IL140324A0 - Inhibition of transcription factor nf-kb - Google Patents
Inhibition of transcription factor nf-kbInfo
- Publication number
- IL140324A0 IL140324A0 IL14032499A IL14032499A IL140324A0 IL 140324 A0 IL140324 A0 IL 140324A0 IL 14032499 A IL14032499 A IL 14032499A IL 14032499 A IL14032499 A IL 14032499A IL 140324 A0 IL140324 A0 IL 140324A0
- Authority
- IL
- Israel
- Prior art keywords
- inhibition
- transcription factor
- transcription
- factor
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9001698P | 1998-06-19 | 1998-06-19 | |
PCT/US1999/013897 WO1999065495A1 (en) | 1998-06-19 | 1999-06-18 | INHIBITORS OF TRANSCRIPTION FACTOR NF-λB |
Publications (1)
Publication Number | Publication Date |
---|---|
IL140324A0 true IL140324A0 (en) | 2002-02-10 |
Family
ID=22220761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14032499A IL140324A0 (en) | 1998-06-19 | 1999-06-18 | Inhibition of transcription factor nf-kb |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1085872A4 (en) |
JP (1) | JP2002518333A (en) |
KR (1) | KR20010052990A (en) |
CN (1) | CN1306428A (en) |
AR (1) | AR019871A1 (en) |
AU (1) | AU4699699A (en) |
BR (1) | BR9911151A (en) |
CA (1) | CA2335293A1 (en) |
CO (1) | CO5080752A1 (en) |
CZ (1) | CZ20004760A3 (en) |
HU (1) | HUP0102492A2 (en) |
IL (1) | IL140324A0 (en) |
NO (1) | NO20006452L (en) |
PL (1) | PL345577A1 (en) |
TR (1) | TR200003779T2 (en) |
WO (1) | WO1999065495A1 (en) |
ZA (1) | ZA200007448B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4138013B2 (en) | 1996-12-23 | 2008-08-20 | イミュネックス・コーポレーション | Ligand for receptor activator of NF-KAPPA B, a member of TNF superfamily |
US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
PT2009025E (en) | 1998-05-14 | 2011-09-19 | Immunex Corp | Method of inhibiting osteoclast activity |
JP5512909B2 (en) * | 2000-01-24 | 2014-06-04 | ジェンザイム・コーポレーション | JAK / STAT pathway inhibitors and uses thereof |
US20060148732A1 (en) * | 2000-11-17 | 2006-07-06 | Gutterman Jordan U | Inhibition of NF-kappaB by triterpene compositions |
US7425580B2 (en) | 2004-05-19 | 2008-09-16 | Wyeth | (Diaryl-methyl)-malononitriles and their use as estrogen receptor ligands |
US7812018B2 (en) | 2006-02-16 | 2010-10-12 | Millennium Pharmaceuticals, Inc. | Alpha carbolines and uses thereof |
CN102171204B (en) | 2008-10-02 | 2014-08-20 | 旭化成制药株式会社 | 8-substituted isoquinoline derivative and use thereof |
US9127016B2 (en) | 2009-03-20 | 2015-09-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Small molecule inhibitors of Dusp6 and uses therefor |
EP2461806A4 (en) | 2009-07-31 | 2012-12-26 | Us Health | Antiangiogenic small molecules and methods of use |
WO2012109527A2 (en) | 2011-02-10 | 2012-08-16 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Class of hdac inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury |
US9670236B2 (en) | 2012-10-31 | 2017-06-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury |
-
1998
- 1998-06-18 HU HU0102492A patent/HUP0102492A2/en unknown
-
1999
- 1999-06-17 CO CO99037918A patent/CO5080752A1/en unknown
- 1999-06-18 AR ARP990102952A patent/AR019871A1/en unknown
- 1999-06-18 TR TR2000/03779T patent/TR200003779T2/en unknown
- 1999-06-18 JP JP2000554375A patent/JP2002518333A/en not_active Withdrawn
- 1999-06-18 PL PL99345577A patent/PL345577A1/en not_active Application Discontinuation
- 1999-06-18 BR BR9911151-9A patent/BR9911151A/en not_active Application Discontinuation
- 1999-06-18 IL IL14032499A patent/IL140324A0/en unknown
- 1999-06-18 CN CN99807572A patent/CN1306428A/en active Pending
- 1999-06-18 KR KR1020007014385A patent/KR20010052990A/en not_active Application Discontinuation
- 1999-06-18 AU AU46996/99A patent/AU4699699A/en not_active Abandoned
- 1999-06-18 CZ CZ20004760A patent/CZ20004760A3/en unknown
- 1999-06-18 CA CA002335293A patent/CA2335293A1/en not_active Abandoned
- 1999-06-18 WO PCT/US1999/013897 patent/WO1999065495A1/en not_active Application Discontinuation
- 1999-06-18 EP EP99930459A patent/EP1085872A4/en not_active Withdrawn
-
2000
- 2000-12-13 ZA ZA200007448A patent/ZA200007448B/en unknown
- 2000-12-18 NO NO20006452A patent/NO20006452L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1999065495A1 (en) | 1999-12-23 |
JP2002518333A (en) | 2002-06-25 |
CA2335293A1 (en) | 1999-12-23 |
PL345577A1 (en) | 2001-12-17 |
CO5080752A1 (en) | 2001-09-25 |
KR20010052990A (en) | 2001-06-25 |
HUP0102492A2 (en) | 2001-11-28 |
TR200003779T2 (en) | 2001-06-21 |
BR9911151A (en) | 2001-03-06 |
NO20006452D0 (en) | 2000-12-18 |
CZ20004760A3 (en) | 2001-08-15 |
EP1085872A4 (en) | 2003-04-16 |
AU4699699A (en) | 2000-01-05 |
NO20006452L (en) | 2001-02-16 |
ZA200007448B (en) | 2001-12-12 |
EP1085872A1 (en) | 2001-03-28 |
CN1306428A (en) | 2001-08-01 |
AR019871A1 (en) | 2002-03-20 |
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