IL101741A - PROCESS FOR PREPARING a-ARYL PYRIDYL CARBINOL DERIVATIVES - Google Patents

PROCESS FOR PREPARING a-ARYL PYRIDYL CARBINOL DERIVATIVES

Info

Publication number
IL101741A
IL101741A IL101741A IL10174192A IL101741A IL 101741 A IL101741 A IL 101741A IL 101741 A IL101741 A IL 101741A IL 10174192 A IL10174192 A IL 10174192A IL 101741 A IL101741 A IL 101741A
Authority
IL
Israel
Prior art keywords
aryl
preparing
compound
pyridyl carbinol
aryl pyridyl
Prior art date
Application number
IL101741A
Other versions
IL101741A0 (en
Original Assignee
Reilly Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reilly Ind Inc filed Critical Reilly Ind Inc
Publication of IL101741A0 publication Critical patent/IL101741A0/en
Publication of IL101741A publication Critical patent/IL101741A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

A process for preparing an a-aryl pyridyl carbinol compound, comprising: initially reacting an a-aryl aldehyde or ketone with a metal or metal ion electron donor; reacting the product of said initial reaction with a 2-or 4-cyanopyridine; and recovering therefrom the a-aryl pyridyl carbinol compound; or, optionally, hydrogenating the a-aryl pyridyl compound in the reacted mixture in the presence of a palladium catalyst, to produce a second reacted mixture including a corresponding a-aryl piperidyl compound.
IL101741A 1991-04-30 1992-04-30 PROCESS FOR PREPARING a-ARYL PYRIDYL CARBINOL DERIVATIVES IL101741A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69368791A 1991-04-30 1991-04-30

Publications (2)

Publication Number Publication Date
IL101741A0 IL101741A0 (en) 1992-12-30
IL101741A true IL101741A (en) 1997-06-10

Family

ID=24785688

Family Applications (1)

Application Number Title Priority Date Filing Date
IL101741A IL101741A (en) 1991-04-30 1992-04-30 PROCESS FOR PREPARING a-ARYL PYRIDYL CARBINOL DERIVATIVES

Country Status (6)

Country Link
EP (1) EP0641322A1 (en)
JP (1) JP3114153B2 (en)
KR (1) KR100214343B1 (en)
AU (1) AU1975592A (en)
IL (1) IL101741A (en)
WO (1) WO1992019596A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100460319B1 (en) * 2001-11-27 2004-12-08 김기원 A system calculating a premium for automobile insurance and managing service for car
CN104003929B (en) * 2014-04-30 2016-07-20 上海应用技术学院 A kind of synthetic method of α, α-diphenyl-4-piperidine carbinols

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235463A3 (en) * 1985-12-20 1990-01-17 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents

Also Published As

Publication number Publication date
JP3114153B2 (en) 2000-12-04
JPH06507400A (en) 1994-08-25
WO1992019596A2 (en) 1992-11-12
KR100214343B1 (en) 1999-08-02
IL101741A0 (en) 1992-12-30
EP0641322A1 (en) 1995-03-08
WO1992019596A3 (en) 1993-04-29
AU1975592A (en) 1992-12-21

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees