IL162618A0 - Liquid composition of modified factor vii polypeptides - Google Patents

Liquid composition of modified factor vii polypeptides

Info

Publication number
IL162618A0
IL162618A0 IL16261802A IL16261802A IL162618A0 IL 162618 A0 IL162618 A0 IL 162618A0 IL 16261802 A IL16261802 A IL 16261802A IL 16261802 A IL16261802 A IL 16261802A IL 162618 A0 IL162618 A0 IL 162618A0
Authority
IL
Israel
Prior art keywords
liquid composition
factor vii
modified factor
vii polypeptides
polypeptides
Prior art date
Application number
IL16261802A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL162618A0 publication Critical patent/IL162618A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL16261802A 2001-12-21 2002-12-20 Liquid composition of modified factor vii polypeptides IL162618A0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200101948 2001-12-21
DKPA200101949 2001-12-21
US34688802P 2002-01-07 2002-01-07
US34639902P 2002-01-07 2002-01-07
PCT/DK2002/000894 WO2003055511A1 (en) 2001-12-21 2002-12-20 Liquid composition of modified factor vii polypeptides

Publications (1)

Publication Number Publication Date
IL162618A0 true IL162618A0 (en) 2005-11-20

Family

ID=27439852

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16261802A IL162618A0 (en) 2001-12-21 2002-12-20 Liquid composition of modified factor vii polypeptides

Country Status (12)

Country Link
US (1) US20040043933A1 (xx)
EP (1) EP1458407A1 (xx)
JP (1) JP2005530682A (xx)
CN (1) CN1606452A (xx)
AU (1) AU2002351755A1 (xx)
BR (1) BR0215218A (xx)
CA (1) CA2470313A1 (xx)
HU (1) HUP0402303A2 (xx)
IL (1) IL162618A0 (xx)
PL (1) PL370656A1 (xx)
RU (1) RU2004122430A (xx)
WO (1) WO2003055511A1 (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2445811A1 (en) * 2001-05-02 2002-11-07 Novo Nordisk A/S Modified fvii in treatment of ards
IL162239A0 (en) * 2001-12-21 2005-11-20 Novo Nordisk Healthcare Ag Liquid composition of factor vii polypeptides
KR20040065278A (ko) * 2001-12-21 2004-07-21 노보 노르디스크 에이/에스 변경된 인자 ⅶ 폴리펩티드의 액체 조성물
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
EP2283856B1 (en) 2002-06-21 2017-09-20 Novo Nordisk Health Care AG Stabilised solid compositions of factor VIIa polypeptides
MXPA05009914A (es) * 2003-03-18 2006-01-09 Novo Nordisk Healthcare Ag Composiciones farmaceuticas acuosas, liquidas de polipeptidos del factor vii.
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
CA2525224A1 (en) * 2003-05-23 2004-12-02 Michael Bech Jensen Protein stabilization in solution
ATE547114T1 (de) 2003-06-25 2012-03-15 Novo Nordisk Healthcare Ag Flüssige zusammensetzungen von factor vii polypeptiden
ES2335994T3 (es) * 2003-07-01 2010-04-07 Novo Nordisk Health Care Ag Composicion farmaceutica liquida, acuosa de polipeptidos factor vii.
ES2574581T3 (es) * 2003-08-14 2016-06-20 Novo Nordisk Health Care Ag Composición farmacéutica líquida acuosa de polipéptidos de tipo Factor VII
WO2005023308A1 (en) * 2003-09-05 2005-03-17 Maxygen Holdings Ltd. Formulations of vitamin k-dependent polypeptides and sulfoalkyl ether cycloextrins
EP2298287B1 (en) * 2003-12-19 2018-04-11 Novo Nordisk Health Care AG Stabilised compositions of factor VII polypeptides
AU2005237523A1 (en) 2004-04-23 2005-11-10 Cydex Pharmaceuticals, Inc. DPI formulation containing sulfoalkyl ether cyclodextrin
RU2006138181A (ru) 2004-05-04 2008-06-10 Ново Нордиск Хелс Кеа Аг (Ch) О-связанные гликоформы полипептидов и способ их изготовления
US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
JP2006137678A (ja) * 2004-11-10 2006-06-01 Shionogi & Co Ltd インターロイキン−２組成物
EP1853926A2 (en) * 2005-02-16 2007-11-14 The Board Of Trustees Of The University Of Illinois Procoagulants based on metal-chelating lipids
EP1869082B1 (en) * 2005-03-04 2011-04-13 The Board Of Trustees Of The University Of Illinois Coagulation and fibrinolytic cascades modulator
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
WO2008127702A2 (en) * 2007-04-13 2008-10-23 Catalyst Biosciences, Inc. Modified factor vii polypetides and uses thereof
WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
TWI465247B (zh) 2008-04-11 2014-12-21 Catalyst Biosciences Inc 經修飾的因子ｖｉｉ多肽和其用途
PL2328601T3 (pl) * 2008-08-15 2020-07-13 Ironwood Pharmaceuticals, Inc. Formulacje zawierające linaklotyd do podawania doustnego
WO2011017502A2 (en) * 2009-08-06 2011-02-10 Ironwood Pharmaceuticals, Inc. Linaclotide-containing formulations for oral administration
UA108636C2 (xx) 2010-02-17 2015-05-25 Пептид
SI2603232T1 (sl) 2010-08-11 2020-03-31 Ironwood Pharmaceuticals, Inc. Stabilne formulacije linaklotida
JP6312592B2 (ja) 2011-08-17 2018-04-18 アイアンウッド ファーマシューティカルズ インコーポレイテッド 消化器疾患の治療
WO2014142102A1 (ja) 2013-03-12 2014-09-18 大日本住友製薬株式会社 液体水性組成物
CN107490675B (zh) * 2017-08-10 2019-02-12 迈克生物股份有限公司 一种免疫比浊试剂盒及检测方法
CN107490696A (zh) * 2017-08-10 2017-12-19 迈克生物股份有限公司 一种视黄醇结合蛋白检测试剂盒及检测方法
CN107490676B (zh) * 2017-08-10 2019-02-12 迈克生物股份有限公司 一种补体c3检测试剂盒及检测方法
CN107356764A (zh) * 2017-08-10 2017-11-17 迈克生物股份有限公司 一种载脂蛋白e检测试剂盒及检测方法
WO2021030787A1 (en) 2019-08-15 2021-02-18 Catalyst Biosciences, Inc. Modified factor vii polypeptides for subcutaneous administration and on-demand treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US5833982A (en) * 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation
US5925738A (en) * 1995-12-01 1999-07-20 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
US5770700A (en) * 1996-01-25 1998-06-23 Genetics Institute, Inc. Liquid factor IX formulations
US20010031721A1 (en) * 1999-05-05 2001-10-18 Chandra Webb Highly concentrated, lyophilized, and liquid factor IX formulations

Also Published As

Publication number Publication date
JP2005530682A (ja) 2005-10-13
AU2002351755A1 (en) 2003-07-15
RU2004122430A (ru) 2005-04-20
HUP0402303A2 (hu) 2005-01-28
EP1458407A1 (en) 2004-09-22
CA2470313A1 (en) 2003-07-10
BR0215218A (pt) 2004-11-16
PL370656A1 (en) 2005-05-30
US20040043933A1 (en) 2004-03-04
WO2003055511A1 (en) 2003-07-10
CN1606452A (zh) 2005-04-13

Similar Documents

Publication Publication Date Title
HUP0402315A3 (en) Liquid composition of factor vii polypeptides
IL162618A0 (en) Liquid composition of modified factor vii polypeptides
EG24078A (en) Liquid pharmaceutical composition
HUP0401116A3 (en) Stable liquid peticide compositions
IL158802A0 (en) Stable liquid formulations of antibodies
IL165608A0 (en) Stabilised solid compositions of factor VII polypeptides
GB0116825D0 (en) Determination of material parameters
GB0117879D0 (en) Storage of liquid compositions
AU2002358308A8 (en) Fluid mixture composition sensor
HUP0400976A3 (en) Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides
HK1063483A1 (en) Liquid detergent composition
AU2002255354A1 (en) Minoxidil-containing liquid composition
IL161544A0 (en) Pharmaceutical composition comprising factor vii polypeptides and factor v polypeptides
EP1365818A4 (en) COMPOSITION OF A POROUS ELEMENT FOR A BIOLOGICAL MATERIAL
EP1360964A4 (en) USE OF A GALANINE-LIKE PEPTID
IL156547A0 (en) Pharmaceutical composition containing citalopram
HUP0401959A3 (en) Pharmaceutical composition comprising factor vii polypeptides and pai-1 polypeptides
TW506438U (en) Improved structure of liquid container
TW522848U (en) Cottonbud containing liquid
AU2002340781A1 (en) Pharmaceutical composition comprising factor vii polypeptides and thrombomodulin polypeptides
AU2002311270A1 (en) Liquid composition
TW569752U (en) Improved structure of container
TW480984U (en) Improved structure of seasoner container
TW540341U (en) Structure improvement of container
GB0104667D0 (en) Spraying of liquids