IL128230A0 - Method of screening active compounds - Google Patents

Method of screening active compounds

Info

Publication number
IL128230A0
IL128230A0 IL12823097A IL12823097A IL128230A0 IL 128230 A0 IL128230 A0 IL 128230A0 IL 12823097 A IL12823097 A IL 12823097A IL 12823097 A IL12823097 A IL 12823097A IL 128230 A0 IL128230 A0 IL 128230A0
Authority
IL
Israel
Prior art keywords
snom
vorrichtung
wirkstoff
active compounds
screening active
Prior art date
Application number
IL12823097A
Other versions
IL128230A (en
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of IL128230A0 publication Critical patent/IL128230A0/en
Publication of IL128230A publication Critical patent/IL128230A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01Q—SCANNING-PROBE TECHNIQUES OR APPARATUS; APPLICATIONS OF SCANNING-PROBE TECHNIQUES, e.g. SCANNING PROBE MICROSCOPY [SPM]
    • G01Q60/00—Particular types of SPM [Scanning Probe Microscopy] or microscopes; Essential components thereof
    • G01Q60/18—SNOM [Scanning Near-Field Optical Microscopy] or apparatus therefor, e.g. SNOM probes
    • G01Q60/20—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

Abstract

Verfahren zum Wirkstoff-Screening, wobei man den Wirkstoff über die mittels einer rasteroptischen Nahfeldmikroskopiervorrichtung (SNOM-Vorrichtung) beobachtbare Änderung eines Signals (S) nachweist, sowie dafür geeignete Einrichtung, umfassend die SNOM-Vorrichtung, eine Einzel- oder Mehrfachprobenaufnahmevorrichtung und eine Steuereinrichtung.
IL12823097A 1996-08-02 1997-07-30 Method of screening active compounds using a scanning near field optical microscopy instrument IL128230A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19631395A DE19631395A1 (en) 1996-08-02 1996-08-02 Drug screening process
PCT/EP1997/004152 WO1998005963A1 (en) 1996-08-02 1997-07-30 Active substance screening process

Publications (2)

Publication Number Publication Date
IL128230A0 true IL128230A0 (en) 1999-11-30
IL128230A IL128230A (en) 2002-02-10

Family

ID=7801706

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12823097A IL128230A (en) 1996-08-02 1997-07-30 Method of screening active compounds using a scanning near field optical microscopy instrument

Country Status (10)

Country Link
EP (1) EP0920625B1 (en)
JP (1) JP3748893B2 (en)
KR (1) KR20000029764A (en)
CN (1) CN1231728A (en)
AT (1) ATE200152T1 (en)
CA (1) CA2262506A1 (en)
CZ (1) CZ34899A3 (en)
DE (2) DE19631395A1 (en)
IL (1) IL128230A (en)
WO (1) WO1998005963A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876946A (en) * 1997-06-03 1999-03-02 Pharmacopeia, Inc. High-throughput assay
DE19915310A1 (en) * 1999-04-03 2000-10-05 Bayer Ag Diffusion-controlling sensor layer
US7214540B2 (en) 1999-04-06 2007-05-08 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
EP1701159A3 (en) * 1999-04-06 2007-07-25 University of Alabama Method for screening crystallization conditions in protein solution crystal growth
NZ514732A (en) * 1999-04-06 2004-01-30 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
KR100375105B1 (en) * 2000-09-08 2003-03-08 주식회사 셀텍 Apparatus for analyzing for a disease and virus in using Photo diode
US7670429B2 (en) 2001-04-05 2010-03-02 The California Institute Of Technology High throughput screening of crystallization of materials
KR101167649B1 (en) 2011-04-20 2012-07-20 한국과학기술원 Apparatus for analyzing single protein-protein interactions in whole cell lysates
CN112906754A (en) * 2021-01-26 2021-06-04 江苏大学 Surfactant identification method and device based on boiling heat exchange characteristics of surfactant solution

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69212062T2 (en) * 1991-04-30 1996-11-28 Matsushita Electric Ind Co Ltd Scanning scanning microscope, molecular processing method using the microscope and method for perceiving the DNA base arrangement
US5479024A (en) * 1994-08-11 1995-12-26 The Regents Of The University Of California Method and apparatus for performing near-field optical microscopy

Also Published As

Publication number Publication date
JP2000516706A (en) 2000-12-12
ATE200152T1 (en) 2001-04-15
CN1231728A (en) 1999-10-13
JP3748893B2 (en) 2006-02-22
EP0920625B1 (en) 2001-03-28
CZ34899A3 (en) 1999-11-17
CA2262506A1 (en) 1998-02-12
EP0920625A1 (en) 1999-06-09
IL128230A (en) 2002-02-10
WO1998005963A1 (en) 1998-02-12
KR20000029764A (en) 2000-05-25
DE59703240D1 (en) 2001-05-03
DE19631395A1 (en) 1998-02-05

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MM9K Patent not in force due to non-payment of renewal fees