T1 (en) 2007-08-15
IL162868A (en) 2008-03-20
MXPA04006982A (en) 2004-11-10
DE10206517A1 (en) 2003-09-04
EA006988B1 (en) 2006-06-30
NO20043860L (en) 2004-09-15
DE50307874D1 (en) 2007-09-20
NZ533103A (en) 2007-04-27
HUP0500119A2 (en) 2005-07-28
AU2003210181A1 (en) 2003-09-04
DK1474110T3 (en) 2007-12-10
PL371785A1 (en) 2005-06-27

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Legal Events

Date Code Title Description
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KB Patent renewed
KB Patent renewed