IL116646A - Antifungal fusacandins, process for their preparation, pharmaceutical compositions containing them and uses thereof - Google Patents
Antifungal fusacandins, process for their preparation, pharmaceutical compositions containing them and uses thereofInfo
- Publication number
- IL116646A IL116646A IL11664696A IL11664696A IL116646A IL 116646 A IL116646 A IL 116646A IL 11664696 A IL11664696 A IL 11664696A IL 11664696 A IL11664696 A IL 11664696A IL 116646 A IL116646 A IL 116646A
- Authority
- IL
- Israel
- Prior art keywords
- aryl
- pharmaceutical compositions
- fusacandins
- antifungal
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229940121375 antifungal agent Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229930187800 Fusacandin Natural products 0.000 title 1
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 C2-C12-alkyl Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000005418 aryl aryl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000004362 fungal culture Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pest Control & Pesticides (AREA)
- Biotechnology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pretreatment Of Seeds And Plants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/370,934 US5585251A (en) | 1995-01-10 | 1995-01-10 | Fungal isolates, fusacandins |
| US08/548,803 US5773421A (en) | 1995-01-10 | 1995-12-21 | Antifungal fusacandins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL116646A0 IL116646A0 (en) | 1996-05-14 |
| IL116646A true IL116646A (en) | 2001-08-26 |
Family
ID=27005171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11664696A IL116646A (en) | 1995-01-10 | 1996-01-01 | Antifungal fusacandins, process for their preparation, pharmaceutical compositions containing them and uses thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5773421A (da) |
| EP (1) | EP0802920B1 (da) |
| JP (1) | JPH11500307A (da) |
| AT (1) | ATE206431T1 (da) |
| AU (1) | AU706072B2 (da) |
| CA (1) | CA2208019A1 (da) |
| DE (1) | DE69615657T2 (da) |
| DK (1) | DK0802920T3 (da) |
| ES (1) | ES2164234T3 (da) |
| IL (1) | IL116646A (da) |
| PT (1) | PT802920E (da) |
| WO (1) | WO1996021670A2 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5863773A (en) * | 1997-09-30 | 1999-01-26 | Abbott Laboratories | Antifungal corynecandin |
| WO2000076556A2 (en) * | 1999-06-11 | 2000-12-21 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| JP2004536034A (ja) | 2001-01-08 | 2004-12-02 | ネオルクス コーポレイション | 治療的および診断的化合物、組成物および方法 |
| EP1458416A1 (en) | 2001-12-13 | 2004-09-22 | Dow Global Technologies Inc. | Treatment of osteomyelitis with radiopharmaceuticals |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2609611A1 (de) * | 1975-03-13 | 1976-09-23 | Ciba Geigy Ag | Verfahren zur herstellung eines neuen antibiotikums |
| US5008187A (en) * | 1988-12-01 | 1991-04-16 | Merck & Co., Inc. | Antifungal fermentation product |
| US5585251A (en) * | 1995-01-10 | 1996-12-17 | Abbott Laboratories | Fungal isolates, fusacandins |
-
1995
- 1995-12-21 US US08/548,803 patent/US5773421A/en not_active Expired - Fee Related
-
1996
- 1996-01-01 IL IL11664696A patent/IL116646A/xx not_active IP Right Cessation
- 1996-01-03 AT AT96903378T patent/ATE206431T1/de not_active IP Right Cessation
- 1996-01-03 PT PT96903378T patent/PT802920E/pt unknown
- 1996-01-03 JP JP8521765A patent/JPH11500307A/ja active Pending
- 1996-01-03 DE DE69615657T patent/DE69615657T2/de not_active Expired - Fee Related
- 1996-01-03 ES ES96903378T patent/ES2164234T3/es not_active Expired - Lifetime
- 1996-01-03 WO PCT/US1996/000225 patent/WO1996021670A2/en not_active Ceased
- 1996-01-03 CA CA002208019A patent/CA2208019A1/en not_active Abandoned
- 1996-01-03 DK DK96903378T patent/DK0802920T3/da active
- 1996-01-03 AU AU47484/96A patent/AU706072B2/en not_active Ceased
- 1996-01-03 EP EP96903378A patent/EP0802920B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996021670A2 (en) | 1996-07-18 |
| DE69615657T2 (de) | 2002-08-08 |
| ATE206431T1 (de) | 2001-10-15 |
| EP0802920B1 (en) | 2001-10-04 |
| AU4748496A (en) | 1996-07-31 |
| US5773421A (en) | 1998-06-30 |
| JPH11500307A (ja) | 1999-01-12 |
| PT802920E (pt) | 2002-03-28 |
| DK0802920T3 (da) | 2002-01-21 |
| ES2164234T3 (es) | 2002-02-16 |
| MX9705136A (es) | 1997-10-31 |
| CA2208019A1 (en) | 1996-07-18 |
| IL116646A0 (en) | 1996-05-14 |
| AU706072B2 (en) | 1999-06-10 |
| WO1996021670A3 (en) | 1996-09-12 |
| DE69615657D1 (de) | 2001-11-08 |
| EP0802920A2 (en) | 1997-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |