IL132216A0 - Multiparticulate pharmaceutical form particles constituting it method and plant for making same - Google Patents

Multiparticulate pharmaceutical form particles constituting it method and plant for making same

Info

Publication number
IL132216A0
IL132216A0 IL13221698A IL13221698A IL132216A0 IL 132216 A0 IL132216 A0 IL 132216A0 IL 13221698 A IL13221698 A IL 13221698A IL 13221698 A IL13221698 A IL 13221698A IL 132216 A0 IL132216 A0 IL 132216A0
Authority
IL
Israel
Prior art keywords
pharmaceutical form
plant
making same
particles constituting
form particles
Prior art date
Application number
IL13221698A
Other versions
IL132216A (en
Original Assignee
Prographarm Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prographarm Lab filed Critical Prographarm Lab
Publication of IL132216A0 publication Critical patent/IL132216A0/en
Publication of IL132216A publication Critical patent/IL132216A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention concerns a multiparticulate pharmaceutical form, in particular multiparticulate tablet, characterised in that it consists of a plurality of particles, preferably spheroids comprising a coating based on at least a disintegrating agent and at least a binding agent and optionally at least an active substance integrated with one another by compression, said particles or spheroids wherein the active substance is distributed within a thermoplastic material having been obtained by hot extrusion without solvent of the mixture of the active substance with the thermoplastic material and the cutting up the yarn or profile coming out of the extrusion die.
IL13221698A 1997-04-07 1998-04-07 Multiparticulate pharmaceutical form, particles constituting it, and method and apparatus for making same IL132216A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9704234A FR2761605B1 (en) 1997-04-07 1997-04-07 MULTIPARTICULAR PHARMACEUTICAL FORM, ITS CONSTITUENT PARTICLES, METHOD AND PLANT FOR THEIR MANUFACTURE
PCT/FR1998/000697 WO1998044911A1 (en) 1997-04-07 1998-04-07 Multiparticulate pharmaceutical form, particles constituting it, method and plant for making same

Publications (2)

Publication Number Publication Date
IL132216A0 true IL132216A0 (en) 2001-03-19
IL132216A IL132216A (en) 2004-12-15

Family

ID=9505605

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13221698A IL132216A (en) 1997-04-07 1998-04-07 Multiparticulate pharmaceutical form, particles constituting it, and method and apparatus for making same

Country Status (18)

Country Link
EP (1) EP0973509B1 (en)
JP (1) JP4440348B2 (en)
KR (1) KR100517952B1 (en)
CN (1) CN1184960C (en)
AT (1) ATE263548T1 (en)
AU (1) AU752270B2 (en)
BR (1) BR9809386A (en)
CA (1) CA2286472C (en)
DE (1) DE69823018T2 (en)
DK (1) DK0973509T3 (en)
ES (1) ES2217552T3 (en)
FR (1) FR2761605B1 (en)
HU (1) HU225592B1 (en)
IL (1) IL132216A (en)
NZ (1) NZ500267A (en)
PT (1) PT973509E (en)
TR (1) TR199903241T2 (en)
WO (1) WO1998044911A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814366A1 (en) * 2000-09-22 2002-03-29 Rhodia Chimie Sa PROCESS FOR GRANULATING ACTIVE MATERIALS BY LOW PRESSURE EXTRUSION FOR OBTAINING DIRECTLY COMPRESSIBLE GRANULES
FR2851178B1 (en) * 2003-02-14 2005-05-06 Ethypharm Sa EXTRUDER FOR THE MANUFACTURE OF SPHEROIDAL OR SPHEROID PARTICLES.
US7820198B2 (en) * 2004-10-19 2010-10-26 Arch Chemicals, Inc. Pool chemical tablet
SA07280459B1 (en) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. Tamper Resistant Oral Pharmaceutical Dosage Forms Comprising an Opioid Analgesic
FR2999432B1 (en) 2012-12-17 2014-12-12 Ethypharm Sa ORODISPERSIBLE COMPRESSES OBTAINED BY COMPRESSION MOLDING
CN106667775B (en) * 2017-03-08 2019-11-01 安徽仁和药业有限公司 Tablet is uniformly synthesized producing device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4122217C2 (en) * 1991-07-04 1997-02-13 Merz & Co Gmbh & Co Process for the preparation of mechanically stable, well decomposing compressed products from small active substance-containing moldings
CH685285A5 (en) * 1991-12-02 1995-05-31 Debio Rech Pharma Sa Compsn. for sustained and controlled release of peptide salt
DE4413350A1 (en) * 1994-04-18 1995-10-19 Basf Ag Retard matrix pellets and process for their production

Also Published As

Publication number Publication date
IL132216A (en) 2004-12-15
FR2761605B1 (en) 2001-02-23
KR20010006090A (en) 2001-01-15
NZ500267A (en) 2001-06-29
JP4440348B2 (en) 2010-03-24
FR2761605A1 (en) 1998-10-09
KR100517952B1 (en) 2005-09-30
HU225592B1 (en) 2007-05-02
CN1184960C (en) 2005-01-19
CN1255851A (en) 2000-06-07
AU752270B2 (en) 2002-09-12
BR9809386A (en) 2000-06-13
HUP0002334A3 (en) 2001-04-28
ES2217552T3 (en) 2004-11-01
DK0973509T3 (en) 2004-08-16
WO1998044911A1 (en) 1998-10-15
HUP0002334A2 (en) 2000-12-28
CA2286472C (en) 2007-02-06
DE69823018D1 (en) 2004-05-13
TR199903241T2 (en) 2000-09-21
JP2001519801A (en) 2001-10-23
EP0973509B1 (en) 2004-04-07
DE69823018T2 (en) 2005-04-07
CA2286472A1 (en) 1998-10-15
AU7339198A (en) 1998-10-30
ATE263548T1 (en) 2004-04-15
PT973509E (en) 2004-06-30
EP0973509A1 (en) 2000-01-26

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