IL103758A - נוגדנים חד-שבטיים ספציפיים לסרטן - Google Patents
נוגדנים חד-שבטיים ספציפיים לסרטןInfo
- Publication number
- IL103758A IL103758A IL10375892A IL10375892A IL103758A IL 103758 A IL103758 A IL 103758A IL 10375892 A IL10375892 A IL 10375892A IL 10375892 A IL10375892 A IL 10375892A IL 103758 A IL103758 A IL 103758A
- Authority
- IL
- Israel
- Prior art keywords
- cells
- tumor
- human
- monoclonal antibodies
- amino acid
- Prior art date
Links
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- 238000002955 isolation Methods 0.000 description 1
- 229960003350 isoniazid Drugs 0.000 description 1
- QRXWMOHMRWLFEY-UHFFFAOYSA-N isoniazide Chemical compound NNC(=O)C1=CC=NC=C1 QRXWMOHMRWLFEY-UHFFFAOYSA-N 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 201000005249 lung adenocarcinoma Diseases 0.000 description 1
- 208000018555 lymphatic system disease Diseases 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 201000001441 melanoma Diseases 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 206010061289 metastatic neoplasm Diseases 0.000 description 1
- 230000011278 mitosis Effects 0.000 description 1
- 229940118665 mumps skin test antigen Drugs 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 231100001221 nontumorigenic Toxicity 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 238000011580 nude mouse model Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 229940043515 other immunoglobulins in atc Drugs 0.000 description 1
- 230000002611 ovarian Effects 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical group 0.000 description 1
- 238000003752 polymerase chain reaction Methods 0.000 description 1
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- 238000000746 purification Methods 0.000 description 1
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- 238000005215 recombination Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 206010038038 rectal cancer Diseases 0.000 description 1
- 201000001275 rectum cancer Diseases 0.000 description 1
- 238000001226 reprecipitation Methods 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 231100000004 severe toxicity Toxicity 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 208000000587 small cell lung carcinoma Diseases 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000037439 somatic mutation Effects 0.000 description 1
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- 210000001541 thymus gland Anatomy 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
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- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80730091A | 1991-12-13 | 1991-12-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL103758A0 IL103758A0 (en) | 1993-04-04 |
| IL103758A true IL103758A (he) | 1998-07-15 |
Family
ID=25196057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10375892A IL103758A (he) | 1991-12-13 | 1992-11-16 | נוגדנים חד-שבטיים ספציפיים לסרטן |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0546634A3 (he) |
| JP (1) | JP3539985B2 (he) |
| KR (1) | KR930013103A (he) |
| AU (1) | AU651261B2 (he) |
| CA (1) | CA2083542A1 (he) |
| FI (1) | FI925638A (he) |
| HU (1) | HU218081B (he) |
| IL (1) | IL103758A (he) |
| NO (1) | NO924803L (he) |
| NZ (1) | NZ245443A (he) |
| TW (1) | TW271450B (he) |
| ZA (1) | ZA928880B (he) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5198704B2 (ja) | 2000-03-03 | 2013-05-15 | メディミューン リミティド | エオタキシンに対するヒト抗体及びそれらの使用 |
| US6946546B2 (en) | 2000-03-06 | 2005-09-20 | Cambridge Antibody Technology Limited | Human antibodies against eotaxin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4322879A (en) * | 1978-01-11 | 1979-07-19 | Massachusetts General Hospital, The | Producing antibodies |
| US4172124A (en) | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
| US4828991A (en) | 1984-01-31 | 1989-05-09 | Akzo N.V. | Tumor specific monoclonal antibodies |
| NZ210867A (en) * | 1984-01-31 | 1989-01-06 | Litton Bionetics Inc | Tumour-specific monoclonal antibodies, production thereof and use |
| US4997762A (en) | 1984-01-31 | 1991-03-05 | Akzo N.V. | Tumor associated monocoloal antibodies derived from human B-cell line |
| ATE137674T1 (de) * | 1987-07-02 | 1996-05-15 | Akzo Nobel Nv | Von mca 16-88 erkanntes antigen |
-
1992
- 1992-11-16 IL IL10375892A patent/IL103758A/he not_active IP Right Cessation
- 1992-11-17 ZA ZA928880A patent/ZA928880B/xx unknown
- 1992-11-23 TW TW081109353A patent/TW271450B/zh active
- 1992-11-23 CA CA002083542A patent/CA2083542A1/en not_active Abandoned
- 1992-12-09 EP EP19920203827 patent/EP0546634A3/en not_active Withdrawn
- 1992-12-11 KR KR1019920023925A patent/KR930013103A/ko not_active Application Discontinuation
- 1992-12-11 FI FI925638A patent/FI925638A/fi unknown
- 1992-12-11 JP JP33196192A patent/JP3539985B2/ja not_active Expired - Fee Related
- 1992-12-11 HU HU9203932A patent/HU218081B/hu not_active IP Right Cessation
- 1992-12-11 NZ NZ245443A patent/NZ245443A/en active IP Right Revival
- 1992-12-11 NO NO92924803A patent/NO924803L/no not_active Application Discontinuation
- 1992-12-11 AU AU30088/92A patent/AU651261B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| FI925638A0 (fi) | 1992-12-11 |
| IL103758A0 (en) | 1993-04-04 |
| KR930013103A (ko) | 1993-07-21 |
| AU3008892A (en) | 1993-06-17 |
| CA2083542A1 (en) | 1993-06-14 |
| HU218081B (hu) | 2000-05-28 |
| ZA928880B (en) | 1993-08-12 |
| EP0546634A2 (en) | 1993-06-16 |
| NZ245443A (en) | 1995-12-21 |
| AU651261B2 (en) | 1994-07-14 |
| HU9203932D0 (en) | 1993-04-28 |
| NO924803L (no) | 1993-06-14 |
| TW271450B (he) | 1996-03-01 |
| FI925638A (fi) | 1993-06-14 |
| JP3539985B2 (ja) | 2004-07-07 |
| HUT65480A (en) | 1994-06-28 |
| NO924803D0 (no) | 1992-12-11 |
| EP0546634A3 (en) | 1994-09-21 |
| JPH05317042A (ja) | 1993-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |