IL158494A0 - A three-step method for producing paclitaxel - Google Patents

A three-step method for producing paclitaxel

Info

Publication number
IL158494A0
IL158494A0 IL15849402A IL15849402A IL158494A0 IL 158494 A0 IL158494 A0 IL 158494A0 IL 15849402 A IL15849402 A IL 15849402A IL 15849402 A IL15849402 A IL 15849402A IL 158494 A0 IL158494 A0 IL 158494A0
Authority
IL
Israel
Prior art keywords
step method
producing paclitaxel
paclitaxel
producing
Prior art date
Application number
IL15849402A
Other languages
English (en)
Original Assignee
Napro Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Napro Biotherapeutics Inc filed Critical Napro Biotherapeutics Inc
Publication of IL158494A0 publication Critical patent/IL158494A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
IL15849402A 2001-04-25 2002-04-25 A three-step method for producing paclitaxel IL158494A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/843,235 US6452025B1 (en) 2001-04-25 2001-04-25 Three-step conversion of protected taxane ester to paclitaxel
PCT/US2002/013288 WO2002085879A1 (en) 2001-04-25 2002-04-25 Three-step conversion of protected taxane ester to paclitaxel

Publications (1)

Publication Number Publication Date
IL158494A0 true IL158494A0 (en) 2004-05-12

Family

ID=25289410

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15849402A IL158494A0 (en) 2001-04-25 2002-04-25 A three-step method for producing paclitaxel

Country Status (8)

Country Link
US (1) US6452025B1 (de)
EP (1) EP1389196A4 (de)
JP (1) JP2004535385A (de)
CA (1) CA2445250A1 (de)
IL (1) IL158494A0 (de)
NO (1) NO20034638L (de)
NZ (1) NZ531445A (de)
WO (1) WO2002085879A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1599457A4 (de) * 2003-02-04 2008-05-07 Natural Pharmaceuticals Inc Verfahren und zusammensetzung für die zubereitung einer verbindung mit einem im wesentlichen ringchlorierungsfreien benzoylierenden wirkstoff

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2629818B1 (fr) 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
USRE34277E (en) 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US4960790A (en) 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5015744A (en) 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
FR2658513B1 (fr) 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
FR2680506B1 (fr) 1991-08-19 1994-09-02 Rhone Poulenc Rorer Sa Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
FR2687150B1 (fr) 1992-02-07 1995-04-28 Rhone Poulenc Rorer Sa Procede de preparation de derives du taxane.
US5319112A (en) * 1992-08-18 1994-06-07 Virgnia Tech Intellectual Properties, Inc. Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol
EP1260507A1 (de) * 1993-02-05 2002-11-27 Bryn Mawr College Synthese von Taxol, Analogen und Zwischenverbindungen mit veränderlichen A-ring Seiten Ketten
US5684175A (en) 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
US5675025A (en) * 1995-06-07 1997-10-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
US5973170A (en) 1996-09-25 1999-10-26 Napro Biotherapuetics, Inc. C-7 metal alkoxides of baccatin III

Also Published As

Publication number Publication date
US6452025B1 (en) 2002-09-17
WO2002085879A1 (en) 2002-10-31
NZ531445A (en) 2004-06-25
NO20034638D0 (no) 2003-10-17
WO2002085879B1 (en) 2003-04-03
JP2004535385A (ja) 2004-11-25
CA2445250A1 (en) 2002-10-31
EP1389196A1 (de) 2004-02-18
EP1389196A4 (de) 2005-08-17
NO20034638L (no) 2003-12-02

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