GB9416078D0 - Ice inhibitor - Google Patents

Ice inhibitor

Info

Publication number
GB9416078D0
GB9416078D0 GB9416078A GB9416078A GB9416078D0 GB 9416078 D0 GB9416078 D0 GB 9416078D0 GB 9416078 A GB9416078 A GB 9416078A GB 9416078 A GB9416078 A GB 9416078A GB 9416078 D0 GB9416078 D0 GB 9416078D0
Authority
GB
United Kingdom
Prior art keywords
ice inhibitor
inhibitor
ice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9416078A
Other versions
GB2292149A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring Research Ltd
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Ferring Research Ltd
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Research Ltd, Yamanouchi Pharmaceutical Co Ltd filed Critical Ferring Research Ltd
Priority to GB9416078A priority Critical patent/GB2292149A/en
Publication of GB9416078D0 publication Critical patent/GB9416078D0/en
Publication of GB2292149A publication Critical patent/GB2292149A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
GB9416078A 1994-08-09 1994-08-09 Peptide inhibitors of pro-interleukin-1beta converting enzyme Withdrawn GB2292149A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9416078A GB2292149A (en) 1994-08-09 1994-08-09 Peptide inhibitors of pro-interleukin-1beta converting enzyme

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9416078A GB2292149A (en) 1994-08-09 1994-08-09 Peptide inhibitors of pro-interleukin-1beta converting enzyme

Publications (2)

Publication Number Publication Date
GB9416078D0 true GB9416078D0 (en) 1994-09-28
GB2292149A GB2292149A (en) 1996-02-14

Family

ID=10759625

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9416078A Withdrawn GB2292149A (en) 1994-08-09 1994-08-09 Peptide inhibitors of pro-interleukin-1beta converting enzyme

Country Status (1)

Country Link
GB (1) GB2292149A (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0946502B1 (en) * 1996-10-11 2002-12-18 Warner-Lambert Company Sulfonamide interleukin-beta converting enzyme inhibitors
ATE267168T1 (en) * 1997-11-24 2004-06-15 Merck & Co Inc BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS
US6645939B1 (en) 1997-11-24 2003-11-11 Merck & Co., Inc. Substituted β-alanine derivatives as cell adhesion inhibitors
KR100928878B1 (en) * 1998-03-19 2009-11-30 버텍스 파마슈티칼스 인코포레이티드 Inhibitors of caspases
EP1129108A4 (en) * 1998-10-06 2002-01-09 Smithkline Beecham Corp Caspases and apoptosis
US6242422B1 (en) * 1998-10-22 2001-06-05 Idun Pharmacueticals, Inc. (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases
US7157430B2 (en) 1998-10-22 2007-01-02 Idun Pharmaceuticals, Inc. (Substituted)acyl dipeptidyl inhibitors of the ICE/CED-3 family of cysteine proteases
AR026748A1 (en) 1999-12-08 2003-02-26 Vertex Pharma A CASPASE INHIBITING COMPOUND, A PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, A METHOD FOR THE SYNTHESIS OF THE SAME AND AN INTERMEDIATE COMPOUND PARADICHA SYNTHESIS
US6790989B2 (en) 2000-01-13 2004-09-14 Idun Pharmaceuticals, Inc. Inhibitors of the ICE/ced-3 family of cysteine proteases
US6515173B1 (en) 2000-01-13 2003-02-04 Idun Pharmaceuticals, Inc. Inhibitors of the ICE/ced-3 family of cysteine proteases
US6525024B1 (en) 2000-04-17 2003-02-25 Idun Pharmaceuticals, Inc. Inhibitors of the ICE/ced-3 family of cysteine proteases
PE20011350A1 (en) 2000-05-19 2002-01-15 Vertex Pharma PROPHARMAC OF AN INHIBITOR OF INTERLEUKIN-1ß CONVERTER ENZYME (ICE)
US20020052323A1 (en) * 2000-08-30 2002-05-02 Jinhai Wang Quinoline-(C=O)-(multiple amino acids)-leaving group compounds for pharmaceutical compositions and reagents
JP2004521080A (en) 2000-09-08 2004-07-15 メルク フロスト カナダ アンド カンパニー Gamma-keto acid dipeptides as caspase-3 inhibitors
WO2003072528A2 (en) * 2002-02-08 2003-09-04 Idun Pharmaceuticals, Inc. (substituted)acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
PE20050159A1 (en) 2003-05-27 2005-04-19 Vertex Pharma DERIVATIVES OF 3- [2- (3-AMINO-2-OXO-2H-PYRIDIN-1-IL) -ACETILAMINO] -4-OXO-PENTANOICO AS CASPASE INHIBITORS
WO2005085245A1 (en) 2004-03-08 2005-09-15 Prosidion Limited Pyrrolopyridine-2-carboxylic acid hydrazides
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
KR20070083484A (en) 2004-07-14 2007-08-24 피티씨 테라퓨틱스, 인크. Methods for treating hepatitis c
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7645881B2 (en) 2004-07-22 2010-01-12 Ptc Therapeutics, Inc. Methods for treating hepatitis C
WO2006045096A2 (en) 2004-10-20 2006-04-27 Resverlogix Corp. Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
US20090099176A1 (en) 2004-12-02 2009-04-16 Thomas Martin Krulle Pyrrolopyridine-2-carboxylic acid amides
MY144590A (en) 2005-07-11 2011-10-14 Wyeth Corp Glutamate aggrecanase inhibitors
CN101365446B (en) 2005-07-29 2013-05-22 雷斯弗洛吉克斯公司 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
TW200740729A (en) 2005-10-13 2007-11-01 Wyeth Corp Methods for preparing glutamic acid derivatives
EP2118074B1 (en) 2007-02-01 2014-01-22 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
DK2346837T3 (en) 2008-06-26 2015-04-20 Resverlogix Corp Methods for preparing quinazolinone derivatives
CA2747417C (en) 2009-01-08 2017-01-03 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
BRPI1014956B8 (en) 2009-04-22 2021-05-25 Resverlogix Corp anti-inflammatory agents
EP2655331A1 (en) 2010-12-23 2013-10-30 Pfizer Inc Glucagon receptor modulators
GEP20156351B (en) 2011-02-08 2015-08-25 Pfizer Glucagon receptor modulator
KR20140023441A (en) 2011-07-22 2014-02-26 화이자 인코포레이티드 Quinolinyl glucagon receptor modulators
DK2773354T3 (en) 2011-11-01 2019-08-05 Resverlogix Corp ORAL FORMS WITH IMMEDIATE RELEASE FOR SUBSTITUTED QUINAZOLINONS
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
MX2015007921A (en) 2012-12-21 2016-03-03 Zenith Epigenetics Corp Novel heterocyclic compounds as bromodomain inhibitors.
CA2977308A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
PL3464336T3 (en) 2016-06-01 2022-05-16 Athira Pharma, Inc. Compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9123326D0 (en) * 1991-11-04 1991-12-18 Sandoz Ltd Improvements in or relating to organic compounds
EP0547699A1 (en) * 1991-12-19 1993-06-23 Merck & Co. Inc. Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme
ES2118940T3 (en) * 1992-02-21 1998-10-01 Merck & Co Inc PEPTIDIL-DERIVATIVES USEFUL AS INHIBITORS OF THE CONVERTING ENZYME OF INTERLEUKIN-1 BETA.

Also Published As

Publication number Publication date
GB2292149A (en) 1996-02-14

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)