IL112244A0 - Novel inhibitor - Google Patents

Novel inhibitor

Info

Publication number
IL112244A0
IL112244A0 IL11224495A IL11224495A IL112244A0 IL 112244 A0 IL112244 A0 IL 112244A0 IL 11224495 A IL11224495 A IL 11224495A IL 11224495 A IL11224495 A IL 11224495A IL 112244 A0 IL112244 A0 IL 112244A0
Authority
IL
Israel
Prior art keywords
novel inhibitor
inhibitor
novel
Prior art date
Application number
IL11224495A
Original Assignee
Ciba Geigy Ag
Ucp Gen Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag, Ucp Gen Pharma Ag filed Critical Ciba Geigy Ag
Publication of IL112244A0 publication Critical patent/IL112244A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/102—Plasmid DNA for yeast

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Water Supply & Treatment (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
IL11224495A 1994-01-07 1995-01-04 Novel inhibitor IL112244A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94810006 1994-01-07

Publications (1)

Publication Number Publication Date
IL112244A0 true IL112244A0 (en) 1995-03-30

Family

ID=8218193

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11224495A IL112244A0 (en) 1994-01-07 1995-01-04 Novel inhibitor

Country Status (9)

Country Link
US (1) US5861377A (en)
JP (1) JPH0841098A (en)
KR (1) KR950032284A (en)
AU (1) AU701136B2 (en)
CA (1) CA2139612A1 (en)
IL (1) IL112244A0 (en)
NZ (1) NZ270194A (en)
SG (1) SG49610A1 (en)
ZA (1) ZA9570B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358928B1 (en) 1999-11-22 2002-03-19 Enzyme Systems Products Peptidyl sulfonyl imidazolides as selective inhibitors of serine proteases
CN101095697A (en) * 2006-06-28 2008-01-02 李振国 Extractive of bdella and/or lumbricus with the molecular weight below 5800 dalton
CN101512001A (en) * 2006-07-14 2009-08-19 诺维信股份有限公司 Methods for increasing expression of genes in a fungal cell
JP2018093806A (en) * 2016-12-14 2018-06-21 国立大学法人山口大学 Method for excessive expressing of protein in yeast

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588587A (en) * 1983-03-01 1986-05-13 Pennsylvania Hospital Method of treatment to inhibit metastasis
DE3438296A1 (en) * 1984-04-18 1985-11-07 Hoechst Ag, 6230 Frankfurt NEW POLYPEPTIDES WITH A BLOOD-CLOTHING EFFECT, METHOD FOR THE PRODUCTION OR THEIR RECOVERY, THEIR USE AND THE CONTAINERS THEREOF
US4835253A (en) * 1987-04-03 1989-05-30 The University Hospital Specific inhibitors of tissue kallikrein
NL8900943A (en) * 1989-04-14 1990-11-01 Euro Biopharm Technology B V PROTEASE INHIBITOR.
AU624962B2 (en) * 1989-06-20 1992-06-25 Merrell Dow Pharmaceuticals Inc. Ghilanten: antimetastatic principle from the south american leech, haementeria ghilanii
US5189019A (en) * 1990-04-23 1993-02-23 Merck & Co., Inc. Antistasin derived anticoagulant protein
EP0693925B1 (en) * 1993-04-09 2002-02-13 Bio-Technology General Corporation Production of a recombinant factor xa inhibitor of leech hirudo medicinalis
EP0662514A1 (en) * 1994-01-07 1995-07-12 Ciba-Geigy Ag Hirustasin, an antistasin type serine proteinase inhibitor from Hiruda

Also Published As

Publication number Publication date
KR950032284A (en) 1995-12-20
JPH0841098A (en) 1996-02-13
CA2139612A1 (en) 1995-07-08
AU8159594A (en) 1995-07-20
SG49610A1 (en) 2001-02-20
US5861377A (en) 1999-01-19
AU701136B2 (en) 1999-01-21
NZ270194A (en) 1996-05-28
ZA9570B (en) 1995-07-07

Similar Documents

Publication Publication Date Title
PL321759A1 (en) Novel thrombosin inhibitors
DE69533256D1 (en) Chimäre komplement inhibitor proteine
ZA9510554B (en) Substituted 1H-imidazoles
GB9416078D0 (en) Ice inhibitor
EP0778836A4 (en) Substituted 9-alkyladenines
GB2291066B (en) Embossing inhibitor
HU9502378D0 (en) Substituted biphenyl-oxazolinones
ZA954095B (en) Substituted 3-phenylpyrazoles
HU9503783D0 (en) Squvalen syntetase inhibitors
ZA956011B (en) Substituted triazolylmethylphenylnaphthyridones
ZA954546B (en) Substituted 3-phenylpyrazoles
DE69523450D1 (en) Inhibitor
SG73418A1 (en) Novel dihydrodibenzoquinolinediones
SG49610A1 (en) Novel inhibitor
AU122938S (en) Breadbox
IL113603A0 (en) Novel substituted benzimidalozes
ZA951092B (en) Substituted oxazacycloalkenes
GB9413054D0 (en) Complement inhibitor
CA73835S (en) Air-purifier
CA73798S (en) Air-purifier
SG33449A1 (en) Novel pyrrolocarbazoles
GB9410425D0 (en) Novel bishydrazides
GB9410400D0 (en) Novel bishydrazides
GB9717893D0 (en) Inhibitor
GB9707219D0 (en) Inhibitor