IL101655A - The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxiety - Google Patents

The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxiety

Info

Publication number
IL101655A
IL101655A IL10165592A IL10165592A IL101655A IL 101655 A IL101655 A IL 101655A IL 10165592 A IL10165592 A IL 10165592A IL 10165592 A IL10165592 A IL 10165592A IL 101655 A IL101655 A IL 101655A
Authority
IL
Israel
Prior art keywords
rats
veh
amino
test
hydroxy
Prior art date
Application number
IL10165592A
Other languages
English (en)
Hebrew (he)
Other versions
IL101655A0 (en
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL101655A0 publication Critical patent/IL101655A0/xx
Publication of IL101655A publication Critical patent/IL101655A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IL10165592A 1991-04-22 1992-04-20 The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxiety IL101655A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/688,232 US5145866A (en) 1991-04-22 1991-04-22 Method of treating anxiety with the aid of r(+)-3-amino-1-hydroxy-pyrrolidin-2-one

Publications (2)

Publication Number Publication Date
IL101655A0 IL101655A0 (en) 1992-12-30
IL101655A true IL101655A (en) 1998-07-15

Family

ID=24763636

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10165592A IL101655A (en) 1991-04-22 1992-04-20 The use of R) + (- 3-amino-1-hydroxy-pyrrolidin-2-one for the treatment of anxiety

Country Status (9)

Country Link
US (1) US5145866A (fr)
EP (1) EP0510489A1 (fr)
JP (1) JP2580429B2 (fr)
KR (1) KR100210180B1 (fr)
AU (1) AU647707B2 (fr)
CA (1) CA2066468A1 (fr)
HU (1) HU217076B (fr)
IE (1) IE921237A1 (fr)
IL (1) IL101655A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL131713A (en) * 1997-03-11 2004-08-31 Arakis Ltd Dosage forms comprising separate portions of r- and s-enantiomers
US6391922B1 (en) 1998-01-13 2002-05-21 Synchroneuron, Llc Treatment of posttraumatic stress disorder, obsessive-compulsive disorder and related neuropsychiatric disorders
US6982361B1 (en) * 2000-02-25 2006-01-03 The Regents Of The University Of California Method of screening a compound for anxiolytic activity in an Apolipoprotein e knockout animal

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3167476A (en) * 1965-01-26 preparations acting on the central nervous
GB8727792D0 (en) * 1987-11-27 1987-12-31 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
HU9201306D0 (en) 1992-07-28
HUT62789A (en) 1993-06-28
IL101655A0 (en) 1992-12-30
EP0510489A1 (fr) 1992-10-28
JP2580429B2 (ja) 1997-02-12
KR920019349A (ko) 1992-11-19
IE921237A1 (en) 1992-11-04
AU647707B2 (en) 1994-03-24
KR100210180B1 (ko) 1999-07-15
US5145866A (en) 1992-09-08
AU1500092A (en) 1992-10-29
CA2066468A1 (fr) 1992-10-23
HU217076B (hu) 1999-11-29
JPH05112451A (ja) 1993-05-07

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees