IL154557A0 - Methods of treatment or prevention of autoimmune diseases with cpg-containing polynucleotide - Google Patents
Methods of treatment or prevention of autoimmune diseases with cpg-containing polynucleotideInfo
- Publication number
- IL154557A0 IL154557A0 IL15455701A IL15455701A IL154557A0 IL 154557 A0 IL154557 A0 IL 154557A0 IL 15455701 A IL15455701 A IL 15455701A IL 15455701 A IL15455701 A IL 15455701A IL 154557 A0 IL154557 A0 IL 154557A0
- Authority
- IL
- Israel
- Prior art keywords
- cpg
- prevention
- treatment
- methods
- autoimmune diseases
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22785300P | 2000-08-25 | 2000-08-25 | |
PCT/IL2001/000790 WO2002016549A2 (en) | 2000-08-25 | 2001-08-23 | METHODS OF TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES WITH CpG-CONTAINING POLYNUCLEOTIDE |
Publications (1)
Publication Number | Publication Date |
---|---|
IL154557A0 true IL154557A0 (en) | 2003-09-17 |
Family
ID=22854736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15455701A IL154557A0 (en) | 2000-08-25 | 2001-08-23 | Methods of treatment or prevention of autoimmune diseases with cpg-containing polynucleotide |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040005588A1 (ja) |
EP (1) | EP1335741A4 (ja) |
JP (1) | JP2005503320A (ja) |
AU (1) | AU2001282475A1 (ja) |
CA (1) | CA2420499A1 (ja) |
IL (1) | IL154557A0 (ja) |
WO (1) | WO2002016549A2 (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
US6420346B1 (en) * | 2000-02-07 | 2002-07-16 | Rappaport Family Institute For Research In The Medical Sciences | Polynucleotides encoding MIP-1α, MCP-1, MIP-1β, Rantes and TNF-α, and methods for treating rheumatoid arthritis |
DE10041853C1 (de) * | 2000-08-25 | 2002-02-28 | Gmd Gmbh | Konfigurierbares Mikroreaktornetzwerk |
US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
AU2002361468A1 (en) * | 2001-08-14 | 2003-03-18 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human S | Method for rapid generation of mature dendritic cells |
US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
AU2002366710A1 (en) | 2001-12-20 | 2003-07-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS |
EP1575526B1 (en) | 2002-05-21 | 2012-06-06 | Irun R. Cohen | Dna vaccines encoding heat shock proteins |
CA2388049A1 (en) | 2002-05-30 | 2003-11-30 | Immunotech S.A. | Immunostimulatory oligonucleotides and uses thereof |
US8263091B2 (en) * | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
US8017113B2 (en) | 2003-03-12 | 2011-09-13 | Rappaport Family Institute For Research In The Medical Sciences | Compositions and methods for diagnosing and treating an inflammation |
ATE394676T1 (de) | 2003-03-12 | 2008-05-15 | Rappaport Family Inst For Res | Verbindungen und verfahren zur diagnose von prostatakrebs |
US20090202618A1 (en) * | 2003-11-24 | 2009-08-13 | Yeda Research & Development Co. Ltd | Dna vaccines encoding hsp60 peptide fragments for treating autoimmune diseases |
WO2005084137A2 (en) * | 2004-03-08 | 2005-09-15 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Cd25 dna vaccines for treating and preventing t-cell mediated diseases |
WO2006072946A2 (en) * | 2005-01-04 | 2006-07-13 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Hsp60, hsp60 peptides and t cell vaccines for immunomodulation |
WO2009034110A1 (en) | 2007-09-11 | 2009-03-19 | Kobenhavns Universitet | Prevention of type 1 diabetes by administration of gliadin |
ITRM20080529A1 (it) * | 2008-10-07 | 2010-04-08 | Uni Degli Studi Perugia | Uso della l-chinurenina e suoi derivati per la prevenzione ed il trattamento del diabete mellito di tipo 1. |
CN112253120B (zh) * | 2020-11-26 | 2023-06-09 | 河南理工大学 | 煤矿废弃资源流态化共采方法 |
CN114215530B (zh) * | 2021-11-29 | 2024-04-19 | 中国矿业大学 | 一种坚硬顶板定向水压致裂沿空巷道快速掘巷方法 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0468520A3 (en) * | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6239116B1 (en) * | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
CA2194761C (en) * | 1994-07-15 | 2006-12-19 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
US6180103B1 (en) * | 1994-12-21 | 2001-01-30 | Yeda Research And Development Co., Ltd. | Peptide p277 analogs, and pharmaceutical compositions comprising them for treatment or diagnosis of diabetes |
MX9704738A (es) * | 1994-12-21 | 1997-10-31 | Yenda Res And Dev Co Ltd | Analogos de peptido p277 y composiciones farmaceuticas que los contienen, metodo de diagnostico de diabetes mellitus dependiente de la insulina y uso de los mismos. |
