IL111018A0 - triaryl ethylene derivatives and pharmaceutical compositions containing them - Google Patents

triaryl ethylene derivatives and pharmaceutical compositions containing them

Info

Publication number
IL111018A0
IL111018A0 IL11101894A IL11101894A IL111018A0 IL 111018 A0 IL111018 A0 IL 111018A0 IL 11101894 A IL11101894 A IL 11101894A IL 11101894 A IL11101894 A IL 11101894A IL 111018 A0 IL111018 A0 IL 111018A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
ethylene derivatives
triaryl
triaryl ethylene
Prior art date
Application number
IL11101894A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/259,797 external-priority patent/US5525633A/en
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL111018A0 publication Critical patent/IL111018A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11101894A 1993-09-24 1994-09-21 triaryl ethylene derivatives and pharmaceutical compositions containing them IL111018A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12661493A 1993-09-24 1993-09-24
US08/259,797 US5525633A (en) 1993-09-24 1994-06-15 Triaryl-ethylene derivatives

Publications (1)

Publication Number Publication Date
IL111018A0 true IL111018A0 (en) 1994-11-28

Family

ID=26824862

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11101894A IL111018A0 (en) 1993-09-24 1994-09-21 triaryl ethylene derivatives and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US5684004A (da)
EP (1) EP0720597B1 (da)
JP (1) JPH09503761A (da)
CN (1) CN1131415A (da)
AT (1) ATE165594T1 (da)
AU (1) AU678535B2 (da)
CA (1) CA2171728C (da)
DE (1) DE69409961T2 (da)
DK (1) DK0720597T3 (da)
ES (1) ES2115975T3 (da)
FI (1) FI961339A0 (da)
HU (1) HUT75933A (da)
IL (1) IL111018A0 (da)
NO (1) NO306292B1 (da)
NZ (1) NZ273433A (da)
PL (1) PL177833B1 (da)
WO (1) WO1995008528A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1099093A (en) * 1965-09-03 1968-01-17 Ici Ltd Alkene derivatives
DE2860900D1 (en) * 1977-08-22 1981-11-05 Ici Plc Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE69409961D1 (de) 1998-06-04
NZ273433A (en) 1997-11-24
AU678535B2 (en) 1997-05-29
HUT75933A (en) 1997-05-28
CA2171728C (en) 2001-11-13
NO961204D0 (no) 1996-03-25
HU9600727D0 (en) 1996-05-28
WO1995008528A1 (en) 1995-03-30
NO961204L (no) 1996-03-25
AU7670794A (en) 1995-04-10
DK0720597T3 (da) 1998-10-07
DE69409961T2 (de) 1998-09-10
EP0720597B1 (en) 1998-04-29
PL313594A1 (en) 1996-07-08
ATE165594T1 (de) 1998-05-15
JPH09503761A (ja) 1997-04-15
EP0720597A1 (en) 1996-07-10
US5684004A (en) 1997-11-04
CN1131415A (zh) 1996-09-18
PL177833B1 (pl) 2000-01-31
FI961339A (fi) 1996-03-22
FI961339A0 (fi) 1996-03-22
CA2171728A1 (en) 1995-03-30
ES2115975T3 (es) 1998-07-01
NO306292B1 (no) 1999-10-18

Similar Documents

Publication Publication Date Title
IL128425A0 (en) Taxane derivatives their preparation and pharmaceutical compositions containing them
TW272195B (da)
IL113812A0 (en) Copolymer-1, pharmaceutical compositions containing it and its use
IL109720A (en) N-alkylthio polyamine derivatives and radioprotective compositions containing them
MX9804588A (es) Uso de composiciones que comprenden blanqueador de halogeno para suavidad mejorada a la piel.
DE69625354D1 (de) Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen
CA2152771A1 (en) 7-o-ethers of taxane derivatives
MY120683A (en) New phenylamidine derivatives, processes for their preparation and their use as pharmaceuticals.
IL111018A0 (en) triaryl ethylene derivatives and pharmaceutical compositions containing them
IL128500A (en) SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA[b] BENZOFURANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
AU6849198A (en) Neurotrypsin
MX9700854A (es) Derivados de azabicicloheptano n-substituidos utiles como neurolepticos.
EP0457127A3 (en) Spermicidal coating
MY117392A (en) Monocyclic compounds with four bifunctional residues having nk-2 antagonist action
TWI231815B (en) Glycopeptide derivatives and pharmaceutical compositions containing the same for use as antibacterial agents
MX9701726A (es) Recipiente con componentes de vacuna secados por congelacion.
UA16247A1 (uk) N-(3-ХЛОРО-1,4-HАФТОХІHОHІЛ-2)-2-Д, alРha-АСПАРАГІHОВУ КИСЛОТА, ЩО ПРОЯВЛЯЄ КАРДІОСТИМУЛЮЮЧІ ВЛАСТИВОСТІ
CA2234611A1 (en) New phenylamidine derivatives, processes for preparing them and their use as pharmaceutical compositions
CA2156908A1 (en) C9 taxane derivatives and pharmaceutical compositions containing them
CA2242097A1 (en) Imidazotriazolopyrimidines, process for preparing them and their use as pharmaceutical compositions