IL117726A - Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane - Google Patents

Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane

Info

Publication number
IL117726A
IL117726A IL11772696A IL11772696A IL117726A IL 117726 A IL117726 A IL 117726A IL 11772696 A IL11772696 A IL 11772696A IL 11772696 A IL11772696 A IL 11772696A IL 117726 A IL117726 A IL 117726A
Authority
IL
Israel
Prior art keywords
tetraazacyclo
phenylenebis
tetradecane
methylene
bis
Prior art date
Application number
IL11772696A
Other languages
English (en)
Other versions
IL117726A0 (en
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of IL117726A0 publication Critical patent/IL117726A0/xx
Publication of IL117726A publication Critical patent/IL117726A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/18—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL11772696A 1995-03-30 1996-03-29 Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane IL117726A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/413,582 US5612478A (en) 1995-03-30 1995-03-30 Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane

Publications (2)

Publication Number Publication Date
IL117726A0 IL117726A0 (en) 1996-07-23
IL117726A true IL117726A (en) 2000-07-16

Family

ID=23637803

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11772696A IL117726A (en) 1995-03-30 1996-03-29 Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane

Country Status (12)

Country Link
US (3) US5612478A (no)
EP (1) EP0817777A1 (no)
JP (1) JPH11502830A (no)
KR (1) KR19980703464A (no)
AU (1) AU709426B2 (no)
CA (1) CA2216722A1 (no)
HU (1) HUP9802432A3 (no)
IL (1) IL117726A (no)
NO (1) NO307966B1 (no)
NZ (1) NZ303743A (no)
WO (1) WO1996030349A1 (no)
ZA (1) ZA962404B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612478A (en) * 1995-03-30 1997-03-18 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
US6365583B1 (en) 1999-02-02 2002-04-02 Anormed, Inc. Methods to enhance white blood cell count
US6482943B1 (en) * 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
CA2368801A1 (en) * 1999-04-30 2000-11-09 Slil Biomedical Corporation Conjugates as therapies for cancer and prostate diseases
EP1698629A3 (en) 1999-04-30 2006-11-29 Cellgate, Inc. Polyamines and their use in therapy
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
JP2002543126A (ja) * 1999-05-03 2002-12-17 スミスクライン・ビーチャム・コーポレイション Ｃｘｃｒ−４受容体アンタゴニスト−トロンボポエチン模倣物
US20030072715A1 (en) * 2000-08-02 2003-04-17 Benjamin Frydman Cyclic polyamine compounds for cancer therapy
PL359292A1 (en) 2000-09-29 2004-08-23 Anormed Inc. Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof
EP1337504A4 (en) * 2000-11-08 2005-10-05 Cellgate Inc NOVEL AMINO ACID CONJUGATES AND POLYAMINE ANALOGUES USEFUL AS ANTICANCING AGENTS
US6423481B1 (en) * 2001-01-23 2002-07-23 Eastman Kodak Company High speed photothermographic materials with combined chemical sensitizers and methods of using same
US7169750B2 (en) * 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
SI1411918T1 (sl) * 2001-07-31 2012-04-30 Genzyme Global S A R L Postopki za mobilizacijo progenitorskih/matičnih celic
US6982351B2 (en) * 2001-12-07 2006-01-03 Cellgate, Inc. Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
US6946015B2 (en) * 2003-06-26 2005-09-20 The Regents Of The University Of California Cross-linked polybenzimidazole membrane for gas separation
US6997971B1 (en) * 2004-07-28 2006-02-14 The Regents Of The University Of California Cross-linked polybenzimidazole membrane for gas separation
US20100035941A1 (en) * 2006-02-24 2010-02-11 Bridger Gary J Methods for increasing blood flow and/or promoting tissue regeneration
RU2638802C2 (ru) 2011-05-16 2017-12-15 Джензим Корпорейшн Применение антагонистов cxcr4
CN104211652B (zh) * 2014-08-27 2016-09-07 吉林大学 一种制备普乐沙福的方法
KR102398968B1 (ko) 2020-07-13 2022-05-17 (주) 엘피스셀테라퓨틱스 조혈 줄기세포의 가동을 위한 물질-p의 배합 요법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719041D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
WO1990007261A2 (en) * 1988-12-22 1990-07-12 The Dow Chemical Company Process for preparing mono-n-alkylated polyazamacrocycles
FR2644453A1 (fr) * 1989-03-20 1990-09-21 Centre Nat Rech Scient Procede de preparation de tetramines cycliques monofonctionnalisees
US5021409A (en) * 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
GB9126677D0 (en) * 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
US5326861A (en) * 1992-10-21 1994-07-05 Lever Brothers Company, Division Of Conopco, Inc. Preparation of organic macrocyclic compounds
US5612478A (en) * 1995-03-30 1997-03-18 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane

Also Published As

Publication number Publication date
NO307966B1 (no) 2000-06-26
US5612478A (en) 1997-03-18
US5801281A (en) 1998-09-01
JPH11502830A (ja) 1999-03-09
WO1996030349A1 (en) 1996-10-03
AU5013196A (en) 1996-10-16
IL117726A0 (en) 1996-07-23
NO974504D0 (no) 1997-09-29
US5756728A (en) 1998-05-26
HUP9802432A3 (en) 2000-01-28
NZ303743A (en) 1999-04-29
KR19980703464A (ko) 1998-11-05
AU709426B2 (en) 1999-08-26
EP0817777A1 (en) 1998-01-14
NO974504L (no) 1997-11-27
HUP9802432A2 (hu) 1999-04-28
ZA962404B (en) 1996-07-25
CA2216722A1 (en) 1996-10-03

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Legal Events

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FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees