IL101810A0 - Cholesterol lowering dioxabicyclo(3.2.1)octane derivatives and pharmaceutical compositions containing them - Google Patents

Cholesterol lowering dioxabicyclo(3.2.1)octane derivatives and pharmaceutical compositions containing them

Info

Publication number
IL101810A0
IL101810A0 IL101810A IL10181092A IL101810A0 IL 101810 A0 IL101810 A0 IL 101810A0 IL 101810 A IL101810 A IL 101810A IL 10181092 A IL10181092 A IL 10181092A IL 101810 A0 IL101810 A0 IL 101810A0
Authority
IL
Israel
Prior art keywords
dioxabicyclo
pharmaceutical compositions
compositions containing
cholesterol lowering
octane derivatives
Prior art date
Application number
IL101810A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL101810A0 publication Critical patent/IL101810A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL101810A 1991-05-10 1992-05-08 Cholesterol lowering dioxabicyclo(3.2.1)octane derivatives and pharmaceutical compositions containing them IL101810A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69876691A 1991-05-10 1991-05-10
US80560291A 1991-12-09 1991-12-09
US86674992A 1992-04-15 1992-04-15

Publications (1)

Publication Number Publication Date
IL101810A0 true IL101810A0 (en) 1992-12-30

Family

ID=27418673

Family Applications (1)

Application Number Title Priority Date Filing Date
IL101810A IL101810A0 (en) 1991-05-10 1992-05-08 Cholesterol lowering dioxabicyclo(3.2.1)octane derivatives and pharmaceutical compositions containing them

Country Status (7)

Country Link
EP (1) EP0512865A3 (de)
AU (1) AU1908292A (de)
CA (1) CA2109523A1 (de)
IE (1) IE921492A1 (de)
IL (1) IL101810A0 (de)
WO (1) WO1992020336A2 (de)
YU (1) YU49292A (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256689A (en) * 1991-05-10 1993-10-26 Merck & Co., Inc. Cholesterol lowering compounds
US5364948A (en) * 1991-08-02 1994-11-15 Merck & Co., Inc. Biologically active compounds isolated from aerobic fermentation of Trichoderma viride
CA2113902A1 (en) * 1991-08-07 1993-02-18 Magda M. Gagliardi Novel cholesterol lowering compound
EP0568946A1 (de) * 1992-05-08 1993-11-10 Takeda Chemical Industries, Ltd. Verbindung TAN-1607A, ihre Derivate, deren Herstellung und Verwendung
US5369125A (en) * 1992-07-17 1994-11-29 Merck & Co., Inc. Cholesterol-lowering agents
US5326783A (en) * 1992-08-25 1994-07-05 Merck & Co., Inc. Cholesterol lowering compounds
US5447717A (en) * 1993-02-25 1995-09-05 Merck & Co., Inc. Cholesterol-lowering agents
GB9306941D0 (en) * 1993-04-02 1993-05-26 Glaxo Group Ltd Chemical compounds
EP0698015A1 (de) 1993-05-14 1996-02-28 Genentech, Inc. Inhibitoren der farnesyl protein-transferase
US5602098A (en) * 1993-05-18 1997-02-11 University Of Pittsburgh Inhibition of farnesyltransferase
US6011175A (en) * 1993-05-18 2000-01-04 University Of Pittsburgh Inhibition of farnesyltransferase
US5705686A (en) * 1993-05-18 1998-01-06 University Of Pittsburgh Inhibition of farnesyl transferase
US5965539A (en) * 1993-05-18 1999-10-12 Univeristy Of Pittsburgh Inhibitors of prenyl transferases
US5834434A (en) * 1993-05-18 1998-11-10 University Of Pittsburgh Inhibitors of farnesyltransferase
US5430055A (en) * 1994-04-08 1995-07-04 Pfizer Inc. Inhibitor of squalene synthase
US6310095B1 (en) 1995-11-06 2001-10-30 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
US6693123B2 (en) 1995-11-06 2004-02-17 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
US6221865B1 (en) 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
US6204293B1 (en) 1995-11-06 2001-03-20 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
US6423519B1 (en) 1998-07-15 2002-07-23 Gpc Biotech Inc. Compositions and methods for inhibiting fungal growth
US6576436B1 (en) * 1998-12-09 2003-06-10 The Arizona Disease Control Research Commission Anticancer agents based on prevention of protein prenylation
FR2933694B1 (fr) * 2008-07-10 2016-10-21 Oreal Utilisation de phenoxyalkylamines dans des compositions cosmetiques et/ou dermatologiques.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837205A (en) * 1986-09-02 1989-06-06 Merck & Co., Inc. Prodrugs of antihypercholesterolemic compounds
IL97535A0 (en) * 1990-03-21 1992-06-21 Merck & Co Inc Squalene synthetase inhibitor dioxabicyclo(1,2,3)octanes,their production and pharmaceutical compositions containing them
US5053425A (en) * 1990-03-21 1991-10-01 Merck & Co., Inc. Novel anti-fungal compounds
US5055487A (en) * 1990-03-21 1991-10-08 Merck & Co., Inc. Novel anti-fungal compounds
NZ239663A (en) * 1990-09-13 1993-07-27 Merck & Co Inc Ester derivatives of dioxabicyclo(3,2,1)-octane, medicaments, and a fungus which makes them
US5026554A (en) * 1990-09-13 1991-06-25 Merck & Co., Inc. Method of inhibiting fungal growth using squalene synthetase inhibitors

Also Published As

Publication number Publication date
YU49292A (sh) 1995-01-31
WO1992020336A2 (en) 1992-11-26
WO1992020336A3 (en) 1993-02-04
CA2109523A1 (en) 1992-11-26
IE921492A1 (en) 1992-11-18
EP0512865A3 (de) 1992-12-02
EP0512865A2 (de) 1992-11-11
AU1908292A (en) 1992-12-30

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