IE852588L - Process for preparing mucopolysaccharides - Google Patents

Process for preparing mucopolysaccharides

Info

Publication number
IE852588L
IE852588L IE852588A IE258885A IE852588L IE 852588 L IE852588 L IE 852588L IE 852588 A IE852588 A IE 852588A IE 258885 A IE258885 A IE 258885A IE 852588 L IE852588 L IE 852588L
Authority
IE
Ireland
Prior art keywords
compositions
chains
usp
mucopolysaccharides
preparing
Prior art date
Application number
IE852588A
Other versions
IE58619B1 (en
Original Assignee
Choay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8415978A external-priority patent/FR2572080B1/en
Application filed by Choay Sa filed Critical Choay Sa
Publication of IE852588L publication Critical patent/IE852588L/en
Publication of IE58619B1 publication Critical patent/IE58619B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Process for preparing mucopolysaccharides or MPS possessing high antithrombotic activity, characterized by the fact that compositions formed form a majority of MPS chains having a molecular weight of about 1800 to 8000 daltons, a YW titer and a ratio of the YW/USP titers higher than those of heparin to at least one fractionation step, in order to selectively separate from said compositions at least the major part of chains having MW lower than about 2000 and those having a higher MW but a sulfate content lower than the sulfate average contents of the mixture chain and that the fractions devoid from said chains are recovered, said fractions having a lower ratio of YW/USP titers than the starting compositions but higher than the one of heparin with USP titer higher than the one of the starting compositions.
IE258885A 1984-10-18 1985-10-18 A process for preparing mucopolysaccharidic compositions having a high antithrombotic activity IE58619B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8415979 1984-10-18
FR8415978A FR2572080B1 (en) 1984-10-18 1984-10-18 PROCESS FOR THE PREPARATION OF MUCOPOLYSACCHARIDE COMPOSITIONS WITH HIGH ANTITHROMBOTIC ACTIVITY, THE COMPOSITIONS OBTAINED AND THEIR APPLICATION AS MEDICAMENTS

Publications (2)

Publication Number Publication Date
IE852588L true IE852588L (en) 1986-04-18
IE58619B1 IE58619B1 (en) 1993-10-20

Family

ID=26224209

Family Applications (1)

Application Number Title Priority Date Filing Date
IE258885A IE58619B1 (en) 1984-10-18 1985-10-18 A process for preparing mucopolysaccharidic compositions having a high antithrombotic activity

Country Status (11)

Country Link
EP (1) EP0181252B1 (en)
AT (1) ATE47402T1 (en)
AU (1) AU578750B2 (en)
CA (1) CA1260461A (en)
DE (1) DE3573786D1 (en)
DK (1) DK172887B1 (en)
ES (1) ES8604993A1 (en)
GR (1) GR852518B (en)
IE (1) IE58619B1 (en)
PT (1) PT81343B (en)
SG (1) SG78689G (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2755372B1 (en) 1996-11-07 1998-12-24 Elf Aquitaine IONOPHORESIS DEVICE COMPRISING AT LEAST ONE MEMBRANE ELECTRODE ASSEMBLY FOR THE TRANSCUTANEOUS ADMINISTRATION OF ACTIVE PRINCIPLES TO A SUBJECT

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478646A2 (en) * 1980-03-20 1981-09-25 Choay Sa MUCOPOLYSACCHARIDIC COMPOSITION HAVING A COAGULATION REGULATING ACTIVITY, MEDICAMENT CONTAINING THE SAME, AND METHOD FOR OBTAINING THE SAME
US4500519A (en) * 1978-11-06 1985-02-19 Choay S.A. Mucopolysaccharides having biological properties, preparation and method of use
FR2440376A1 (en) * 1978-11-06 1980-05-30 Choay Sa MUCOPOLYSACCHARIDIC COMPOSITION HAVING REGULATORY COAGULATION ACTIVITY, MEDICAMENT CONTAINING SAME AND METHOD FOR OBTAINING SAME
SE449753B (en) * 1978-11-06 1987-05-18 Choay Sa MUCOPOLYSACCARIDE COMPOSITION WITH REGULATORY EFFECTS ON COAGULATION, MEDICINAL CONTAINING ITS SAME AND PROCEDURE FOR PREPARING THEREOF
FR2495935A1 (en) * 1980-12-15 1982-06-18 Choay Sa Muco:polysaccharide fractions derived from heparin - with selective inhibitory action against factor Xa but low anticoagulant activity
FR2503714B1 (en) * 1981-04-10 1986-11-21 Choay Sa PROCESS FOR OBTAINING BIOLOGICALLY ACTIVE MUCOPOLYSACCHARIDES, OF HIGH PURITY, BY DEPOLYMERIZATION OF HEPARIN
US4533549A (en) * 1983-01-04 1985-08-06 Lasker Sigmund E Antithrombotic agent

Also Published As

Publication number Publication date
DK475285D0 (en) 1985-10-17
SG78689G (en) 1990-07-13
EP0181252A1 (en) 1986-05-14
CA1260461A (en) 1989-09-26
GR852518B (en) 1986-02-05
DK172887B1 (en) 1999-09-06
PT81343B (en) 1987-11-11
ES8604993A1 (en) 1986-03-16
AU4886085A (en) 1986-04-24
ATE47402T1 (en) 1989-11-15
IE58619B1 (en) 1993-10-20
AU578750B2 (en) 1988-11-03
EP0181252B1 (en) 1989-10-18
PT81343A (en) 1985-11-01
DE3573786D1 (en) 1989-11-23
ES547916A0 (en) 1986-03-16
DK475285A (en) 1986-04-19

Similar Documents

Publication Publication Date Title
ZA871335B (en) New aryl-substituted(n-piperidinyl)methyl-and(n-piperazinyl)-methylazoles having antipsychotic properties
EP0158976A3 (en) Molecular sieve compositions
AU7467187A (en) Injectable implant composition having improved intrudability
DE3887247T2 (en) Solid, indigestible fat-like compounds.
EP0263703A3 (en) Lactone modified, esterified or aminated additives useful in oleaginous compositions
KR960008820B1 (en) Polymer blend compositions
GB8606903D0 (en) Bituminous composition
EP0336716A3 (en) Lactone modified viscosity modifiers useful in oleaginous compositions
FR2653442B1 (en)
ATE125191T1 (en) METHOD FOR PRODUCING LIGNOCELLULOSIC MATERIAL PRODUCTS.
AR242599A1 (en) Method, composition and product produced by delayed gelation in the polymerization of cycloolefins
AU6247386A (en) N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents
IL72820A0 (en) Injectable physiologically-acceptable polymeric compositions
ES8701434A1 (en) Cableway of wire mesh.
DE3573786D1 (en) Process for preparing compositions of mucopolysaccharides having a high antithrombotic activity
ZA89267B (en) Bituminous compositions
PT84837A (en) Wood preservative compositions and a process for their production
ES8706878A1 (en) Thermoplastic mass passed between rollers
EP0249727A3 (en) Water-dilutable filler composition
EP0319915A3 (en) Method for producing 4,4'-dibromobiphenyl
DE3474561D1 (en) Moulding compositions based on high molecular weight polyalkylene terephthalates
EP0284510A3 (en) N-[N alpha-(1(S)-carboxy-3-cyclohexyl-propyl)-1-lysyl] N-cyclopentylglycine as antihypertensives
Cozewith et al. End-Capped Polymer Chains, Graft and Star Copolymers, and Process of Making Same
ATE105465T1 (en) COMPOSITION OF A DIET FOOD IN THE FORM OF COOKIES WITH HIGH CONTENT OF DIETARY FIBER AND LOW CONTENT OF CALORIES AND PROCESS FOR THEIR PRODUCTION.
GB8822613D0 (en) Process for producing bitumen-polymer compositions

Legal Events

Date Code Title Description
MK9A Patent expired