IL117726A - Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane - Google Patents

Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane

Info

Publication number
IL117726A
IL117726A IL11772696A IL11772696A IL117726A IL 117726 A IL117726 A IL 117726A IL 11772696 A IL11772696 A IL 11772696A IL 11772696 A IL11772696 A IL 11772696A IL 117726 A IL117726 A IL 117726A
Authority
IL
Israel
Prior art keywords
tetraazacyclo
phenylenebis
tetradecane
methylene
bis
Prior art date
Application number
IL11772696A
Other languages
English (en)
Other versions
IL117726A0 (en
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of IL117726A0 publication Critical patent/IL117726A0/xx
Publication of IL117726A publication Critical patent/IL117726A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/36Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/18Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11772696A 1995-03-30 1996-03-29 Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane IL117726A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/413,582 US5612478A (en) 1995-03-30 1995-03-30 Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane

Publications (2)

Publication Number Publication Date
IL117726A0 IL117726A0 (en) 1996-07-23
IL117726A true IL117726A (en) 2000-07-16

Family

ID=23637803

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11772696A IL117726A (en) 1995-03-30 1996-03-29 Process for preparing 1,1'-¬1,4-phenylenebis-(methylene)-bis-1,4,8,11,tetraazacyclo-tetradecane

Country Status (12)

Country Link
US (3) US5612478A (da)
EP (1) EP0817777A1 (da)
JP (1) JPH11502830A (da)
KR (1) KR19980703464A (da)
AU (1) AU709426B2 (da)
CA (1) CA2216722A1 (da)
HU (1) HUP9802432A3 (da)
IL (1) IL117726A (da)
NO (1) NO307966B1 (da)
NZ (1) NZ303743A (da)
WO (1) WO1996030349A1 (da)
ZA (1) ZA962404B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612478A (en) * 1995-03-30 1997-03-18 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
US6365583B1 (en) 1999-02-02 2002-04-02 Anormed, Inc. Methods to enhance white blood cell count
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
MXPA01011008A (es) * 1999-04-30 2003-06-30 Slil Biomedical Corp Conjugados analogos de poliamina y conjugados de quinona novedosos como terapia para canceres y enfermedades de la prostata.
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
ES2269138T3 (es) 1999-04-30 2007-04-01 Cellgate, Inc. Poliaminas y su uso en terapia.
AU4692400A (en) * 1999-05-03 2000-11-17 Smithkline Beecham Corporation Cxcr-4 receptor antagonists - thrombopoietin mimetics
US20030072715A1 (en) * 2000-08-02 2003-04-17 Benjamin Frydman Cyclic polyamine compounds for cancer therapy
DE60136476D1 (de) * 2000-09-29 2008-12-18 Anormed Inc -stickstoffhaltigen zyklischen polyaminen und deren verbindungen
AU2002235126A1 (en) * 2000-11-08 2002-05-21 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
US6423481B1 (en) * 2001-01-23 2002-07-23 Eastman Kodak Company High speed photothermographic materials with combined chemical sensitizers and methods of using same
KR100996378B1 (ko) * 2001-07-31 2010-11-25 아노르메드 인코포레이티드 선조/줄기 세포를 이동시킴으로써 이식에 사용하기 위한 약제학적 조성물
US7169750B2 (en) * 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
CA2469354A1 (en) * 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
US6946015B2 (en) * 2003-06-26 2005-09-20 The Regents Of The University Of California Cross-linked polybenzimidazole membrane for gas separation
US6997971B1 (en) * 2004-07-28 2006-02-14 The Regents Of The University Of California Cross-linked polybenzimidazole membrane for gas separation
ES2497092T3 (es) * 2006-02-24 2014-09-22 Genzyme Corporation Procedimientos para el aumento del flujo sanguíneo y/o la estimulación de la regeneración de tejidos
BR112013029482A2 (pt) 2011-05-16 2016-08-09 Genzyme Corp utilização de antagonistas cxr4
CN104211652B (zh) * 2014-08-27 2016-09-07 吉林大学 一种制备普乐沙福的方法
KR102398968B1 (ko) 2020-07-13 2022-05-17 (주) 엘피스셀테라퓨틱스 조혈 줄기세포의 가동을 위한 물질-p의 배합 요법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719041D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
JP2930709B2 (ja) * 1988-12-22 1999-08-03 ザ ダウ ケミカル カンパニー モノ―n―アルキル化ポリアザ大員環の製造方法
FR2644453A1 (fr) * 1989-03-20 1990-09-21 Centre Nat Rech Scient Procede de preparation de tetramines cycliques monofonctionnalisees
US5021409A (en) * 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
GB9126677D0 (en) * 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
US5326861A (en) * 1992-10-21 1994-07-05 Lever Brothers Company, Division Of Conopco, Inc. Preparation of organic macrocyclic compounds
US5612478A (en) * 1995-03-30 1997-03-18 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane

Also Published As

Publication number Publication date
KR19980703464A (ko) 1998-11-05
CA2216722A1 (en) 1996-10-03
US5612478A (en) 1997-03-18
EP0817777A1 (en) 1998-01-14
AU5013196A (en) 1996-10-16
HUP9802432A2 (hu) 1999-04-28
NZ303743A (en) 1999-04-29
ZA962404B (en) 1996-07-25
WO1996030349A1 (en) 1996-10-03
JPH11502830A (ja) 1999-03-09
US5801281A (en) 1998-09-01
NO307966B1 (no) 2000-06-26
NO974504L (no) 1997-11-27
US5756728A (en) 1998-05-26
AU709426B2 (en) 1999-08-26
NO974504D0 (no) 1997-09-29
HUP9802432A3 (en) 2000-01-28
IL117726A0 (en) 1996-07-23

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees