IE890126L - Stabilization of cephalosporin derivatives - Google Patents
Stabilization of cephalosporin derivativesInfo
- Publication number
- IE890126L IE890126L IE890126A IE12689A IE890126L IE 890126 L IE890126 L IE 890126L IE 890126 A IE890126 A IE 890126A IE 12689 A IE12689 A IE 12689A IE 890126 L IE890126 L IE 890126L
- Authority
- IE
- Ireland
- Prior art keywords
- cephalosporin derivatives
- stabilization
- cephalosporin
- derivatives
- stabilisation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cephalosporin Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A stable composition of cephalosporin derivatives obtainable by drying from a joint solution of a cephalosporin derivative as active ingredient and lactose, glucose, sucrose or galactose as stabiliser, and a process for the stabilisation of cephalosporin derivatives are described.
[EP0325112A1]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3801179A DE3801179A1 (en) | 1988-01-18 | 1988-01-18 | STABILIZATION OF CEPHALOSPORINE DERIVATIVES BY DRYING WITH A STABILIZER AND STABLE PREPARATION FORMS WITH CEPHALOSPORINE DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
IE890126L true IE890126L (en) | 1989-07-18 |
Family
ID=6345430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE890126A IE890126L (en) | 1988-01-18 | 1989-01-17 | Stabilization of cephalosporin derivatives |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0325112A1 (en) |
JP (1) | JPH01216996A (en) |
KR (1) | KR890011894A (en) |
CN (1) | CN1034670A (en) |
AU (1) | AU2853989A (en) |
DE (1) | DE3801179A1 (en) |
DK (1) | DK19489A (en) |
HU (1) | HUT49487A (en) |
IE (1) | IE890126L (en) |
IL (1) | IL88957A0 (en) |
PT (1) | PT89464A (en) |
ZA (1) | ZA89332B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19539574A1 (en) | 1995-10-25 | 1997-04-30 | Boehringer Mannheim Gmbh | Preparations and processes for stabilizing biological materials by means of drying processes without freezing |
EP0913177A1 (en) * | 1997-11-03 | 1999-05-06 | Roche Diagnostics GmbH | Process for producing dry, amorphous products comprising biological active materials by means of convection drying technique, especially spray drying |
EP0913178A1 (en) * | 1997-11-03 | 1999-05-06 | Boehringer Mannheim Gmbh | Process for the manufacture of dry, amorphous products comprising biologically active material by means of convection drying and products obtainable by the process |
EP1656930A1 (en) * | 2004-11-10 | 2006-05-17 | Basilea Pharmaceutica AG | Stabilized freeze-dried formulation for cephalosporin derivatives |
CN101590061B (en) * | 2009-04-14 | 2010-09-29 | 深圳立健药业有限公司 | Medicinal composition of cefotetan disodium |
ME02854B (en) | 2013-03-13 | 2018-04-20 | Theravance Biopharma Antibiotics Ip Llc | Hydrochloride salts of an antibiotic compound |
KR101935186B1 (en) * | 2014-09-04 | 2019-01-03 | 시오노기세야쿠 가부시키가이샤 | Pharmaceutical preparation comprising cephalosporin having catechol groups |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2017373A1 (en) * | 1969-04-15 | 1971-04-22 | Orsymonde S A , Paris | Lyophilized products and processes for their manufacture |
JPS5132723A (en) * | 1974-09-11 | 1976-03-19 | Toyama Chemical Co Ltd | YOJOKAIGATACHUSHAYOSEIZAI NO SHINKISEIHO NARABINI SONOYOKAI YOSUI YOEKI |
JPS5711909A (en) * | 1980-06-23 | 1982-01-21 | Shionogi & Co Ltd | Stable freeze-dried preparation of beta-lactam |
JPS6045514A (en) * | 1983-08-22 | 1985-03-12 | Shionogi & Co Ltd | Stable antibacterial lyophilized pharmactical preparation |
DE3577656D1 (en) * | 1984-07-23 | 1990-06-21 | Lilly Co Eli | PHARMACEUTICAL COMPOSITIONS OF CEFTAZIDIM. |
JP2690009B2 (en) * | 1986-07-10 | 1997-12-10 | エーザイ 株式会社 | Cefalosporin injection |
-
1988
- 1988-01-18 DE DE3801179A patent/DE3801179A1/en not_active Withdrawn
-
1989
- 1989-01-05 EP EP89100117A patent/EP0325112A1/en not_active Withdrawn
- 1989-01-15 IL IL88957A patent/IL88957A0/en unknown
- 1989-01-16 ZA ZA89332A patent/ZA89332B/en unknown
- 1989-01-16 CN CN89100245A patent/CN1034670A/en active Pending
- 1989-01-16 KR KR1019890000404A patent/KR890011894A/en not_active Application Discontinuation
- 1989-01-17 DK DK019489A patent/DK19489A/en not_active Application Discontinuation
- 1989-01-17 AU AU28539/89A patent/AU2853989A/en not_active Abandoned
- 1989-01-17 HU HU89169A patent/HUT49487A/en unknown
- 1989-01-17 IE IE890126A patent/IE890126L/en unknown
- 1989-01-17 PT PT89464A patent/PT89464A/en not_active Application Discontinuation
- 1989-01-18 JP JP1009617A patent/JPH01216996A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DK19489D0 (en) | 1989-01-17 |
DK19489A (en) | 1989-07-19 |
AU2853989A (en) | 1989-07-20 |
DE3801179A1 (en) | 1989-07-27 |
PT89464A (en) | 1990-02-08 |
HUT49487A (en) | 1989-10-30 |
EP0325112A1 (en) | 1989-07-26 |
KR890011894A (en) | 1989-08-23 |
ZA89332B (en) | 1989-09-27 |
CN1034670A (en) | 1989-08-16 |
IL88957A0 (en) | 1989-08-15 |
JPH01216996A (en) | 1989-08-30 |
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