US6110746A (en) * | 1995-06-30 | 2000-08-29 | Yeda Research And Development Co. Ltd. | Peptides derived from human heat shock protein 60 for treatment of diabetes, compositions, methods and kits |
IL114407A0 (en) * | 1995-06-30 | 1995-10-31 | Yeda Res & Dev | Novel peptides and pharmaceutical compositions comprising them |
US5993803A (en) * | 1996-08-30 | 1999-11-30 | Yeda Research And Development Co., Ltd. | Method of reducing the severity of host vs graft reaction by down-regulating hsp60 autoimmunity |
US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
CA2291483C (en) * | 1997-06-06 | 2012-09-18 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
EP1009413B1 (en) * | 1997-09-05 | 2007-02-14 | The Regents Of The University Of California | Use of immunostimulatory oligonucleotides for preventing or treating asthma |
US6541011B2 (en) * | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
CA2323733A1 (en) * | 1998-04-13 | 1999-10-21 | Michael B. Brenner | Vaccine compositions comprising cd-1 antigens and t-cell stimulating compound and methods of use thereof |
WO2000006588A1 (en) * | 1998-07-27 | 2000-02-10 | University Of Iowa Research Foundation | STEREOISOMERS OF CpG OLIGONUCLEOTIDES AND RELATED METHODS |
US7030098B2 (en) * | 1999-03-12 | 2006-04-18 | The Board Of Trustees Of The Leland Stanford Junior University | DNA vaccination for treatment of autoimmune disease |
BRPI0010612B8 (pt) * | 1999-04-19 | 2021-05-25 | Smithkline Beecham Biologicals S A | vacinas |
ATE378348T1 (de) * | 2000-01-14 | 2007-11-15 | Us Health | Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion |
US7544669B2 (en) * | 2001-11-21 | 2009-06-09 | The Board Of Trustees Of The Leland Stanford Junior University | Polynucleotide therapy |
EP1575526B1 (en) * | 2002-05-21 | 2012-06-06 | Irun R. Cohen | Dna vaccines encoding heat shock proteins |
GB0212648D0 (en) * | 2002-05-31 | 2002-07-10 | Immunoclin Lab Ltd | Treatment with cytokines |
AU2003290948A1 (en) * | 2002-11-15 | 2004-06-15 | The General Hospital Corporation | Screening methods to identify treatments for autoimmune disease |
-
2001
- 2001-08-23 IL IL15455701A patent/IL154557A0/xx unknown
- 2001-08-23 AU AU2001282475A patent/AU2001282475A1/en not_active Abandoned
- 2001-08-23 CA CA002420499A patent/CA2420499A1/en not_active Abandoned
- 2001-08-23 EP EP01961097A patent/EP1335741A4/en not_active Withdrawn
- 2001-08-23 JP JP2002521625A patent/JP2005503320A/ja active Pending
- 2001-08-23 WO PCT/IL2001/000790 patent/WO2002016549A2/en not_active Application Discontinuation
-
2003
- 2003-02-24 US US10/371,116 patent/US20040005588A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2420499A1 (en) | 2002-02-28 |
AU2001282475A1 (en) | 2002-03-04 |
WO2002016549A2 (en) | 2002-02-28 |
JP2005503320A (ja) | 2005-02-03 |
EP1335741A4 (en) | 2005-10-26 |
WO2002016549A3 (en) | 2002-07-18 |
US20040005588A1 (en) | 2004-01-08 |
EP1335741A2 (en) | 2003-08-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL154557A0 (en) | Methods of treatment or prevention of autoimmune diseases with cpg-containing polynucleotide | |
AU2002353783A8 (en) | Suppressors of cpg oligonucleotides and methods of use | |
IL145778A0 (en) | Methods and compositions for inhibiting the function of polynucleotide sequences | |
GB0007193D0 (en) | Treatment of movrmrnt disorders | |
IL144981A0 (en) | Treatment of autoimmune disease | |
AU8136801A (en) | Methods of preventing or treating diseases and conditions using complex carbohydrates | |
GB9927757D0 (en) | Treatment of autoimmune diseases | |
GB2360453B (en) | Treatment of skin conditions | |
HU0003409D0 (en) | Treatment or prevention of coccidiosis | |
AU2003302271A8 (en) | Methods of treating and/or preventing autoimmune diseases | |
GB2381455B (en) | Treatment of burns | |
GB0114231D0 (en) | Treatment of multiple sclerosis | |
EP1303281A4 (en) | METHODS OF TREATMENT | |
AU2001233521A1 (en) | Method of designing and selecting polynucleotide sequences | |
HUP0302882A3 (en) | Improved specificity in treatment of diseases | |
GB0105059D0 (en) | Activated sludge treatment | |
GB0010496D0 (en) | Treatment of conditions of the central nervous system | |
ZA200103250B (en) | The treatment of immunomodulatory related and other diseases or conditions. | |
GB0025655D0 (en) | Sludge treatment | |
GB0014904D0 (en) | Methods of treatment | |
GB0013928D0 (en) | Methods of treatment | |
GB0030865D0 (en) | Treatment and prevention of disease | |
GB0030866D0 (en) | Treatment and prevention of disease | |
GB0016197D0 (en) | Treatment and prevention of disease | |
AU3911901A (en) | Novel polypeptide--- a human yiplp28 and polynucleotide encoding it |