IL148342A0 - Methylenen blue diagnostic agent and diagnostic methods for detection of epithelial cancer - Google Patents

Methylenen blue diagnostic agent and diagnostic methods for detection of epithelial cancer

Info

Publication number
IL148342A0
IL148342A0 IL14834200A IL14834200A IL148342A0 IL 148342 A0 IL148342 A0 IL 148342A0 IL 14834200 A IL14834200 A IL 14834200A IL 14834200 A IL14834200 A IL 14834200A IL 148342 A0 IL148342 A0 IL 148342A0
Authority
IL
Israel
Prior art keywords
methylenen
diagnostic
detection
blue
epithelial cancer
Prior art date
Application number
IL14834200A
Original Assignee
Zila Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zila Inc filed Critical Zila Inc
Publication of IL148342A0 publication Critical patent/IL148342A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL14834200A 2000-06-30 2000-06-30 Methylenen blue diagnostic agent and diagnostic methods for detection of epithelial cancer IL148342A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/018161 WO2002003048A1 (en) 2000-06-30 2000-06-30 Methylene blue diagnostic agent and diagnostic methods for detection of epithelial cancer

Publications (1)

Publication Number Publication Date
IL148342A0 true IL148342A0 (en) 2002-09-12

Family

ID=21741552

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14834200A IL148342A0 (en) 2000-06-30 2000-06-30 Methylenen blue diagnostic agent and diagnostic methods for detection of epithelial cancer

Country Status (9)

Country Link
EP (1) EP1212600A4 (en)
JP (1) JP2004502704A (en)
CN (1) CN1372637A (en)
AU (1) AU781042B2 (en)
CA (1) CA2383194A1 (en)
IL (1) IL148342A0 (en)
MX (1) MXPA02002183A (en)
NO (1) NO20020959L (en)
WO (1) WO2002003048A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004295148A1 (en) * 2003-11-28 2005-06-16 Photopharmica Limited Developments in biologically active methylene blue derivatives (2)
AU2004324049A1 (en) * 2004-09-30 2006-04-20 Zila Biotechnology, Inc. Light-directed method for detecting and aiding further evaluation of abnormal mucosal tissue
WO2007083703A1 (en) * 2006-01-18 2007-07-26 Arkray, Inc. Liquid reagent of color former and method of stabilizing the same
ITUD20080073A1 (en) * 2008-04-04 2009-10-05 Giuseppe Augusto Scigliano PHARMACEUTICAL COMPOSITION AND ITS DIAGNOSTIC AND THERAPEUTIC USE
US9518963B2 (en) 2011-08-26 2016-12-13 Waters Technologies Corporation Electrospray emitter assemblies for microfluidic chromatography apparatus
CN105510321A (en) * 2011-12-29 2016-04-20 闫文广 Detection agent composition for epithelial tissue tumor cells and preparing method thereof
PT106082A (en) * 2012-01-04 2013-07-04 Fernando Jorge Neves Ferreira FIXING COMPOSITION FOR CYTOLOGY, CELL FITTING METHOD AND ITS APPLICATIONS
CN104483473B (en) * 2014-12-31 2016-03-02 广州市微米生物科技有限公司 For detection reagent and the preparation and determination methods method of epithelial neoplasms cell
US11413240B2 (en) 2016-12-29 2022-08-16 Board Of Regents, The University Of Texas System Methylene blue solution for the treatment of oral lesions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321251A (en) * 1979-12-19 1982-03-23 The United States Of America As Represented By The Department Of Health And Human Services Detection of malignant lesions of the oral cavity utilizing toluidine blue rinse
US5485527A (en) * 1985-11-04 1996-01-16 Becton Dickinson And Company Apparatus and method for analyses of biological specimens
JPH028720A (en) * 1988-06-27 1990-01-12 Toagosei Chem Ind Co Ltd Temperature detection body
KR100242727B1 (en) * 1991-10-31 2000-03-02 에드윈 포머란츠 Biological stain composition, method of preparation and method of use for delineation of epithelial cancer
US5301688A (en) * 1992-08-07 1994-04-12 Physion S.R.L. Method for localization and therapy of occult bladder cancer
EP0814847B1 (en) * 1996-01-16 2003-11-05 Zila, Inc. Methods and compositions for in-vivo detection of oral cancers and precancerous conditions
AU8414098A (en) * 1997-08-19 1999-03-08 Emory University Noscapine derivatives, useful as anticancer agents

Also Published As

Publication number Publication date
CA2383194A1 (en) 2002-01-10
WO2002003048A8 (en) 2002-07-25
EP1212600A4 (en) 2007-10-10
CN1372637A (en) 2002-10-02
EP1212600A1 (en) 2002-06-12
WO2002003048A1 (en) 2002-01-10
AU781042B2 (en) 2005-05-05
MXPA02002183A (en) 2002-09-30
NO20020959L (en) 2002-04-24
JP2004502704A (en) 2004-01-29
NO20020959D0 (en) 2002-02-27
AU3554902A (en) 2002-04-22

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