IL148736A0 - Dexanabinol and dexanabinol analogs which regulate inflammation related genes - Google Patents
Dexanabinol and dexanabinol analogs which regulate inflammation related genesInfo
- Publication number
- IL148736A0 IL148736A0 IL14873602A IL14873602A IL148736A0 IL 148736 A0 IL148736 A0 IL 148736A0 IL 14873602 A IL14873602 A IL 14873602A IL 14873602 A IL14873602 A IL 14873602A IL 148736 A0 IL148736 A0 IL 148736A0
- Authority
- IL
- Israel
- Prior art keywords
- dexanabinol
- analogs
- related genes
- inflammation related
- regulate inflammation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P11/06—Antiasthmatics
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14873602A IL148736A0 (en) | 2002-03-18 | 2002-03-18 | Dexanabinol and dexanabinol analogs which regulate inflammation related genes |
PCT/IL2003/000223 WO2003077832A2 (en) | 2002-03-18 | 2003-03-16 | Dexanabinol and dexanabinol analogs regulate inflammation related genes |
CA002479676A CA2479676A1 (en) | 2002-03-18 | 2003-03-16 | Dexanabinol and dexanabinol analogs regulate inflammation related genes |
EP03710188A EP1485083A4 (en) | 2002-03-18 | 2003-03-16 | DEXANABINOL AND DEXANABINOL ANALOGUES REGULATING GENES ASSOCIATED WITH INFLAMMATION |
IL16387703A IL163877A0 (en) | 2002-03-18 | 2003-03-16 | Dexanabinol and dexanabinol analogsregulate inflammation related genes |
AU2003214608A AU2003214608A1 (en) | 2002-03-18 | 2003-03-16 | Dexanabinol and dexanabinol analogs regulate inflammation related genes |
JP2003575886A JP2005526768A (ja) | 2002-03-18 | 2003-03-16 | 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 |
ZA200407182A ZA200407182B (en) | 2002-03-18 | 2004-09-08 | Dexanabinol and dexanabinol analogs regulate inflammation releated genes. |
US10/942,504 US20050137251A1 (en) | 2002-03-18 | 2004-09-16 | Dexanabinol and dexanabinol analogs regulate inflammation related genes |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14873602A IL148736A0 (en) | 2002-03-18 | 2002-03-18 | Dexanabinol and dexanabinol analogs which regulate inflammation related genes |
Publications (1)
Publication Number | Publication Date |
---|---|
IL148736A0 true IL148736A0 (en) | 2002-09-12 |
Family
ID=27840273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14873602A IL148736A0 (en) | 2002-03-18 | 2002-03-18 | Dexanabinol and dexanabinol analogs which regulate inflammation related genes |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1485083A4 (ja) |
JP (1) | JP2005526768A (ja) |
AU (1) | AU2003214608A1 (ja) |
CA (1) | CA2479676A1 (ja) |
IL (1) | IL148736A0 (ja) |
WO (1) | WO2003077832A2 (ja) |
ZA (1) | ZA200407182B (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0326393D0 (en) * | 2003-11-12 | 2003-12-17 | Ares Trading Sa | Cytokine antagonist molecules |
US20110177538A1 (en) * | 2004-07-23 | 2011-07-21 | Sara Mangialaio | Biomarkers for rheumatoid arthritis (ra) |
WO2006024958A2 (en) * | 2004-08-09 | 2006-03-09 | Novimmune S.A. | Cannabinoid compositions and methods of use thereof |
BRPI0520129A2 (pt) * | 2005-03-17 | 2009-04-28 | Proyecto Biomedicina Cima Sl | uso de 5'-metiltioadenosina (mta) na prevenÇço e/ou no tratamento de doenÇas auto-imunes e/ou rejeiÇço de transplante |
EP1752149A1 (en) * | 2005-07-29 | 2007-02-14 | Laboratorios Del Dr. Esteve, S.A. | CB1 Antagonists or inverse agonists as therapeutical agents for the treatment of inflammation involving gene expression |
DK1903866T3 (en) * | 2005-11-07 | 2016-07-25 | Murty Pharmaceuticals Inc | Improved release of tetrahydrocannabinol |
CN101240271B (zh) * | 2006-08-28 | 2012-08-29 | 长春华普生物技术有限公司 | Toll样受体调节性寡核苷酸及其用途 |
GB0713116D0 (en) * | 2007-07-06 | 2007-08-15 | Therapeutics Ltd E | Treatment of melanoma |
GB0719771D0 (en) * | 2007-10-10 | 2007-11-21 | Therapeutics Ltd E | Dexanabinol in combination with inhibitors of BRAF or MEK for the treatment of melanoma |
GB0915877D0 (en) | 2009-09-10 | 2009-10-14 | E Therapeutics Plc | Cancer cell apoptosis |
GB201207305D0 (en) * | 2012-04-26 | 2012-06-13 | E Therapeutics Plc | Therapy |
JP6226278B2 (ja) * | 2012-08-03 | 2017-11-08 | 国立大学法人愛媛大学 | 免疫細胞の活性化抑制剤およびその用途 |
WO2017068349A1 (en) | 2015-10-23 | 2017-04-27 | E-Therapeutics Plc | Cannabinoid for use in immunotherapy |
JP6470879B1 (ja) * | 2017-03-08 | 2019-02-13 | 日清オイリオグループ株式会社 | 抗炎症剤、抗炎症用医薬組成物、抗炎症用食品組成物 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115245A (en) * | 1995-09-11 | 2002-12-01 | Yissum Res Dev Co | Tumor necrosis factor inhibiting pharmaceuticals |
EP1299374B1 (en) * | 2000-06-22 | 2006-12-27 | Pharmos Corporation | Novel non-psychotropic cannabinoids |
-
2002
- 2002-03-18 IL IL14873602A patent/IL148736A0/xx unknown
-
2003
- 2003-03-16 WO PCT/IL2003/000223 patent/WO2003077832A2/en active Application Filing
- 2003-03-16 AU AU2003214608A patent/AU2003214608A1/en not_active Abandoned
- 2003-03-16 CA CA002479676A patent/CA2479676A1/en not_active Abandoned
- 2003-03-16 EP EP03710188A patent/EP1485083A4/en not_active Withdrawn
- 2003-03-16 JP JP2003575886A patent/JP2005526768A/ja not_active Abandoned
-
2004
- 2004-09-08 ZA ZA200407182A patent/ZA200407182B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2003077832A3 (en) | 2003-12-31 |
WO2003077832A2 (en) | 2003-09-25 |
JP2005526768A (ja) | 2005-09-08 |
CA2479676A1 (en) | 2003-09-25 |
ZA200407182B (en) | 2006-02-22 |
EP1485083A4 (en) | 2008-11-19 |
AU2003214608A1 (en) | 2003-09-29 |
EP1485083A2 (en) | 2004-12-15 |
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