IL131815A0 - Methods and compositions for modulating responsiveness to corticosteroids - Google Patents
Methods and compositions for modulating responsiveness to corticosteroidsInfo
- Publication number
- IL131815A0 IL131815A0 IL13181598A IL13181598A IL131815A0 IL 131815 A0 IL131815 A0 IL 131815A0 IL 13181598 A IL13181598 A IL 13181598A IL 13181598 A IL13181598 A IL 13181598A IL 131815 A0 IL131815 A0 IL 131815A0
- Authority
- IL
- Israel
- Prior art keywords
- corticosteroids
- compositions
- methods
- modulating responsiveness
- responsiveness
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/820,692 US6054487A (en) | 1997-03-18 | 1997-03-18 | Methods and compositions for modulating responsiveness to corticosteroids |
US1634698A | 1998-01-30 | 1998-01-30 | |
PCT/US1998/004916 WO1998041232A2 (en) | 1997-03-18 | 1998-03-12 | Compositions for modulating responsiveness to corticosteroids |
Publications (1)
Publication Number | Publication Date |
---|---|
IL131815A0 true IL131815A0 (en) | 2001-03-19 |
Family
ID=26688484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13181598A IL131815A0 (en) | 1997-03-18 | 1998-03-12 | Methods and compositions for modulating responsiveness to corticosteroids |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0998300A1 (en) |
JP (1) | JP2002504091A (en) |
KR (1) | KR20000076420A (en) |
CN (1) | CN1269722A (en) |
AU (1) | AU734756B2 (en) |
BG (1) | BG103808A (en) |
BR (1) | BR9810409A (en) |
CA (1) | CA2282845A1 (en) |
DE (1) | DE998300T1 (en) |
ES (1) | ES2146192T1 (en) |
HU (1) | HUP0104439A3 (en) |
ID (1) | ID22975A (en) |
IL (1) | IL131815A0 (en) |
NO (1) | NO994506L (en) |
NZ (1) | NZ337769A (en) |
PL (1) | PL336464A1 (en) |
SI (1) | SI20110A (en) |
SK (1) | SK122199A3 (en) |
TR (1) | TR199902615T2 (en) |
WO (1) | WO1998041232A2 (en) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
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US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US6830751B1 (en) | 1994-03-14 | 2004-12-14 | Genetics Institute, Llc | Use of IL-12 antagonists in the treatment of rheumatoid arthritis |
ZA95960B (en) * | 1994-03-14 | 1995-10-10 | Genetics Inst | Use of interleukin-12 antagonists in the treatment of autoimmune diseases |
US7704944B2 (en) | 1997-08-14 | 2010-04-27 | Yeda Research And Development Company Ltd. | Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis |
US7220717B2 (en) | 1997-08-14 | 2007-05-22 | Yeda Research And Development Company Ltd. | Interleukin-18 binding proteins, their preparation and use |
IL121860A0 (en) | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
US6184210B1 (en) | 1997-10-10 | 2001-02-06 | Cytovia, Inc. | Dipeptide apoptosis inhibitors and the use thereof |
AR015966A1 (en) * | 1997-10-17 | 2001-05-30 | Smithkline Beecham Corp | USE OF A PDE4 INHIBITOR COMPOUND FOR THE PREPARATION OF A USEFUL MEDICINAL PRODUCT FOR PRURITE TREATMENT |
ATE274920T1 (en) * | 1997-10-31 | 2004-09-15 | Wyeth Corp | USE OF ANTI-IL-12 ANTIBODIES IN TRANSPLANT REJECTION |
EP1516630A3 (en) * | 1997-10-31 | 2006-05-03 | Wyeth | Use of anti-il-12 antibodies in transplantation rejection |
WO1999025737A1 (en) * | 1997-11-19 | 1999-05-27 | Tanox Pharma B.V. | Compositions and methods for treatment of autoimmune diseases, using a monoclonal antibody to the interleukin-12 beta2-chain |
AU755273B2 (en) * | 1998-03-16 | 2002-12-05 | Cytovia, Inc. | Dipeptide caspase inhibitors and the use thereof |
WO2001045747A1 (en) * | 1998-11-27 | 2001-06-28 | Technion Research & Development Foundation Ltd. | Interferon gamma inducing factor based vaccine and use of same for protective immunity against multiple sclerosis |
DE69927520T2 (en) * | 1998-12-09 | 2006-06-22 | Protein Design Labs, Inc., Fremont | USE OF IL-12 ANTIBODIES FOR THE TREATMENT OF PSORIASIS |
CA2367340A1 (en) | 1999-03-16 | 2000-09-21 | Cytovia, Inc. | Substituted 2-aminobenzamide caspase inhibitors and the use thereof |
US7883704B2 (en) | 1999-03-25 | 2011-02-08 | Abbott Gmbh & Co. Kg | Methods for inhibiting the activity of the P40 subunit of human IL-12 |
US6914128B1 (en) | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
DE19915465A1 (en) * | 1999-04-06 | 2000-10-19 | Apotech Res & Dev Ltd | Use of a caspase inhibitor to inhibit cell proliferation and use of one or more caspase inhibitors to treat diseases based on lymphocyte hyperproliferation or to suppress an immune response by lymphocytes |
CN1176941C (en) | 1999-04-09 | 2004-11-24 | 西托维亚公司 | Caspase inhibitors and the use thereof |
IL131047A0 (en) * | 1999-07-22 | 2001-01-28 | Yeda Res & Dev | Use of il-18 inhibitors |
JP2003508379A (en) | 1999-08-27 | 2003-03-04 | サイトビア インコーポレイテッド | Substituted α-hydroxy acid caspase inhibitors and uses thereof |
WO2001019373A2 (en) * | 1999-09-17 | 2001-03-22 | Basf Aktiengesellschaft | Methods and compositions for modulating responsiveness to corticosteroids |
US6566338B1 (en) | 1999-10-12 | 2003-05-20 | Cytovia, Inc. | Caspase inhibitors for the treatment and prevention of chemotherapy and radiation therapy induced cell death |
TWI373343B (en) | 2000-02-10 | 2012-10-01 | Abbott Gmbh & Co Kg | Antibodies that bind human interleukin-18 and methods of making and using |
JP2003535148A (en) * | 2000-06-06 | 2003-11-25 | グラクソ グループ リミテッド | How to treat cancer |
AU7250301A (en) * | 2000-06-22 | 2002-01-02 | Willy Ben Moussa Ben Mohammed | Use of glucocorticosteroids for producing a medicament to treat oligotrichia |
US20020025317A1 (en) * | 2000-07-20 | 2002-02-28 | Schering Ag | Bispecific monoclonal antibodies to IL-12 and IL-18 |
AU2000270300A1 (en) * | 2000-09-13 | 2002-03-26 | Isis Innovation Limited | Use of phosphodiesterase inhibitors for the treatment of anorectal disorders |
EP1188438A1 (en) * | 2000-09-15 | 2002-03-20 | Warner-Lambert Company | Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production |
EP1199074A1 (en) * | 2000-09-15 | 2002-04-24 | Warner-Lambert Company | Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production |
KR100857376B1 (en) * | 2001-01-29 | 2008-09-05 | 라보라토리스 세로노 에스.에이. | Use of il-18 inhibitors for the treatment and/or prevention of heart disease |
EA009125B1 (en) * | 2001-05-16 | 2007-10-26 | Йеда Рисерч Энд Дивелопмент Ко., Лтд. | Use of il-18 inhibitors for the treatment and/or prevention diseases characteristic to the systemic inflammatory response syndrome |
PL222211B1 (en) | 2001-06-26 | 2016-07-29 | Amgen Fremont Inc | Antibodies to opgl |
SI1448205T1 (en) * | 2001-10-05 | 2011-07-29 | Zalicus Inc | Combinations for the treatment of immunoinflammatory disorders |
JP2003342196A (en) * | 2002-05-31 | 2003-12-03 | Mukku:Kk | Composition for intravenous injection, method of production for the same and its preparation |
BR0314713A (en) * | 2002-09-24 | 2005-07-26 | Combinatorx Inc | Processes and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines. |
WO2004028545A1 (en) * | 2002-09-25 | 2004-04-08 | Astrazeneca Ab | A COMBINATION OF A LONG-ACTING β2-AGONIST AND A GLUCOCORTICOSTEROID IN THE TREATMENT OF FIBROTIC DISEASES |
WO2004067006A1 (en) * | 2003-01-27 | 2004-08-12 | Pharmacia Corporation | Combination of a pde iv inhibitor and a tnf-alpha antagonist |
US20050100965A1 (en) | 2003-11-12 | 2005-05-12 | Tariq Ghayur | IL-18 binding proteins |
EP1752159A4 (en) * | 2004-05-17 | 2009-07-01 | Univ Keio | Medicinal composition and therapeutic method |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
US7887802B2 (en) | 2004-07-16 | 2011-02-15 | Atsuo Sekiyama | IL-18 receptor antagonist and pharmaceutical composition containing the antagonist |
US20070287689A1 (en) * | 2004-10-13 | 2007-12-13 | Kyowa Hakko Kogyo Co., Ltd. | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases |
BRPI0613034A8 (en) | 2005-07-14 | 2018-01-02 | Lipothera Inc | injectable formulation for fat tissue accumulation, injectable formulation and method for treating fat accumulation, and method for reducing fat tissue. |
