IL157608A0 - New crystal forms of lamotrigine and processes for their preparations - Google Patents
New crystal forms of lamotrigine and processes for their preparationsInfo
- Publication number
- IL157608A0 IL157608A0 IL15760802A IL15760802A IL157608A0 IL 157608 A0 IL157608 A0 IL 157608A0 IL 15760802 A IL15760802 A IL 15760802A IL 15760802 A IL15760802 A IL 15760802A IL 157608 A0 IL157608 A0 IL 157608A0
- Authority
- IL
- Israel
- Prior art keywords
- lamotrigine
- preparations
- processes
- crystal forms
- new crystal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27168801P | 2001-02-27 | 2001-02-27 | |
PCT/US2002/006160 WO2002068398A1 (en) | 2001-02-27 | 2002-02-27 | New crystal forms of lamotrigine and processes for their preparations |
Publications (1)
Publication Number | Publication Date |
---|---|
IL157608A0 true IL157608A0 (en) | 2004-03-28 |
Family
ID=23036634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15760802A IL157608A0 (en) | 2001-02-27 | 2002-02-27 | New crystal forms of lamotrigine and processes for their preparations |
Country Status (6)
Country | Link |
---|---|
US (3) | US6861426B2 (xx) |
EP (1) | EP1390355A4 (xx) |
JP (1) | JP2004526714A (xx) |
CA (1) | CA2439468A1 (xx) |
IL (1) | IL157608A0 (xx) |
WO (1) | WO2002068398A1 (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL157608A0 (en) * | 2001-02-27 | 2004-03-28 | Teva Pharma | New crystal forms of lamotrigine and processes for their preparations |
AU2003234240A1 (en) * | 2002-04-23 | 2003-11-10 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing lamotrigine particles of defined morphology |
AU2003217437A1 (en) * | 2003-03-17 | 2004-10-11 | Hetero Drugs Limited | Novel crystalline forms of lamotrigine |
AU2003230193A1 (en) | 2003-03-27 | 2004-10-18 | Hetero Drugs Limited | Novel crystalline forms of candesartan cilexetil |
GB2395483A (en) * | 2003-07-03 | 2004-05-26 | Jubilant Organosys Ltd | Crystalline lamotrigine and its monohydrate |
US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
US20120142919A1 (en) * | 2006-08-02 | 2012-06-07 | Medichem, S.A. | Method for synthesizing lamotrigine |
WO2009061513A1 (en) * | 2007-11-09 | 2009-05-14 | Thar Pharmaceuticals | Crystalline forms of lamotrigine |
CN113214177B (zh) * | 2021-04-16 | 2022-05-03 | 上海奥科达生物医药科技有限公司 | 一种拉莫三嗪水合物的晶体形式、其制备方法及包含其的组合物 |
CN115068422B (zh) * | 2022-08-19 | 2022-11-29 | 上海奥科达生物医药科技有限公司 | 一种拉莫三嗪湿混悬剂及其制备方法和应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR68380B (xx) * | 1979-06-01 | 1981-12-28 | Wellcome Found | |
EP0021120B1 (en) * | 1979-06-01 | 1983-04-06 | The Wellcome Foundation Limited | 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
ES8604019A1 (es) | 1985-04-15 | 1986-01-16 | Nippon Shinyaku Co Ltd | Un procedimiento para preparar polvo fino de 2,5-dicloroben-zoguanamina y sus sales |
GB8613183D0 (en) * | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
US5643591A (en) * | 1991-01-16 | 1997-07-01 | Fmc Corporation | Solid dosage forms |
GB9424766D0 (en) * | 1994-12-07 | 1995-02-08 | Wellcome Found | Pharmaceutical composition |
GB9426448D0 (en) * | 1994-12-30 | 1995-03-01 | Wellcome Found | Process |
GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
GB9518027D0 (en) * | 1995-09-05 | 1995-11-08 | Wellcome Found | Pharmacologically active compound |
US6525185B1 (en) * | 1998-05-07 | 2003-02-25 | Affymetrix, Inc. | Polymorphisms associated with hypertension |
CZ20011949A3 (cs) * | 1998-12-14 | 2001-09-12 | Torrent Pharmacauticals Ltd | Zlepšený způsob výroby 3,5-diamino-6-(2,3-dichlorfenyl)-1,2,4-triazinu |
EA005423B1 (ru) | 1999-09-24 | 2005-02-24 | Янссен Фармацевтика Н.В. | Противовирусные композиции |
US6639072B1 (en) * | 2000-01-03 | 2003-10-28 | Rpg Life Sciences Limited | Process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine |
WO2001094322A1 (en) * | 2000-06-08 | 2001-12-13 | Merck & Co., Inc. | 4-benzyl-2-hydroxy-1,4-oxazin-3-one and polymorphic forms thereof |
IL157608A0 (en) * | 2001-02-27 | 2004-03-28 | Teva Pharma | New crystal forms of lamotrigine and processes for their preparations |
US7049322B2 (en) * | 2002-02-21 | 2006-05-23 | Supergen, Inc. | Compositions and formulations of 9-nitrocamptothecin polymorphs and methods of use therefor |
ES2233227T1 (es) * | 2003-03-26 | 2005-06-16 | Teva Pharmaceutical Industries Ltd. | Procedimiento para la preparacion de ingredientes farmaceuticos activos con un area superficial especifica. |
-
2002
- 2002-02-27 IL IL15760802A patent/IL157608A0/xx unknown
- 2002-02-27 EP EP02706471A patent/EP1390355A4/en not_active Withdrawn
- 2002-02-27 JP JP2002567912A patent/JP2004526714A/ja active Pending
- 2002-02-27 US US10/086,157 patent/US6861426B2/en not_active Expired - Fee Related
- 2002-02-27 CA CA002439468A patent/CA2439468A1/en not_active Abandoned
- 2002-02-27 WO PCT/US2002/006160 patent/WO2002068398A1/en active Application Filing
-
2005
- 2005-01-31 US US11/045,355 patent/US7390807B2/en not_active Expired - Fee Related
-
2008
- 2008-01-30 US US12/012,183 patent/US20080139808A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030018030A1 (en) | 2003-01-23 |
US7390807B2 (en) | 2008-06-24 |
EP1390355A4 (en) | 2005-02-23 |
JP2004526714A (ja) | 2004-09-02 |
US20080139808A1 (en) | 2008-06-12 |
WO2002068398A9 (en) | 2002-11-21 |
WO2002068398A1 (en) | 2002-09-06 |
US6861426B2 (en) | 2005-03-01 |
EP1390355A2 (en) | 2004-02-25 |
CA2439468A1 (en) | 2002-09-06 |
US20050171107A1 (en) | 2005-08-04 |
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