CA2156908A1 - C9 taxane derivatives and pharmaceutical compositions containing them - Google Patents
C9 taxane derivatives and pharmaceutical compositions containing themInfo
- Publication number
- CA2156908A1 CA2156908A1 CA002156908A CA2156908A CA2156908A1 CA 2156908 A1 CA2156908 A1 CA 2156908A1 CA 002156908 A CA002156908 A CA 002156908A CA 2156908 A CA2156908 A CA 2156908A CA 2156908 A1 CA2156908 A1 CA 2156908A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- taxane derivatives
- substituents
- taxane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Abstract
Taxane derivatives, useful as anti-tumor and anti-leukenia agents, having alternative C9 substituents wherein the substituents are selected from a group consisting of hydrogen, hydroxy, protected hydroxy and acyloxy.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2697393A | 1993-03-05 | 1993-03-05 | |
| US08/026,978 | 1993-03-05 | ||
| US3485293A | 1993-03-22 | 1993-03-22 | |
| US08/034,852 | 1993-03-22 | ||
| US9508793A | 1993-07-20 | 1993-07-20 | |
| US08/095,087 | 1993-07-20 | ||
| PCT/US1994/002210 WO1994020088A1 (en) | 1993-03-05 | 1994-03-01 | C9 taxane derivatives and pharmaceutical compositions containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2156908A1 true CA2156908A1 (en) | 1994-09-15 |
| CA2156908C CA2156908C (en) | 2001-10-02 |
Family
ID=27362897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002156908A Expired - Fee Related CA2156908C (en) | 1993-03-05 | 1994-03-01 | C9 taxane derivatives and pharmaceutical compositions containing them |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2156908C (en) |
-
1994
- 1994-03-01 CA CA002156908A patent/CA2156908C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2156908C (en) | 2001-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |