EP1002793A4 - Physiologically active substances tkr2449, process for producing the same, and microorganism - Google Patents

Physiologically active substances tkr2449, process for producing the same, and microorganism

Info

Publication number
EP1002793A4
EP1002793A4 EP98923171A EP98923171A EP1002793A4 EP 1002793 A4 EP1002793 A4 EP 1002793A4 EP 98923171 A EP98923171 A EP 98923171A EP 98923171 A EP98923171 A EP 98923171A EP 1002793 A4 EP1002793 A4 EP 1002793A4
Authority
EP
European Patent Office
Prior art keywords
tkr2449
microorganism
producing
same
active substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP98923171A
Other languages
German (de)
French (fr)
Other versions
EP1002793B1 (en
EP1002793A1 (en
Inventor
Kazutoh Takesako
Mitsuhiro Ueno
Naoyuki Awazu
Yoko Uno
Ikunoshin Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Bio Inc
Original Assignee
Takara Shuzo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Shuzo Co Ltd filed Critical Takara Shuzo Co Ltd
Publication of EP1002793A1 publication Critical patent/EP1002793A1/en
Publication of EP1002793A4 publication Critical patent/EP1002793A4/en
Application granted granted Critical
Publication of EP1002793B1 publication Critical patent/EP1002793B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP98923171A 1997-06-09 1998-06-09 Physiologically active substances tkr2449, process for producing the same, and microorganism Expired - Lifetime EP1002793B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP16801197 1997-06-09
JP16801197 1997-06-09
PCT/JP1998/002530 WO1998056755A1 (en) 1997-06-09 1998-06-09 Physiologically active substances tkr2449, process for producing the same, and microorganism

Publications (3)

Publication Number Publication Date
EP1002793A1 EP1002793A1 (en) 2000-05-24
EP1002793A4 true EP1002793A4 (en) 2001-01-31
EP1002793B1 EP1002793B1 (en) 2003-09-24

Family

ID=15860158

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98923171A Expired - Lifetime EP1002793B1 (en) 1997-06-09 1998-06-09 Physiologically active substances tkr2449, process for producing the same, and microorganism

Country Status (7)

Country Link
US (1) US6303350B1 (en)
EP (1) EP1002793B1 (en)
JP (1) JP4091130B2 (en)
AU (1) AU7552098A (en)
DE (1) DE69818482T2 (en)
ES (1) ES2209140T3 (en)
WO (1) WO1998056755A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1889199A (en) * 1997-12-22 1999-07-12 Takara Shuzo Co., Ltd. Antibiotic tkr2999, process for the preparation thereof and microbe
MY141506A (en) * 2003-02-12 2010-05-14 Chugai Pharmaceutical Co Ltd Virus therapeutic drug
CN100502853C (en) * 2003-02-12 2009-06-24 中外制药株式会社 Remedy for virus disease
JP5042528B2 (en) * 2003-02-12 2012-10-03 中外製薬株式会社 Antiviral drugs
TWI330173B (en) * 2003-07-09 2010-09-11 Chugai Pharmaceutical Co Ltd Compound having anti-hcv action and its producing method
JP2006077004A (en) * 2004-08-11 2006-03-23 Chugai Pharmaceut Co Ltd Compound having anti-hcv action and medicine composition containing the same
US8183005B1 (en) 2004-08-11 2012-05-22 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical agents for treating HCV infections
EP1857456A4 (en) * 2005-02-17 2011-03-09 Chugai Pharmaceutical Co Ltd Process for producing compound with anti-hcv potency and intermediate for use therein
US20110098477A1 (en) * 2005-06-28 2011-04-28 Chugai Seiyaku Kabushiki Kaisha Method Of Producing Compound Having Anti-Hcv Activity
TW201010692A (en) * 2008-06-19 2010-03-16 Public Univ Corp Nagoya City Univ Pharmaceutical composition for treatment or prevention of hbv infection
WO2010061881A1 (en) 2008-11-26 2010-06-03 中外製薬株式会社 Oligoribonucleotide or peptide nucleic acid capable of inhibiting activity of hepatitis c virus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526936A2 (en) * 1991-08-02 1993-02-10 Merck & Co. Inc. Cholesterol-lowering agents
WO1994018157A1 (en) * 1993-02-09 1994-08-18 Merck & Co., Inc. BIOLOGICALLY ACTIVE COMPOUNDS ISOLATED FROM AEROBIC FERMENTATION OF $i(TRICHODERMA VIRIDE)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000501063A (en) 1995-06-29 2000-02-02 メルク エンド カンパニー インコーポレーテッド Farnesyl-protein transferase inhibitor combinations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526936A2 (en) * 1991-08-02 1993-02-10 Merck & Co. Inc. Cholesterol-lowering agents
WO1994018157A1 (en) * 1993-02-09 1994-08-18 Merck & Co., Inc. BIOLOGICALLY ACTIVE COMPOUNDS ISOLATED FROM AEROBIC FERMENTATION OF $i(TRICHODERMA VIRIDE)

Also Published As

Publication number Publication date
EP1002793B1 (en) 2003-09-24
WO1998056755A1 (en) 1998-12-17
JP4091130B2 (en) 2008-05-28
EP1002793A1 (en) 2000-05-24
DE69818482T2 (en) 2004-07-01
ES2209140T3 (en) 2004-06-16
DE69818482D1 (en) 2003-10-30
AU7552098A (en) 1998-12-30
US6303350B1 (en) 2001-10-16

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