IL144082A0 - Crystal structure of antibiotics bound to the 30s ribosome and its use - Google Patents

Crystal structure of antibiotics bound to the 30s ribosome and its use

Info

Publication number
IL144082A0
IL144082A0 IL14408201A IL14408201A IL144082A0 IL 144082 A0 IL144082 A0 IL 144082A0 IL 14408201 A IL14408201 A IL 14408201A IL 14408201 A IL14408201 A IL 14408201A IL 144082 A0 IL144082 A0 IL 144082A0
Authority
IL
Israel
Prior art keywords
ribosome
crystal structure
antibiotics bound
antibiotics
bound
Prior art date
Application number
IL14408201A
Other languages
English (en)
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0017376A external-priority patent/GB0017376D0/en
Priority claimed from GB0029872A external-priority patent/GB0029872D0/en
Priority claimed from GBGB0029870.3A external-priority patent/GB0029870D0/en
Priority claimed from GB0110885A external-priority patent/GB0110885D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Publication of IL144082A0 publication Critical patent/IL144082A0/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30—Drug targeting using structural data; Docking or binding prediction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Theoretical Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL14408201A 2000-07-14 2001-07-01 Crystal structure of antibiotics bound to the 30s ribosome and its use IL144082A0 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0017376A GB0017376D0 (en) 2000-07-14 2000-07-14 Crystal structure
GB0022943A GB0022943D0 (en) 2000-07-14 2000-09-19 Crystal structure (II)
GB0029872A GB0029872D0 (en) 2000-07-14 2000-12-07 Crystal structure (III)
GBGB0029870.3A GB0029870D0 (en) 2000-07-14 2000-12-07 Crystal structure (IV)
GBGB0029871.1A GB0029871D0 (en) 2000-07-14 2000-12-07 Crystal structure (V)
GB0110885A GB0110885D0 (en) 2000-07-14 2001-05-03 Crystal structure (VI)

Publications (1)

Publication Number Publication Date
IL144082A0 true IL144082A0 (en) 2002-05-23

Family

ID=27546602

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14408201A IL144082A0 (en) 2000-07-14 2001-07-01 Crystal structure of antibiotics bound to the 30s ribosome and its use

Country Status (7)

Country Link
US (1) US20020072861A1 (ja)
EP (1) EP1186614A3 (ja)
JP (1) JP2003212895A (ja)
AU (1) AU783166B2 (ja)
CA (1) CA2352036A1 (ja)
GB (1) GB2368067B (ja)
IL (1) IL144082A0 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6947844B2 (en) 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
US6638908B1 (en) 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
EP1351982B1 (en) 2000-12-09 2008-02-13 The Regents Of The University Of California X ray crystal structures at 5.5 a resolution of functional complexes of the bacterial ribosome containing transfer rna and model messenger rnas
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
EP1308457B1 (en) * 2001-08-03 2013-12-04 Yale University Ribosome structure and protein synthesis inhibitors
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
US20070118296A1 (en) * 2003-11-07 2007-05-24 Dna Software Inc. System and methods for three dimensional molecular structural analysis
KR20150016336A (ko) * 2012-05-21 2015-02-11 더 스크립스 리서치 인스티튜트 리보솜 폴리뉴클레오티드 및 관련 발현 시스템
WO2016120868A1 (en) 2015-01-29 2016-08-04 Yeda Research And Development Co. Ltd. Crystal structure of the large ribosomal subunit from s. aureus
EP3076181A1 (en) * 2015-03-31 2016-10-05 Centre National De La Recherche Scientifique (Cnrs) Atomic structure of the human 80s ribosome
JP7261346B1 (ja) 2022-12-20 2023-04-19 賢三 小俣 アミデーション反応のシミュレーション方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US6183121B1 (en) * 1997-08-14 2001-02-06 Vertex Pharmaceuticals Inc. Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets
AU759378B2 (en) * 1998-02-06 2003-04-10 Ilexus Pty Limited Three-dimensional structures and models of Fc receptors and uses thereof

Also Published As

Publication number Publication date
GB2368067B (en) 2004-11-10
GB0117142D0 (en) 2001-09-05
JP2003212895A (ja) 2003-07-30
US20020072861A1 (en) 2002-06-13
EP1186614A2 (en) 2002-03-13
GB2368067A (en) 2002-04-24
CA2352036A1 (en) 2002-01-14
EP1186614A3 (en) 2002-03-20
AU7215801A (en) 2002-01-24
AU783166B2 (en) 2005-09-29

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