IL141943A0 - Modulation of endothelial cell surface receptor activity - Google Patents

Modulation of endothelial cell surface receptor activity

Info

Publication number
IL141943A0
IL141943A0 IL14194399A IL14194399A IL141943A0 IL 141943 A0 IL141943 A0 IL 141943A0 IL 14194399 A IL14194399 A IL 14194399A IL 14194399 A IL14194399 A IL 14194399A IL 141943 A0 IL141943 A0 IL 141943A0
Authority
IL
Israel
Prior art keywords
modulation
cell surface
endothelial cell
receptor activity
surface receptor
Prior art date
Application number
IL14194399A
Other languages
English (en)
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Publication of IL141943A0 publication Critical patent/IL141943A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
IL14194399A 1998-09-11 1999-08-31 Modulation of endothelial cell surface receptor activity IL141943A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/152,160 US6248327B1 (en) 1998-09-11 1998-09-11 Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
PCT/US1999/019965 WO2000015258A1 (en) 1998-09-11 1999-08-31 Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis

Publications (1)

Publication Number Publication Date
IL141943A0 true IL141943A0 (en) 2002-03-10

Family

ID=22541740

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14194399A IL141943A0 (en) 1998-09-11 1999-08-31 Modulation of endothelial cell surface receptor activity

Country Status (8)

Country Link
US (1) US6248327B1 (pt)
EP (1) EP1109578A4 (pt)
JP (1) JP2002524099A (pt)
AU (1) AU752649B2 (pt)
CA (1) CA2343220A1 (pt)
IL (1) IL141943A0 (pt)
NZ (1) NZ510450A (pt)
WO (1) WO2000015258A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176289B1 (en) 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
CA2401621A1 (en) * 2000-03-01 2001-09-07 Vanderbilt University Modulation of the activity of the endothelial cel surface receptor ecrtp/dep-1 in the regulation of angiogenesis
AUPR598901A0 (en) * 2001-06-28 2001-07-19 Unisearch Limited Inhibition of angiogenesis by targeting protein tyrosine phosphatases
AU2003219796A1 (en) 2002-02-20 2003-09-09 Beth Israel Deaconess Medical Center Conjugates comprising a biodegradable polymer and uses therefor
JP2005528362A (ja) * 2002-03-21 2005-09-22 ユニヴァーシティ オヴ フロリダ 血管新生の調節法
WO2003079999A2 (en) * 2002-03-21 2003-10-02 California Institute Of Technology Modulation of angiogenesis through targeting of arginyl transferase (ate1)
US20030194708A1 (en) * 2002-04-10 2003-10-16 Minke Binnerts Human homolog of crossveinless materials and methods
CA2503736A1 (en) * 2002-11-26 2004-06-10 Cold Spring Harbor Laboratory Dep-1 receptor protein tyrosine phosphatase interacting proteins and related methods
KR20070007884A (ko) * 2004-04-23 2007-01-16 암젠 인크 Ｃｄ148의 혈관신생 억제 도메인의 항체
US20050287140A1 (en) * 2004-04-23 2005-12-29 Amgen Inc. Antibodies to angiogenesis inhibiting domains of CD148
US9216212B2 (en) * 2005-08-05 2015-12-22 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
US7951384B2 (en) * 2005-08-05 2011-05-31 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
JP2009532680A (ja) * 2006-03-31 2009-09-10 フェラーニ−カイル，カリマ 生物活性多タンパク質複合体を得て、かつ使用するための方法および組成物
WO2010039224A2 (en) 2008-09-30 2010-04-08 University Of Massachusetts Medical School Respiratory syncytial virus (rsv) sequences for protein expression and vaccines
US20120183546A1 (en) 2009-09-23 2012-07-19 Amgen Inc. Treatment of ovarian cancer using a specific binding agent of human angiopoietin-2 in combination with a taxane
WO2013003606A1 (en) 2011-06-29 2013-01-03 Amgen Inc. Predictive biomarker of survival in the treatment of renal cell carcinoma
US20190004048A1 (en) 2015-06-26 2019-01-03 Amgen Inc. Biomarker of Survival in the Treatment of Renal Cell Carcinoma with a VEGFR Inhibitor and an Ang2 Inhibitor

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595911A (en) 1990-03-14 1997-01-21 Cold Spring Harbor Laboratory Isolation of a cDNA encoding a protein tyrosine phosphatase which localizes to focal adhesions
ATE170561T1 (de) 1990-03-14 1998-09-15 Washington Res Found Methode und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen
US5660827A (en) 1992-03-05 1997-08-26 Board Of Regents, The University Of Texas System Antibodies that bind to endoglin
US5474765A (en) 1992-03-23 1995-12-12 Ut Sw Medical Ctr At Dallas Preparation and use of steroid-polyanionic polymer-based conjugates targeted to vascular endothelial cells
US5753230A (en) 1994-03-18 1998-05-19 The Scripps Research Institute Methods and compositions useful for inhibition of angiogenesis
US5639725A (en) 1994-04-26 1997-06-17 Children's Hospital Medical Center Corp. Angiostatin protein
ATE236983T1 (de) 1994-05-03 2003-04-15 Cold Spring Harbor Lab Durch zelldichte stimulierte protein-tyrosin- phosphatasen
US5912138A (en) 1996-07-25 1999-06-15 Cold Spring Harbor Laboratory Substrate trapping protein tyrosine phosphatases
WO1999002704A2 (en) 1997-07-08 1999-01-21 Cold Spring Harbor Laboratory Dual specifically phosphatase and methods of use

Also Published As

Publication number Publication date
EP1109578A4 (en) 2004-03-31
JP2002524099A (ja) 2002-08-06
NZ510450A (en) 2003-12-19
WO2000015258A1 (en) 2000-03-23
AU752649B2 (en) 2002-09-26
AU5797799A (en) 2000-04-03
CA2343220A1 (en) 2000-03-23
US6248327B1 (en) 2001-06-19
EP1109578A1 (en) 2001-06-27

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