IL156114A0 - Method and apparatus using a surface-selective nonlinear optical technique for detection of probe-target interactions - Google Patents

Method and apparatus using a surface-selective nonlinear optical technique for detection of probe-target interactions

Info

Publication number
IL156114A0
IL156114A0 IL15611401A IL15611401A IL156114A0 IL 156114 A0 IL156114 A0 IL 156114A0 IL 15611401 A IL15611401 A IL 15611401A IL 15611401 A IL15611401 A IL 15611401A IL 156114 A0 IL156114 A0 IL 156114A0
Authority
IL
Israel
Prior art keywords
probe
detection
nonlinear optical
optical technique
target interactions
Prior art date
Application number
IL15611401A
Original Assignee
Joshua S Salafsky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joshua S Salafsky filed Critical Joshua S Salafsky
Publication of IL156114A0 publication Critical patent/IL156114A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
IL15611401A 2000-11-29 2001-07-17 Method and apparatus using a surface-selective nonlinear optical technique for detection of probe-target interactions IL156114A0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25386200P 2000-11-29 2000-11-29
US26024901P 2001-01-08 2001-01-08
US26577501P 2001-02-01 2001-02-01
US27864101P 2001-03-27 2001-03-27
PCT/US2001/022411 WO2002044412A1 (en) 2000-11-29 2001-07-17 Method and apparatus using a surface-selective nonlinear optical technique for detection of probe-target interactions

Publications (1)

Publication Number Publication Date
IL156114A0 true IL156114A0 (en) 2003-12-23

Family

ID=27500490

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15611401A IL156114A0 (en) 2000-11-29 2001-07-17 Method and apparatus using a surface-selective nonlinear optical technique for detection of probe-target interactions

Country Status (5)

Country Link
EP (1) EP1346064A4 (en)
AU (1) AU2001278937A1 (en)
CA (1) CA2430430A1 (en)
IL (1) IL156114A0 (en)
WO (1) WO2002044412A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6953694B2 (en) 2000-12-06 2005-10-11 The Trustees Of Columbia University In The City Of New York Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces
US20030148391A1 (en) * 2002-01-24 2003-08-07 Salafsky Joshua S. Method using a nonlinear optical technique for detection of interactions involving a conformational change
US8088628B2 (en) 2002-09-30 2012-01-03 Intel Corporation Stimulated and coherent anti-stokes raman spectroscopic methods for the detection of molecules
US20040142484A1 (en) 2002-09-30 2004-07-22 Intel Corporation Spectroscopic analysis system and method
EP1549929B1 (en) * 2002-10-07 2010-12-08 The Secretary Of State For Defence A waveguide structure
JP4173746B2 (en) * 2003-02-12 2008-10-29 富士フイルム株式会社 measuring device
JP2004279040A (en) * 2003-03-12 2004-10-07 Toyobo Co Ltd Flow cell for measuring surface plasmon resonance
WO2005064333A1 (en) 2003-12-25 2005-07-14 National Institute Of Advanced Industrial Science And Technology Method of analyzing interaction between protein and sugar chain
JP3918040B2 (en) * 2004-03-03 2007-05-23 アイダエンジニアリング株式会社 Method of bonding microchip and PDMS substrate to facing substrate
WO2006127692A2 (en) 2005-05-23 2006-11-30 Hess Harald F Optical microscopy with phototransformable optical labels
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
US8699032B2 (en) 2009-01-27 2014-04-15 Panasonic Corporation Surface plasmon resonance sensor, localized plasmon resonance sensor, and method for manufacturing same
US9428789B2 (en) 2011-03-21 2016-08-30 Biodesy, Inc. Classification of kinase inhibitors using nonlinear optical techniques
EP3936622A1 (en) * 2014-06-30 2022-01-12 Bluelight Therapeutics, Inc. Methods for high throughput analysis of conformation in biological entities
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
EP3455628A4 (en) 2016-05-09 2019-12-04 Biodesy, Inc. Methods and devices for detection of peripheral membrane protein interactions using nonlinear optical techniques
US20200362397A1 (en) * 2017-05-31 2020-11-19 Centrillion Technology Holdings Corporation Oligonucleotide probe array with electronic detection system
CN110487686B (en) * 2019-09-03 2022-09-02 中国工程物理研究院流体物理研究所 Air aerosol single particle multi-mode spectrum diagnosis device and diagnosis method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9508559D0 (en) * 1995-04-27 1995-06-14 Polytech Transfer Ltd Surface second harmonic and sum-frequency generation immuno and enzyme assays
US5633724A (en) * 1995-08-29 1997-05-27 Hewlett-Packard Company Evanescent scanning of biochemical array
US5821060A (en) * 1996-08-02 1998-10-13 Atom Sciences, Inc. DNA sequencing, mapping, and diagnostic processes using hybridization chips and unlabeled DNA
JPH11119270A (en) * 1997-10-17 1999-04-30 Naoya Ogata Organic nonlinear optical material and its production
US6953694B2 (en) * 2000-12-06 2005-10-11 The Trustees Of Columbia University In The City Of New York Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces

Also Published As

Publication number Publication date
WO2002044412A1 (en) 2002-06-06
EP1346064A1 (en) 2003-09-24
AU2001278937A1 (en) 2002-06-11
CA2430430A1 (en) 2002-06-06
WO2002044412A8 (en) 2003-12-11
EP1346064A4 (en) 2005-01-19

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