IL133216A0 - 2-ä4-[4(4,5-Dichloro-2-methylimidazol-1-yl) butyl]-1 piperazinylü-5-fluoropyrimidine preparation and therapeutic use - Google Patents

2-ä4-[4(4,5-Dichloro-2-methylimidazol-1-yl) butyl]-1 piperazinylü-5-fluoropyrimidine preparation and therapeutic use

Info

Publication number
IL133216A0
IL133216A0 IL13321698A IL13321698A IL133216A0 IL 133216 A0 IL133216 A0 IL 133216A0 IL 13321698 A IL13321698 A IL 13321698A IL 13321698 A IL13321698 A IL 13321698A IL 133216 A0 IL133216 A0 IL 133216A0
Authority
IL
Israel
Prior art keywords
methylimidazol
fluoropyrimidine
dichloro
butyl
piperazinylü
Prior art date
Application number
IL13321698A
Other languages
English (en)
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of IL133216A0 publication Critical patent/IL133216A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13321698A 1997-06-02 1998-05-28 2-ä4-[4(4,5-Dichloro-2-methylimidazol-1-yl) butyl]-1 piperazinylü-5-fluoropyrimidine preparation and therapeutic use IL133216A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9706738A FR2763950B1 (fr) 1997-06-02 1997-06-02 2- {4- [4-(4,5-dichloro-2-methylimidazol-1-yl)butyl] -1- piperazinyl }-5-fluoropyrimidine, sa preparation et son utilisation therapeutique
PCT/EP1998/003190 WO1998055476A1 (fr) 1997-06-02 1998-05-28 2-{4-[4-(4,5-dichloro-2- methylimidazol-1-yl)butyl] -1-piperazinyl}-5-fluoropyrimidine, sa preparation et son utilisation therapeutique

Publications (1)

Publication Number Publication Date
IL133216A0 true IL133216A0 (en) 2001-03-19

Family

ID=9507480

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13321698A IL133216A0 (en) 1997-06-02 1998-05-28 2-ä4-[4(4,5-Dichloro-2-methylimidazol-1-yl) butyl]-1 piperazinylü-5-fluoropyrimidine preparation and therapeutic use

Country Status (22)

Country Link
US (2) US6303608B1 (hu)
EP (1) EP1007522B1 (hu)
JP (1) JP4344890B2 (hu)
KR (1) KR100556559B1 (hu)
CN (1) CN1094491C (hu)
AT (1) ATE228126T1 (hu)
AU (1) AU732722B2 (hu)
BR (1) BR9810240A (hu)
CA (1) CA2292746A1 (hu)
DE (1) DE69809564T2 (hu)
DK (1) DK1007522T3 (hu)
ES (1) ES2149691B1 (hu)
FR (1) FR2763950B1 (hu)
HU (1) HUP0002905A3 (hu)
IL (1) IL133216A0 (hu)
NO (1) NO318757B1 (hu)
NZ (1) NZ501566A (hu)
PL (1) PL190777B1 (hu)
PT (1) PT1007522E (hu)
RU (1) RU2191184C2 (hu)
TR (1) TR199903001T2 (hu)
WO (1) WO1998055476A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101152658B1 (ko) * 2009-04-30 2012-06-18 한국과학기술연구원 세로토닌 5-ｈｔ6 길항 활성 효과를 갖는 피페라진 화합물 함유 조성물
RU2660583C1 (ru) * 2017-08-15 2018-07-06 Общество С Ограниченной Ответственностью "Валента - Интеллект" Применение буспирона для лечения функционального головокружения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642759B1 (fr) * 1989-02-09 1991-05-17 Laboratorios Esteve Sa Derives de pyrimidyl-piperazinyl-alkyl azoles avec activite anxiolytique et/ou tranquillisante
FR2672052B1 (fr) 1991-01-28 1995-05-24 Esteve Labor Dr Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments.
FR2673628B1 (fr) * 1991-03-07 1993-07-09 Esteve Labor Dr Procede de preparation de derives d'aryl (ou heteroaryl)-piperazinyl-butyl-azoles.
FR2712808B1 (fr) * 1993-11-25 1996-02-16 Esteve Labor Dr Utilisation des dérivés de 1-{4-[4-aryl(ou hétéroaryl)-1-pipérazinyl]-butyl}-1-H-azole pour la préparation de médicaments destinés au traitement des troubles de la sécrétion gastrique .
FR2742052B1 (fr) * 1995-12-12 1998-04-10 Esteve Labor Dr Utilisation des derives 1-(4-(4-aryl (ou heteroaryl)-1-piper azinyl)-buty)-1h-azole pour le traitement de la depression, des troubles obsessifs compulsifs, l'apnee du sommeil, les dysfonctions sexuelles, l'emese et le mal des transports

Also Published As

Publication number Publication date
JP4344890B2 (ja) 2009-10-14
ES2149691A1 (es) 2000-11-01
HUP0002905A3 (en) 2002-01-28
FR2763950B1 (fr) 2002-09-20
DE69809564T2 (de) 2003-07-10
PL337113A1 (en) 2000-07-31
ES2149691B1 (es) 2001-05-16
WO1998055476A1 (fr) 1998-12-10
CN1261888A (zh) 2000-08-02
PT1007522E (pt) 2003-04-30
NZ501566A (en) 2001-06-29
ATE228126T1 (de) 2002-12-15
NO995894L (no) 2000-02-01
US6303608B1 (en) 2001-10-16
DE69809564D1 (de) 2003-01-02
CA2292746A1 (fr) 1998-12-10
HUP0002905A2 (hu) 2001-06-28
AU7917098A (en) 1998-12-21
RU2191184C2 (ru) 2002-10-20
PL190777B1 (pl) 2006-01-31
KR100556559B1 (ko) 2006-03-06
EP1007522B1 (fr) 2002-11-20
EP1007522A1 (fr) 2000-06-14
FR2763950A1 (fr) 1998-12-04
US6346620B1 (en) 2002-02-12
NO318757B1 (no) 2005-05-02
DK1007522T3 (da) 2003-03-17
BR9810240A (pt) 2000-09-05
JP2002501539A (ja) 2002-01-15
NO995894D0 (no) 1999-12-01
TR199903001T2 (xx) 2000-07-21
AU732722B2 (en) 2001-04-26
KR20010013274A (ko) 2001-02-26
CN1094491C (zh) 2002-11-20

Similar Documents

Publication Publication Date Title
NO324230B1 (no) Anvendelse av 1- [4-(5-cyanindol-3yl)butyl ]-4-(2-karbamoylbenzofuran-5-yl)-piperazin og dets fysiologisk akseptable salter til fremstilling av medikamenter for behandling av bipolare forstyrrelser og mani
DE60134453D1 (de) Pharmazeutische Zusammensetzungen zur Behandlung von ZNS und anderen Krankheiten
GEP20043269B (en) Purine Derivatives, Method for Their Production and Composition Containing the Same
MY128659A (en) Novel aminodicarboxylic acid derivatives having pharmaceutical properties
ATE363282T1 (de) Zusammensetzung zur unterdrückung von magensäure
DE60220055D1 (de) 4-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)harnstoff und dessen verwendung bei der behandlung von mit glycogensynthasekinase-3 (gsk3) assoziierten leiden
ES2134709A1 (es) Utilizacion de los derivados de 1-(4-(4-aril (0 heteroaril)-1-piperazinil)-butil)-1h-azol para la preparacion de un medicamento destinado al tratamiento de los transtornos obsesivo-compulsivos, de la apnea del sueño, de las disfunciones sexuales, de la emesis y del mareo en los m
MXPA01008993A (es) Tratamiento de combinacion para depresion y ansiedad.
PL337871A1 (en) Application of a specific antagonist of the 5 ht2 receptor in production of a drug useful in treating the sleep apnoea
NZ535611A (en) Pharmaceutical composition of a PDE4 or a PDE3/4 inhibitor and a histamine receptor antagonist
IL133216A0 (en) 2-ä4-[4(4,5-Dichloro-2-methylimidazol-1-yl) butyl]-1 piperazinylü-5-fluoropyrimidine preparation and therapeutic use
NZ334571A (en) Pharmaceutical composition comprising 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-acetic acid for treating diseases induced by respiratory syncytial virus
BR0009080A (pt) Método de tratamento da apnéia do sono
HK1054198A1 (en) Novel use of (R)-(-)-2-Ä5-(4-fluorophenyl)-3-pyridylmethylaminomethylÜ-chromane and its physiologically acceptable salts.
ATE294572T1 (de) Verwendung von gepirone metabolite zur erstellungs eines medicaments zur behandlung von neurologischer krankheiten
AU2002317063A (en) Itraconazole granulations: pharmaceutical formulations for oral administration and method of preparing same
HUP0401912A3 (en) Pharmaceutically acceptable salts of 20(s)-camptothecins, process for their preparation and pharmaceutical compositions containing them
NO20010984L (no) Anvendelse av R(+)-<alfa>-(2,3-dimetoksyfenyl)-1-[2-(4-fluorfenyl)etyl]-4-piperidinmetanol for behandling av sovnforstyrrelser
MXPA04001812A (es) Nueva forma de dosificacion oral de liberacion prolongada.
WO1999019324A3 (en) Antipsychotic substituted piperidine derivatives
SE0102888D0 (sv) New formulation
WO2002036554A3 (en) Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis
HUP0100661A3 (en) Salts of paroxetine, process for their preparation and medicaments containing the compounds

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees