IL152018A0 - Dna encoding mammalian sphingosine kinase type 2 isoforms, proteins encoded by said dna and pharmaceutical compositions containing the same - Google Patents
Dna encoding mammalian sphingosine kinase type 2 isoforms, proteins encoded by said dna and pharmaceutical compositions containing the sameInfo
- Publication number
- IL152018A0 IL152018A0 IL15201801A IL15201801A IL152018A0 IL 152018 A0 IL152018 A0 IL 152018A0 IL 15201801 A IL15201801 A IL 15201801A IL 15201801 A IL15201801 A IL 15201801A IL 152018 A0 IL152018 A0 IL 152018A0
- Authority
- IL
- Israel
- Prior art keywords
- dna
- isoforms
- sphingosine kinase
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 102000001708 Protein Isoforms Human genes 0.000 title abstract 2
- 108010029485 Protein Isoforms Proteins 0.000 title abstract 2
- 108010035597 sphingosine kinase Proteins 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 6
- 230000030833 cell death Effects 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19431800P | 2000-04-03 | 2000-04-03 | |
| PCT/US2001/009664 WO2001074837A1 (en) | 2000-04-03 | 2001-03-26 | Mammalian sphingosine kinase type 2 isoforms, cloning, expression and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL152018A0 true IL152018A0 (en) | 2003-04-10 |
Family
ID=22717111
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15201801A IL152018A0 (en) | 2000-04-03 | 2001-03-26 | Dna encoding mammalian sphingosine kinase type 2 isoforms, proteins encoded by said dna and pharmaceutical compositions containing the same |
| IL152018A IL152018A (en) | 2000-04-03 | 2002-09-30 | DNA encoding isoforms of sphingosine kinase form 2 mammals, proteins encoded by DNA and pharmaceutical preparations containing them |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL152018A IL152018A (en) | 2000-04-03 | 2002-09-30 | DNA encoding isoforms of sphingosine kinase form 2 mammals, proteins encoded by DNA and pharmaceutical preparations containing them |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP2110379A3 (de) |
| CN (1) | CN1443192A (de) |
| AT (1) | ATE449783T1 (de) |
| AU (1) | AU2001251002B2 (de) |
| BR (1) | BR0109827A (de) |
| CZ (1) | CZ20023282A3 (de) |
| DE (1) | DE60140605D1 (de) |
| IL (2) | IL152018A0 (de) |
| NO (1) | NO20024727L (de) |
| PL (1) | PL365523A1 (de) |
| RU (1) | RU2002126264A (de) |
| ZA (1) | ZA200207930B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106975071B (zh) * | 2017-02-17 | 2019-10-29 | 苏州大学 | 一种治疗缺血性脑中风的Tat-SPK2肽及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2329124A1 (en) * | 1998-05-26 | 1999-12-02 | Office Of The Dean Of Research And Graduate Education | Sphingosine kinase, cloning, expression and methods of use |
| WO2000052173A2 (en) * | 1999-03-02 | 2000-09-08 | Nps Allelix Corp. | Cloned human sphingosine kinase homologues |
-
2001
- 2001-03-26 DE DE60140605T patent/DE60140605D1/de not_active Expired - Lifetime
- 2001-03-26 CZ CZ20023282A patent/CZ20023282A3/cs unknown
- 2001-03-26 PL PL01365523A patent/PL365523A1/xx not_active Application Discontinuation
- 2001-03-26 EP EP09010276A patent/EP2110379A3/de not_active Withdrawn
- 2001-03-26 AU AU2001251002A patent/AU2001251002B2/en not_active Ceased
- 2001-03-26 IL IL15201801A patent/IL152018A0/xx unknown
- 2001-03-26 EP EP01924340A patent/EP1268509B1/de not_active Expired - Lifetime
- 2001-03-26 AT AT01924340T patent/ATE449783T1/de not_active IP Right Cessation
- 2001-03-26 RU RU2002126264/15A patent/RU2002126264A/ru unknown
- 2001-03-26 BR BR0109827-6A patent/BR0109827A/pt not_active IP Right Cessation
- 2001-03-26 CN CN01810585A patent/CN1443192A/zh active Pending
-
2002
- 2002-09-30 IL IL152018A patent/IL152018A/en not_active IP Right Cessation
- 2002-10-02 NO NO20024727A patent/NO20024727L/no not_active Application Discontinuation
- 2002-10-02 ZA ZA200207930A patent/ZA200207930B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2110379A3 (de) | 2010-07-28 |
| DE60140605D1 (de) | 2010-01-07 |
| EP2110379A2 (de) | 2009-10-21 |
| NO20024727D0 (no) | 2002-10-02 |
| BR0109827A (pt) | 2004-07-06 |
| AU2001251002B2 (en) | 2005-10-20 |
| CN1443192A (zh) | 2003-09-17 |
| NO20024727L (no) | 2002-12-03 |
| RU2002126264A (ru) | 2004-03-20 |
| EP1268509B1 (de) | 2009-11-25 |
| EP1268509A4 (de) | 2004-09-22 |
| ZA200207930B (en) | 2004-01-27 |
| IL152018A (en) | 2008-12-29 |
| ATE449783T1 (de) | 2009-12-15 |
| PL365523A1 (en) | 2005-01-10 |
| EP1268509A1 (de) | 2003-01-02 |
| CZ20023282A3 (cs) | 2003-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0957903A4 (de) | Pharmazeutische zubereitungen und verfahren | |
| CA2189250A1 (en) | Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels | |
| BG104599A (en) | Inhibition of raf kinase using symmetrical and unsymmetrical substituted diphenyl ureas | |
| IL152659A (en) | Liquid pharmaceutical compositions comprising a pegylated human erythropoietin protein and a multiple charged inorganic anion, in a pharmaceutically acceptable buffer | |
| UA66417C2 (en) | Recombinant adenovirus affecting canines, pharmaceutical composition | |
| MY101887A (en) | A novel human physiologically active polypeptide. | |
| ATE393831T1 (de) | Zusammensetzung zur in vivo erzeugung von therapeutischen produkten | |
| MY132496A (en) | Inhibitors of p38 | |
| MY117696A (en) | INHIBITORS OF p38 | |
| EP1310558A3 (de) | Stabiele bakterizide Proteine, welche die Permeabilität erhöhen und pharmazeutische Zusammensetzungen, diese enthaltend | |
| BR9811956B1 (pt) | naftiridinonas e composição farmacêutica compreendendo as mesmas. | |
| DK0679092T3 (da) | Cytokindæmpende midler | |
| CA2026915A1 (en) | Stem cell factor | |
| IL114904A0 (en) | Adenovirus comprising a gene encoding glutathione peroxidase | |
| GB9806632D0 (en) | Peptide factor | |
| WO1997026322A3 (en) | Methods and compositions for inhibiting hexokinase | |
| LTIP610A (en) | Inhibitors of cells proliferation, pharmaceutical composition and method for preparation of compounds | |
| FR2724320B1 (fr) | Nouvel implant pour le traitement des maladies acquises | |
| IL152018A0 (en) | Dna encoding mammalian sphingosine kinase type 2 isoforms, proteins encoded by said dna and pharmaceutical compositions containing the same | |
| MX9800049A (es) | Antraquinonas mono- y disulfo-substituidas y su uso para el tratamiento de trastornos de la matriz del hueso. | |
| WO2001083722A3 (en) | Enzymes useful for treating and methods for treating mps-vi and cells lines for producing such enzymes recombinantly | |
| NZ228208A (en) | Eglin compounds (hurudin) and protease inhibitor pharmaceutical compositions | |
| DE60034874D1 (de) | Interne ribosom eintrittstelle (ires), vektor der diesen enthaltet und dessen therapeutische verwendung | |
| MY103584A (en) | 8(alpha)-acylaminoergoline, its preparation and pharmaceutical compositions containing it | |
| MY129421A (en) | INHIBITORS OF p38 |