IL139817A - Non-hydrated gabapentin polymorpha process for thepreparation thereof and the use thereof for the p reparation of pharmaceutical grade gabapentin - Google Patents
Non-hydrated gabapentin polymorpha process for thepreparation thereof and the use thereof for the p reparation of pharmaceutical grade gabapentinInfo
- Publication number
- IL139817A IL139817A IL13981799A IL13981799A IL139817A IL 139817 A IL139817 A IL 139817A IL 13981799 A IL13981799 A IL 13981799A IL 13981799 A IL13981799 A IL 13981799A IL 139817 A IL139817 A IL 139817A
- Authority
- IL
- Israel
- Prior art keywords
- gabapentin
- thepreparation
- polymorpha
- reparation
- hydrated
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title 4
- 229960002870 gabapentin Drugs 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009801078A ES2137137B1 (es) | 1998-05-25 | 1998-05-25 | Nuevo polimorfo de gabapentina no hidratada, su procedimiento de obtencion y su utilizacion para la obtencion de gabapentina de calidad farmaceutica. |
PCT/ES1999/000127 WO1999061408A1 (fr) | 1998-05-25 | 1999-05-10 | Polymorphe de gabapentine non hydratee, son procede d'obtention et son utilisation pour l'obtention de gabapentine a usage pharmaceutique |
Publications (2)
Publication Number | Publication Date |
---|---|
IL139817A0 IL139817A0 (en) | 2002-02-10 |
IL139817A true IL139817A (en) | 2005-11-20 |
Family
ID=8303893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13981799A IL139817A (en) | 1998-05-25 | 1999-05-10 | Non-hydrated gabapentin polymorpha process for thepreparation thereof and the use thereof for the p reparation of pharmaceutical grade gabapentin |
Country Status (9)
Country | Link |
---|---|
US (1) | US6521787B1 (fr) |
EP (1) | EP1083164B1 (fr) |
AU (1) | AU3710699A (fr) |
CA (1) | CA2333408A1 (fr) |
DE (1) | DE69912773T2 (fr) |
ES (1) | ES2137137B1 (fr) |
HU (1) | HUP0102104A3 (fr) |
IL (1) | IL139817A (fr) |
WO (1) | WO1999061408A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000061188A1 (fr) | 1999-04-09 | 2000-10-19 | Euro-Celtique S.A. | Composition de blocage du canal sodique et leur utilisation |
ES2164527B1 (es) * | 1999-04-26 | 2003-04-01 | Medichen S A | Procedimiento de obtencion de gabapentina de calidad farmaceutica. |
SI1423168T1 (sl) | 2001-09-03 | 2006-06-30 | Newron Pharm Spa | Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba |
US6800782B2 (en) | 2001-10-09 | 2004-10-05 | Warner-Lambert Co. | Anhydrous crystalline forms of gabapentin |
ITMI20022071A1 (it) * | 2002-10-01 | 2004-04-02 | Erregierre Spa | Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato. |
US7417036B2 (en) | 2002-11-12 | 2008-08-26 | Tianjin Kinsly Pharmaceutical Co. Ltd. | Crystal form of adefovir dipivoxil and its preparation |
WO2004106281A1 (fr) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Gabapentine cristallin |
US7169812B2 (en) * | 2003-07-01 | 2007-01-30 | Medtronic, Inc. | Process for producing injectable gabapentin compositions |
US20050187295A1 (en) * | 2004-02-19 | 2005-08-25 | Surendra Kalyan | Processes for the preparation of gabapentin |
US20110224435A1 (en) * | 2007-08-07 | 2011-09-15 | Ranbaxy Laboratories Limited | Process for preparation of amorphous lopinavir |
US20100222584A1 (en) * | 2009-02-06 | 2010-09-02 | Bach Pharma, Inc. | Pharmaceutical grade phthalazinediones, process for their preparation and pharmaceutical compositions containing them |
PT2858989T (pt) | 2012-05-17 | 2020-06-25 | Genentech Inc | Forma amorfa de um composto de pirimidinil-ciclopentano inibidor de akt, composições e métodos das mesmas |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
US4960931A (en) * | 1988-05-02 | 1990-10-02 | Warner-Lambert Company | Gabapentin mohohydrate and a process for producing the same |
US4894476A (en) | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
IL119890A (en) * | 1996-12-24 | 2002-03-10 | Teva Pharma | Gabapentin form iii and preparation of gabapentin form ii |
-
1998
- 1998-05-25 ES ES009801078A patent/ES2137137B1/es not_active Expired - Fee Related
-
1999
- 1999-05-10 IL IL13981799A patent/IL139817A/xx not_active IP Right Cessation
- 1999-05-10 CA CA002333408A patent/CA2333408A1/fr not_active Abandoned
- 1999-05-10 WO PCT/ES1999/000127 patent/WO1999061408A1/fr active IP Right Grant
- 1999-05-10 EP EP99919275A patent/EP1083164B1/fr not_active Expired - Lifetime
- 1999-05-10 AU AU37106/99A patent/AU3710699A/en not_active Abandoned
- 1999-05-10 HU HU0102104A patent/HUP0102104A3/hu unknown
- 1999-05-10 DE DE69912773T patent/DE69912773T2/de not_active Expired - Fee Related
- 1999-05-10 US US09/700,939 patent/US6521787B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6521787B1 (en) | 2003-02-18 |
DE69912773T2 (de) | 2004-09-30 |
ES2137137B1 (es) | 2000-08-16 |
HUP0102104A2 (hu) | 2001-11-28 |
CA2333408A1 (fr) | 1999-12-02 |
EP1083164A1 (fr) | 2001-03-14 |
EP1083164B1 (fr) | 2003-11-12 |
WO1999061408A1 (fr) | 1999-12-02 |
IL139817A0 (en) | 2002-02-10 |
HUP0102104A3 (en) | 2002-11-28 |
DE69912773D1 (de) | 2003-12-18 |
ES2137137A1 (es) | 1999-12-01 |
AU3710699A (en) | 1999-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
MM9K | Patent not in force due to non-payment of renewal fees |