IE891372L - A monoclonal antibody for the selective immunological¹determination of intact procollagen peptide (type iii) and¹procollagen (type iii) in body fluids - Google Patents

A monoclonal antibody for the selective immunological¹determination of intact procollagen peptide (type iii) and¹procollagen (type iii) in body fluids

Info

Publication number
IE891372L
IE891372L IE891372A IE137289A IE891372L IE 891372 L IE891372 L IE 891372L IE 891372 A IE891372 A IE 891372A IE 137289 A IE137289 A IE 137289A IE 891372 L IE891372 L IE 891372L
Authority
IE
Ireland
Prior art keywords
type iii
monoclonal antibody
selective
body fluids
procollagen peptide
Prior art date
Application number
IE891372A
Other versions
IE66320B1 (en
Inventor
Dietrich Brocks
Volkmar Guenzlerpukall
Henning Hachmann
Juergen Puenter
Rupert Timpl
Original Assignee
Timothy Gerard Vaughan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Timothy Gerard Vaughan filed Critical Timothy Gerard Vaughan
Publication of IE891372L publication Critical patent/IE891372L/en
Publication of IE66320B1 publication Critical patent/IE66320B1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The said peptide can be determined with great accuracy with the aid of a monoclonal antibody which is directed specifically against one epitope of amino-terminal procollagen peptide (type III) which is not present on the fragment Col 1 and of a second monoclonal or polyclonal antibody against an epitope of amino-terminal procollagen peptide (type III).
IE137289A 1988-04-27 1989-04-26 A monoclonal antibody for the selective immunological determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids IE66320B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3814216 1988-04-27

Publications (2)

Publication Number Publication Date
IE891372L true IE891372L (en) 1989-10-27
IE66320B1 IE66320B1 (en) 1995-12-27

Family

ID=6353005

Family Applications (1)

Application Number Title Priority Date Filing Date
IE137289A IE66320B1 (en) 1988-04-27 1989-04-26 A monoclonal antibody for the selective immunological determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids

Country Status (12)

Country Link
EP (1) EP0339443B1 (en)
JP (1) JPH07110880B2 (en)
AT (1) ATE115963T1 (en)
CA (1) CA1338324C (en)
DE (1) DE58908787D1 (en)
DK (1) DK169571B1 (en)
ES (1) ES2065350T3 (en)
FI (1) FI98705C (en)
GR (1) GR3014957T3 (en)
IE (1) IE66320B1 (en)
NO (1) NO179107C (en)
PT (1) PT90369B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010862A (en) * 1987-11-06 2000-01-04 Washington Research Foundation Methods of detecting collagen type III degradation in vivo
DE4225038C2 (en) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Production and use of antibodies against collagen
DE59406512D1 (en) * 1993-07-28 1998-08-27 Boehringer Mannheim Gmbh IMMUNOASSAY TO DETECT COLLAGEN TYPE I OR COLLAGEN FRAGMENTS THEREOF
WO1996012193A1 (en) 1994-10-17 1996-04-25 Osteometer Bio Tech A/S Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
JP3913787B2 (en) 1996-12-09 2007-05-09 オステオメーター・ビオテク・エー／エス Method for sandwich measurement of type I collagen fragments
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
AU4362399A (en) * 1998-05-28 1999-12-13 Bayer Aktiengesellschaft Monoclonal antibody and assay for detecting piiinp
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209149A1 (en) * 1982-03-13 1983-10-06 Hoechst Ag METHOD FOR THE COMMON IMMUNOLOGICAL DETERMINATION OF PROCOLLAGEN PEPTIDE (TYPE III) AND PROCOLLAGEN PEPTIDE COL 1 (TYPE III) AND METHOD FOR THE PRODUCTION OF ANTI-PROCOLLAGEN PEPTIDE COL 1 (TYPE III) SERUM

Also Published As

Publication number Publication date
FI891953A (en) 1989-10-28
IE66320B1 (en) 1995-12-27
PT90369A (en) 1989-11-10
GR3014957T3 (en) 1995-05-31
DK202189D0 (en) 1989-04-26
CA1338324C (en) 1996-05-14
NO891732L (en) 1989-10-30
JPH07110880B2 (en) 1995-11-29
JPH0213396A (en) 1990-01-17
NO179107B (en) 1996-04-29
ATE115963T1 (en) 1995-01-15
FI98705B (en) 1997-04-30
NO891732D0 (en) 1989-04-26
NO179107C (en) 1996-08-07
ES2065350T3 (en) 1995-02-16
DK202189A (en) 1989-10-28
DE58908787D1 (en) 1995-02-02
FI98705C (en) 1997-08-11
EP0339443B1 (en) 1994-12-21
DK169571B1 (en) 1994-12-05
EP0339443A3 (en) 1990-05-09
FI891953A0 (en) 1989-04-25
EP0339443A2 (en) 1989-11-02
PT90369B (en) 1994-08-31

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Legal Events

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