IE894077L - Transdermal therapeutical system comprising¹norpseudoephedrine as active component - Google Patents
Transdermal therapeutical system comprising¹norpseudoephedrine as active componentInfo
- Publication number
- IE894077L IE894077L IE894077A IE407789A IE894077L IE 894077 L IE894077 L IE 894077L IE 894077 A IE894077 A IE 894077A IE 407789 A IE407789 A IE 407789A IE 894077 L IE894077 L IE 894077L
- Authority
- IE
- Ireland
- Prior art keywords
- therapeutical system
- transdermal therapeutical
- polymeric material
- transdermal
- material comprises
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a transdermal therapeutic system for applying an active substance to the skin and consisting of a backing layer impermeable to the active substance, a reservoir layer and, if appropriate, a detachable protective layer, the reservoir layer being adhesive and containing 10-90% by weight of polymer material, 0-30% by weight of softener and 0.1-20% by weight of a norpseudoephedrine.
Claims (15)
1. A transdermal therapeutical system for the administration of an antiadipogenic to the skin comprising a backing layer which is 10 impermeable to the active substance, a reservoir layer, and optionally a removable protective layer, characterized in that the reservoir layer is pressure-sensitive adhesive and comprises 10-90% by weight polymeric material, 0-30% by weight softener and, as active substance, 0.1-20% by weight norpseudoephedrine, the active substance being present in 15 homogeneous mixture with the components of the pressure-sensitive adhesive reservoir layer.
2. The transdermal therapeutical system according to claim 1, characterized in that the polymeric material is selected from the group 20 consisting of block copolymers on the basis of styrene and 1,3-dienes, polyisobutylenes, polymers on the basis of acrylate and/or methacrylate, and esters of hydrogenated colophonium.
3. The transdermal therapeutical system according to claim 2, 25 characterized in that the polymeric material comprises linear styrene-isoprene block copolymer.
4. The transdermal therapeutical system according to claim 2, characterized in that the polymeric material comprises linear 30 styrene-butadiene block copolymer.
5. The transdermal therapeutical system according to claim 2, characterized in that the polymeric material comprises self-crosslinking acrylate copolymer of 2-ethylhexyl acrylate, vinyl 35 acetate, acrylic acid, and titanium chelate ester.
6. The transdermal therapeutical system according to claim 2, characterized in that the polymeric material comprises non-self-crosslinking acrylate copolymers of 2-ethylhexyl acrylate, vinyl acetate, and acrylic acid.
7. The transdermal therapeutical system according to claim 2, characterized in that the polymeric material comprises as polymer on the basis of methacrvlates a copolymer of di-methylaminoethyl methacrylate and neutral methacrylic acid esters.
8. The transdermal therapeutical system according to claim 2, characterized in that the polymeric material comprises as ester of the hydrogenated colophonium the methylesters thereof.
9. The transdermal therapeutical system according to claim 2, characterized in that the polymeric material comprises as ester of the hydrogenated colophonium the glyceryl esters thereof.
10. The transdermal therapeutical system according to claim 1, characterized in that the softeners are selected from the group consisting of vicinal alcohols and esters.
11. The transdermal therapeutical system according to claim 10, characterized in that it comprises propanediol-1, 2 as softener.
12. The transdermal therapeutical system according to claim 10, characterized in that it comprises di-n-butyl adipate as softener.
13. The transdermal therapeutical system according to claim 10, characterized in that it comprises triglycerides as softener. 10
14. The transdermal therapeutical system according to claim 10, characterized in that it comprises glycerol as softener.
15. A transdermal therapeutical system according to claim 1 substantially as hereinbefore described. TOMKINS & CO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3843237A DE3843237A1 (en) | 1988-12-22 | 1988-12-22 | TRANSDERMAL THERAPEUTIC SYSTEM WITH AN ANTIADIPOSITUM AS AN ACTIVE INGREDIENT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE894077L true IE894077L (en) | 1990-06-22 |
| IE63878B1 IE63878B1 (en) | 1995-06-14 |
Family
ID=6369853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE407789A IE63878B1 (en) | 1988-12-22 | 1989-12-19 | Transdermal therapeutical system comprising norpseudoephedrine as active component |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0374725B1 (en) |
| JP (1) | JP2602108B2 (en) |
| KR (1) | KR950015055B1 (en) |
| AT (1) | ATE93147T1 (en) |
| AU (1) | AU614208B2 (en) |
| CA (1) | CA2006425C (en) |
| CS (1) | CS275356B2 (en) |
| DD (1) | DD290581A5 (en) |
| DE (2) | DE3843237A1 (en) |
| DK (1) | DK651089A (en) |
| ES (1) | ES2045369T3 (en) |
| FI (1) | FI95772C (en) |
| HU (1) | HU203280B (en) |
| IE (1) | IE63878B1 (en) |
| IL (1) | IL92678A (en) |
| MY (1) | MY105074A (en) |
| NO (1) | NO178784C (en) |
| NZ (1) | NZ231909A (en) |
| PH (1) | PH25854A (en) |
| PL (1) | PL163292B1 (en) |
| PT (1) | PT92650B (en) |
| YU (1) | YU47075B (en) |
| ZA (1) | ZA899879B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3939376C1 (en) * | 1989-11-29 | 1991-05-08 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De | |
| DE4342893C2 (en) * | 1993-12-16 | 1999-09-23 | Lohmann Gmbh & Co Kg | Reversible adhesive, residue-free removable pressure sensitive adhesive, process for its production and use as re-adhesive pressure sensitive adhesive articles |
| AU2727801A (en) * | 1999-12-16 | 2001-06-25 | Dermatrends, Inc. | Transdermal administration of phenylpropanolamine |
| US6602912B2 (en) | 2000-06-30 | 2003-08-05 | Dermatrends, Inc. | Transdermal administration of phenylpropanolamine |
| US6673363B2 (en) | 1999-12-16 | 2004-01-06 | Dermatrends, Inc. | Transdermal and topical administration of local anesthetic agents using basic enhancers |
| US6719997B2 (en) | 2000-06-30 | 2004-04-13 | Dermatrends, Inc. | Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers |
| KR100956865B1 (en) * | 2009-08-10 | 2010-05-11 | 주식회사 라이트론 | Slide pressure packing type linear lighting apparatus |
| US20190298661A1 (en) * | 2016-10-31 | 2019-10-03 | The Corporation Of Mercer University | Transdermal Delivery of Phenethylamine Monoamine Releasers |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
| JPS57116011A (en) * | 1981-01-08 | 1982-07-19 | Nitto Electric Ind Co Ltd | Pharmaceutical preparation |
| JPS60185713A (en) * | 1984-03-05 | 1985-09-21 | Nitto Electric Ind Co Ltd | Percutaneous preparation and its production |
| EP0156080B2 (en) * | 1984-03-05 | 1993-10-20 | Nitto Denko Corporation | Percutaneous absorption type adhesive pharmaceutical preparation |
| US4692462A (en) * | 1985-03-18 | 1987-09-08 | Menley & James Laboratories, Ltd. | Compositions and method of controlling transdermal penetration of topical and systemic agents |
| DE3629304A1 (en) * | 1986-08-28 | 1988-03-24 | Lohmann Gmbh & Co Kg | TRANSDERMAL THERAPEUTIC SYSTEM, ITS USE AND METHOD FOR THE PRODUCTION THEREOF |
| DE3743945A1 (en) * | 1987-09-01 | 1989-03-09 | Lohmann Gmbh & Co Kg | DEVICE FOR DELIVERING SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE |
-
1988
- 1988-12-22 DE DE3843237A patent/DE3843237A1/en active Granted
-
1989
- 1989-12-13 IL IL9267889A patent/IL92678A/en not_active IP Right Cessation
- 1989-12-14 MY MYPI89001760A patent/MY105074A/en unknown
- 1989-12-14 AT AT89123091T patent/ATE93147T1/en not_active IP Right Cessation
- 1989-12-14 DE DE8989123091T patent/DE58905320D1/en not_active Expired - Fee Related
- 1989-12-14 ES ES89123091T patent/ES2045369T3/en not_active Expired - Lifetime
- 1989-12-14 EP EP89123091A patent/EP0374725B1/en not_active Expired - Lifetime
- 1989-12-18 AU AU46843/89A patent/AU614208B2/en not_active Ceased
- 1989-12-19 FI FI896097A patent/FI95772C/en not_active IP Right Cessation
- 1989-12-19 IE IE407789A patent/IE63878B1/en not_active IP Right Cessation
- 1989-12-19 CS CS897193A patent/CS275356B2/en unknown
- 1989-12-19 YU YU240589A patent/YU47075B/en unknown
- 1989-12-20 NZ NZ231909A patent/NZ231909A/en unknown
- 1989-12-20 DK DK651089A patent/DK651089A/en not_active Application Discontinuation
- 1989-12-20 PH PH39752A patent/PH25854A/en unknown
- 1989-12-21 CA CA002006425A patent/CA2006425C/en not_active Expired - Fee Related
- 1989-12-21 HU HU896721A patent/HU203280B/en not_active IP Right Cessation
- 1989-12-21 DD DD89336084A patent/DD290581A5/en not_active IP Right Cessation
- 1989-12-21 ZA ZA899879A patent/ZA899879B/en unknown
- 1989-12-21 PT PT92650A patent/PT92650B/en not_active IP Right Cessation
- 1989-12-21 NO NO895173A patent/NO178784C/en unknown
- 1989-12-22 KR KR1019890019229A patent/KR950015055B1/en not_active IP Right Cessation
- 1989-12-22 JP JP1331442A patent/JP2602108B2/en not_active Expired - Lifetime
- 1989-12-22 PL PL89282948A patent/PL163292B1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |