AU8080687A - Process for preparing prednisolone 17-ethylcarbonate by rearrangement of prednisolone 21-ethylcarbonate - Google Patents
Process for preparing prednisolone 17-ethylcarbonate by rearrangement of prednisolone 21-ethylcarbonateInfo
- Publication number
- AU8080687A AU8080687A AU80806/87A AU8080687A AU8080687A AU 8080687 A AU8080687 A AU 8080687A AU 80806/87 A AU80806/87 A AU 80806/87A AU 8080687 A AU8080687 A AU 8080687A AU 8080687 A AU8080687 A AU 8080687A
- Authority
- AU
- Australia
- Prior art keywords
- ethylcarbonate
- prednisolone
- rearrangement
- preparing
- preparing prednisolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- CWVNDXWCEADDCU-ZJUZSDNKSA-N ethyl [(8s,9s,10r,11s,13s,14s,17r)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl] carbonate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)CO)(OC(=O)OCC)[C@@]1(C)C[C@@H]2O CWVNDXWCEADDCU-ZJUZSDNKSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 title 1
- 229960005205 prednisolone Drugs 0.000 title 1
- 230000008707 rearrangement Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3637806 | 1986-11-06 | ||
| DE19863637806 DE3637806A1 (en) | 1986-11-06 | 1986-11-06 | METHOD FOR PRODUCING PREDNISOLON-17-ETHYLCARBONATE BY TRANSFERRING PREDNISOLON-21-ETHYLCARBONATE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU8080687A true AU8080687A (en) | 1988-05-12 |
Family
ID=6313295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU80806/87A Abandoned AU8080687A (en) | 1986-11-06 | 1987-11-05 | Process for preparing prednisolone 17-ethylcarbonate by rearrangement of prednisolone 21-ethylcarbonate |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0266719A1 (en) |
| JP (1) | JPS63132897A (en) |
| AU (1) | AU8080687A (en) |
| DE (1) | DE3637806A1 (en) |
| DK (1) | DK581887A (en) |
| HU (1) | HUT45545A (en) |
| IE (1) | IE872986L (en) |
| PT (1) | PT86086B (en) |
| ZA (1) | ZA878305B (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1440063A (en) * | 1972-08-11 | 1976-06-23 | Glaxo Lab Ltd | 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids |
| DE2735110A1 (en) * | 1977-08-04 | 1979-02-15 | Hoechst Ag | CORTICOID-17-ALKYLCARBONATE AND METHOD FOR THE PRODUCTION THEREOF |
| DE3133082A1 (en) * | 1981-08-18 | 1983-03-10 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | NEW HYDROCORTISON DERIVATIVES, THEIR PRODUCTION AND USE |
-
1986
- 1986-11-06 DE DE19863637806 patent/DE3637806A1/en not_active Withdrawn
-
1987
- 1987-11-02 EP EP87116074A patent/EP0266719A1/en not_active Withdrawn
- 1987-11-04 HU HU874943A patent/HUT45545A/en unknown
- 1987-11-05 IE IE872986A patent/IE872986L/en unknown
- 1987-11-05 ZA ZA878305A patent/ZA878305B/en unknown
- 1987-11-05 DK DK581887A patent/DK581887A/en not_active Application Discontinuation
- 1987-11-05 JP JP62278453A patent/JPS63132897A/en active Pending
- 1987-11-05 AU AU80806/87A patent/AU8080687A/en not_active Abandoned
- 1987-11-05 PT PT86086A patent/PT86086B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3637806A1 (en) | 1988-05-19 |
| DK581887A (en) | 1988-05-07 |
| PT86086B (en) | 1990-11-20 |
| JPS63132897A (en) | 1988-06-04 |
| HUT45545A (en) | 1988-07-28 |
| ZA878305B (en) | 1988-05-02 |
| PT86086A (en) | 1987-12-01 |
| IE872986L (en) | 1988-05-06 |
| EP0266719A1 (en) | 1988-05-11 |
| DK581887D0 (en) | 1987-11-05 |
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