IE872986L - Process for preparing prednisolone 17-ethyl-carbonate by¹rearrangement of prednisolene 21-ethylcarbonate - Google Patents

Process for preparing prednisolone 17-ethyl-carbonate by¹rearrangement of prednisolene 21-ethylcarbonate

Info

Publication number
IE872986L
IE872986L IE872986A IE298687A IE872986L IE 872986 L IE872986 L IE 872986L IE 872986 A IE872986 A IE 872986A IE 298687 A IE298687 A IE 298687A IE 872986 L IE872986 L IE 872986L
Authority
IE
Ireland
Prior art keywords
carbonate
prednisolene
ethylcarbonate
ethyl
prednisolone
Prior art date
Application number
IE872986A
Original Assignee
Gcm 600 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gcm 600 Ltd filed Critical Gcm 600 Ltd
Publication of IE872986L publication Critical patent/IE872986L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

(C1-C4)alkyl prednisolone- or methylprednisolone-21-carbonate <IMAGE> is rearranged using lithium di-(C1-C4)alkylcuprate.e [EP0266719A1]
IE872986A 1986-11-06 1987-11-05 Process for preparing prednisolone 17-ethyl-carbonate by¹rearrangement of prednisolene 21-ethylcarbonate IE872986L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863637806 DE3637806A1 (en) 1986-11-06 1986-11-06 METHOD FOR PRODUCING PREDNISOLON-17-ETHYLCARBONATE BY TRANSFERRING PREDNISOLON-21-ETHYLCARBONATE

Publications (1)

Publication Number Publication Date
IE872986L true IE872986L (en) 1988-05-06

Family

ID=6313295

Family Applications (1)

Application Number Title Priority Date Filing Date
IE872986A IE872986L (en) 1986-11-06 1987-11-05 Process for preparing prednisolone 17-ethyl-carbonate by¹rearrangement of prednisolene 21-ethylcarbonate

Country Status (9)

Country Link
EP (1) EP0266719A1 (en)
JP (1) JPS63132897A (en)
AU (1) AU8080687A (en)
DE (1) DE3637806A1 (en)
DK (1) DK581887A (en)
HU (1) HUT45545A (en)
IE (1) IE872986L (en)
PT (1) PT86086B (en)
ZA (1) ZA878305B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids
DE2735110A1 (en) * 1977-08-04 1979-02-15 Hoechst Ag CORTICOID-17-ALKYLCARBONATE AND METHOD FOR THE PRODUCTION THEREOF
DE3133082A1 (en) * 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen NEW HYDROCORTISON DERIVATIVES, THEIR PRODUCTION AND USE

Also Published As

Publication number Publication date
PT86086A (en) 1987-12-01
DK581887A (en) 1988-05-07
ZA878305B (en) 1988-05-02
DK581887D0 (en) 1987-11-05
JPS63132897A (en) 1988-06-04
AU8080687A (en) 1988-05-12
EP0266719A1 (en) 1988-05-11
PT86086B (en) 1990-11-20
HUT45545A (en) 1988-07-28
DE3637806A1 (en) 1988-05-19

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