IL111906A0 - Combinatorial compound libraries and process for their production - Google Patents

Combinatorial compound libraries and process for their production

Info

Publication number
IL111906A0
IL111906A0 IL11190694A IL11190694A IL111906A0 IL 111906 A0 IL111906 A0 IL 111906A0 IL 11190694 A IL11190694 A IL 11190694A IL 11190694 A IL11190694 A IL 11190694A IL 111906 A0 IL111906 A0 IL 111906A0
Authority
IL
Israel
Prior art keywords
production
compound libraries
combinatorial compound
combinatorial
libraries
Prior art date
Application number
IL11190694A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL111906A0 publication Critical patent/IL111906A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11190694A 1993-12-09 1994-12-07 Combinatorial compound libraries and process for their production IL111906A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93810864 1993-12-09

Publications (1)

Publication Number Publication Date
IL111906A0 true IL111906A0 (en) 1995-03-15

Family

ID=8215084

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11190694A IL111906A0 (en) 1993-12-09 1994-12-07 Combinatorial compound libraries and process for their production

Country Status (9)

Country Link
EP (1) EP0733213A1 (xx)
JP (1) JPH09508355A (xx)
AU (1) AU1068295A (xx)
CA (1) CA2175078A1 (xx)
FI (1) FI962371A0 (xx)
HU (1) HUT75223A (xx)
IL (1) IL111906A0 (xx)
NO (1) NO962186L (xx)
WO (1) WO1995016209A1 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030392A1 (en) * 1995-03-28 1996-10-03 Novartis Ag Process for the production of combinatorial compound libraries
US6495314B1 (en) * 1995-09-29 2002-12-17 The Scripps Research Institute Process for characterizing proteins
US20030100007A1 (en) * 1995-12-18 2003-05-29 Howard Benjamin Methods for identifying compounds that bind to a target
US5866341A (en) * 1996-04-03 1999-02-02 Chugai Pharmaceutical Co., Ltd. Compositions and methods for screening drug libraries
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
DK1133558T4 (en) 1998-11-27 2016-05-17 Ucb Sa Compositions and methods for increasing bone mineralization
EP1071958A1 (en) * 1999-02-17 2001-01-31 Arcaris, Inc. Methods for substrate-ligand interaction screening
KR20020021779A (ko) * 1999-03-23 2002-03-22 바이오베이션 리미티드 단백질 단리 및 분석
WO2000066259A1 (en) 1999-05-05 2000-11-09 Ut-Battelle, Llc Method and apparatus for combinatorial chemistry
US7351540B1 (en) 2000-03-17 2008-04-01 Merck Patent Gmbh Protein isolation and analysis
WO2001086296A2 (en) * 2000-05-05 2001-11-15 Agilix Corporation Highly multiplexed reporter carrier systems
DE10117274B4 (de) * 2001-04-06 2005-03-03 Hte Ag The High Throughput Experimentation Company Verfahren zur Analyse und Archivierung von wenigstens einer Materialbibliothek
EP1446500B1 (en) 2001-05-08 2008-08-20 Darwin Molecular Corporation A method for regulating immune function in primates using the foxp3 protein
US20030124595A1 (en) * 2001-11-06 2003-07-03 Lizardi Paul M. Sensitive coded detection systems
EP2258724A1 (en) 2002-11-21 2010-12-08 Celltech R & D, Inc. Modulating immune responses using multimerized anti-CD83 antibodies
EP1731908B1 (en) * 2004-03-31 2010-09-01 Kazuo Shinya Method of biosubstance trapping, structural analysis or/and identification with use of a labeling substance
CA3217862A1 (en) 2021-05-05 2022-11-10 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK105289A (da) * 1988-03-04 1989-09-05 Univ Alabama Peptidaekvivalenter til ikke-peptider og fremgangsmaader til udformning af disse
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
AU656947B2 (en) * 1991-02-04 1995-02-23 Akzo N.V. Factor IIa inhibitors
AU669489B2 (en) * 1991-09-18 1996-06-13 Affymax Technologies N.V. Method of synthesizing diverse collections of oligomers

Also Published As

Publication number Publication date
JPH09508355A (ja) 1997-08-26
NO962186D0 (no) 1996-05-29
FI962371A (fi) 1996-06-07
WO1995016209A1 (en) 1995-06-15
EP0733213A1 (en) 1996-09-25
AU1068295A (en) 1995-06-27
CA2175078A1 (en) 1995-06-15
HUT75223A (en) 1997-04-28
FI962371A0 (fi) 1996-06-07
NO962186L (no) 1996-05-29
HU9601588D0 (en) 1996-08-28

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