PL2077830T3 (en) * | 2006-10-17 | 2013-04-30 | Lithera Inc | Methods, compositions, and formulations for the treatment of thyroid eye disease |
NZ578065A (en) | 2007-01-16 | 2012-09-28 | Abbott Lab | Methods for treating psoriasis with an antibody which binds to an epitope |
NZ598881A (en) | 2007-03-29 | 2013-11-29 | Abbvie Inc | Crystalline anti-human il-12 antibodies |
NZ587765A (en) | 2008-03-18 | 2013-02-22 | Abbott Lab | Methods for treating psoriasis |
US9132084B2 (en) | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
CA2815374A1 (en) | 2010-11-24 | 2012-06-07 | Lithera, Inc. | Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
WO2015063669A1 (en) | 2013-10-30 | 2015-05-07 | Wockhardt Limited | Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof |
AU2022353032A1 (en) * | 2021-09-22 | 2024-03-28 | Iolyx Therapeutics, Inc. | Methods of treating ocular inflammatory diseases |
Family Cites Families (7)
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US3320125A (en) * | 1964-04-28 | 1967-05-16 | Merck & Co Inc | Inhalation aerosol composition |
DK0416950T3 (en) * | 1989-09-08 | 1993-10-11 | Glaxo Group Ltd | medications |
IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant |
GB9202519D0 (en) * | 1992-02-06 | 1992-03-25 | Glaxo Group Ltd | Medicaments |
MX9304585A (en) * | 1992-07-31 | 1994-03-31 | Glaxo Group Ltd | PHARMACEUTICAL FORMULATION IN AEROSOL, CAN SUITABLE TO RELEASE THE FORMULATION AND INHALER OF DOSE DOSE THAT COMPRISES THE CAN. |
GB9426252D0 (en) * | 1994-12-24 | 1995-02-22 | Glaxo Group Ltd | Pharmaceutical composition |
GEP20002266B (en) * | 1995-04-14 | 2000-10-25 | Glaxo Wellcome Inc | Metered Dose Inhaler, the Inhaler System Comprising the Same and Method for Treatment of Respiratory Disturbances |
-
1998
- 1998-03-12 PL PL98336464A patent/PL336464A1/en unknown
- 1998-03-12 AU AU67604/98A patent/AU734756B2/en not_active Ceased
- 1998-03-12 JP JP54063398A patent/JP2002504091A/en active Pending
- 1998-03-12 NZ NZ337769A patent/NZ337769A/en unknown
- 1998-03-12 SI SI9820032A patent/SI20110A/en unknown
- 1998-03-12 CN CN98805124A patent/CN1269722A/en active Pending
- 1998-03-12 ES ES98912929T patent/ES2146192T1/en active Pending
- 1998-03-12 CA CA002282845A patent/CA2282845A1/en not_active Abandoned
- 1998-03-12 DE DE0998300T patent/DE998300T1/en active Pending
- 1998-03-12 EP EP98912929A patent/EP0998300A1/en not_active Withdrawn
- 1998-03-12 KR KR1019997008524A patent/KR20000076420A/en not_active Application Discontinuation
- 1998-03-12 BR BR9810409-8A patent/BR9810409A/en not_active IP Right Cessation
- 1998-03-12 SK SK1221-99A patent/SK122199A3/en unknown
- 1998-03-12 TR TR1999/02615T patent/TR199902615T2/en unknown
- 1998-03-12 WO PCT/US1998/004916 patent/WO1998041232A2/en not_active Application Discontinuation
- 1998-03-12 IL IL13181598A patent/IL131815A0/en unknown
- 1998-03-12 ID IDW991185A patent/ID22975A/en unknown
- 1998-03-12 HU HU0104439A patent/HUP0104439A3/en unknown
-
1999
- 1999-09-17 NO NO994506A patent/NO994506L/en unknown
- 1999-10-13 BG BG103808A patent/BG103808A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO1998041232A2 (en) | 1998-09-24 |
AU734756B2 (en) | 2001-06-21 |
SI20110A (en) | 2000-06-30 |
HUP0104439A2 (en) | 2002-04-29 |
DE998300T1 (en) | 2001-03-01 |
BG103808A (en) | 2000-07-31 |
HUP0104439A3 (en) | 2002-08-28 |
NO994506D0 (en) | 1999-09-17 |
WO1998041232A3 (en) | 2000-10-05 |
NO994506L (en) | 1999-11-17 |
NZ337769A (en) | 2002-09-27 |
CN1269722A (en) | 2000-10-11 |
ES2146192T1 (en) | 2000-08-01 |
EP0998300A1 (en) | 2000-05-10 |
CA2282845A1 (en) | 1998-09-24 |
PL336464A1 (en) | 2000-06-19 |
AU6760498A (en) | 1998-10-12 |
SK122199A3 (en) | 2000-12-11 |
KR20000076420A (en) | 2000-12-26 |
ID22975A (en) | 1999-12-23 |
BR9810409A (en) | 2000-08-22 |
JP2002504091A (en) | 2002-02-05 |
TR199902615T2 (en) | 2000-03-21 |
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