IL101293A0 - 4-substituted azetidinones as precursors to 2-substituted-2 carboxy carbapenem antibiotics and a method of producing them - Google Patents

4-substituted azetidinones as precursors to 2-substituted-2 carboxy carbapenem antibiotics and a method of producing them

Info

Publication number
IL101293A0
IL101293A0 IL101293A IL10129392A IL101293A0 IL 101293 A0 IL101293 A0 IL 101293A0 IL 101293 A IL101293 A IL 101293A IL 10129392 A IL10129392 A IL 10129392A IL 101293 A0 IL101293 A0 IL 101293A0
Authority
IL
Israel
Prior art keywords
substituted
producing
precursors
azetidinones
carbapenem antibiotics
Prior art date
Application number
IL101293A
Other languages
English (en)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL101293A0 publication Critical patent/IL101293A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL101293A 1991-03-20 1992-03-19 4-substituted azetidinones as precursors to 2-substituted-2 carboxy carbapenem antibiotics and a method of producing them IL101293A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/672,496 US5189158A (en) 1991-03-20 1991-03-20 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them

Publications (1)

Publication Number Publication Date
IL101293A0 true IL101293A0 (en) 1992-11-15

Family

ID=24698802

Family Applications (1)

Application Number Title Priority Date Filing Date
IL101293A IL101293A0 (en) 1991-03-20 1992-03-19 4-substituted azetidinones as precursors to 2-substituted-2 carboxy carbapenem antibiotics and a method of producing them

Country Status (22)

Country Link
US (1) US5189158A (pl)
EP (1) EP0504612B1 (pl)
JP (1) JPH05125041A (pl)
KR (1) KR920018020A (pl)
CN (2) CN1065061A (pl)
AT (1) ATE162518T1 (pl)
AU (1) AU646934B2 (pl)
CA (1) CA2063326A1 (pl)
CZ (1) CZ284112B6 (pl)
DE (1) DE69224093T2 (pl)
DK (1) DK0504612T3 (pl)
ES (1) ES2113383T3 (pl)
FI (1) FI921179A7 (pl)
GR (1) GR3026388T3 (pl)
HU (2) HU9203677D0 (pl)
IE (1) IE920870A1 (pl)
IL (1) IL101293A0 (pl)
NO (1) NO179869C (pl)
NZ (1) NZ242026A (pl)
PL (4) PL172378B1 (pl)
SG (1) SG47727A1 (pl)
SK (1) SK278789B6 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI96311C (fi) * 1989-12-04 1996-06-10 Squibb Bristol Myers Co Menetelmä farmaseuttisesti käyttökelpoisten 6-(1-hydroksietyyli)-3-(substituoitu tio)-7-okso-1-atsabisyklo/3.2.0/hept-2-eeni-2-karboksyylihappojohdannaisten valmistamiseksi
US5371215A (en) * 1991-03-20 1994-12-06 American Cyanamid Company 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
US5288888A (en) * 1993-04-28 1994-02-22 American Cyanamid Company Process for the synthesis of acetic acid, (dimethoxyphosphinyl) [[1,1-dimethylethyl)dimethylsilyl]-oxy]-, (4-nitrophenyl) methyl ester
US5496816A (en) * 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
EP1392639B1 (en) * 2001-05-03 2008-09-17 Galileo Laboratories, Inc. Pyruvate derivatives
CN116988204B (zh) * 2023-07-13 2025-10-31 博森纺织科技股份有限公司 一种防臭抑菌面料及其生产工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055573A (en) * 1976-11-19 1991-10-08 Merck & Co., Inc. Process for preparing 1-carba-2-penem-3-carboxylic acid
US4174316A (en) * 1978-08-14 1979-11-13 Merck & Co., Inc. 4-Iodomethylazetidin-2-one
US4350631A (en) * 1980-12-18 1982-09-21 Merck & Co., Inc. 6- and 4-Substituted-1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylates
EP0089139A2 (en) * 1982-03-16 1983-09-21 Beecham Group Plc Antibiotics, their preparation and use
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
GB8804058D0 (en) * 1988-02-22 1988-03-23 Fujisawa Pharmaceutical Co 3-alkenyl-1-azabicyclo(3 2 0)hept-2-ene-2-carboxylic acid compounds
JPH03120280A (ja) * 1989-10-03 1991-05-22 Shionogi & Co Ltd ハロメチルカルバペネム化合物の製法
US5068232A (en) * 1990-04-10 1991-11-26 American Cyanamid Company Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
US5051502A (en) * 1990-06-06 1991-09-24 University Of Notre Dame Du Lac Rhodium catalyzed cyclization process for bicyclic β-lactams

Also Published As

Publication number Publication date
HUT61522A (en) 1993-01-28
SG47727A1 (en) 1998-04-17
NO921097L (no) 1992-09-21
CZ284112B6 (cs) 1998-08-12
NO179869C (no) 1997-01-02
DE69224093D1 (de) 1998-02-26
KR920018020A (ko) 1992-10-21
NZ242026A (en) 1994-10-26
PL172298B1 (pl) 1997-09-30
FI921179A0 (fi) 1992-03-19
IE920870A1 (en) 1992-09-23
NO179869B (no) 1996-09-23
EP0504612B1 (en) 1998-01-21
PL172378B1 (pl) 1997-09-30
FI921179L (fi) 1992-09-21
EP0504612A2 (en) 1992-09-23
JPH05125041A (ja) 1993-05-21
NO921097D0 (no) 1992-03-19
CS83392A3 (en) 1992-10-14
CA2063326A1 (en) 1992-09-21
AU646934B2 (en) 1994-03-10
CN1166489A (zh) 1997-12-03
CN1065061A (zh) 1992-10-07
HU9203677D0 (en) 1993-03-29
PL171733B1 (pl) 1997-06-30
FI921179A7 (fi) 1992-09-21
AU1301392A (en) 1992-09-24
EP0504612A3 (en) 1993-01-27
DE69224093T2 (de) 1998-05-07
PL171202B1 (pl) 1997-03-28
US5189158A (en) 1993-02-23
ES2113383T3 (es) 1998-05-01
HU9200917D0 (en) 1992-05-28
GR3026388T3 (en) 1998-06-30
SK278789B6 (sk) 1998-02-04
DK0504612T3 (da) 1998-09-21
ATE162518T1 (de) 1998-02-15
PL293902A1 (en) 1993-10-18

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Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees