IE843059L - 4-(2-phenoxyethyl)-1,2,4-triazolones - Google Patents

4-(2-phenoxyethyl)-1,2,4-triazolones

Info

Publication number
IE843059L
IE843059L IE843059A IE305984A IE843059L IE 843059 L IE843059 L IE 843059L IE 843059 A IE843059 A IE 843059A IE 305984 A IE305984 A IE 305984A IE 843059 L IE843059 L IE 843059L
Authority
IE
Ireland
Prior art keywords
phenoxyethyl
triazolones
ethyl
preparation
gb2185983a
Prior art date
Application number
IE843059A
Other versions
IE74871B1 (en
Inventor
Gary D Madding
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24222593&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE843059(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IE843059L publication Critical patent/IE843059L/en
Priority to IE134288A priority Critical patent/IE63909B1/en
Publication of IE74871B1 publication Critical patent/IE74871B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

In a novel process for the preparation of 5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazolone (used in the synthesis of antidepressant 1,2,4-triazolones typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one, also known as nefazodone), novel intermediate acid addition salts of formula <IMAGE> and processes for their preparation are disclosed.y [GB2185983A]
IE305984A 1983-11-30 1984-11-29 Process for production of 1,2,4-triazolones IE74871B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE134288A IE63909B1 (en) 1983-11-30 1988-05-04 Intermediates in process for production of 1,2,4-triazolones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55672783A 1983-11-30 1983-11-30

Publications (2)

Publication Number Publication Date
IE843059L true IE843059L (en) 1985-05-30
IE74871B1 IE74871B1 (en) 1997-08-13

Family

ID=24222593

Family Applications (1)

Application Number Title Priority Date Filing Date
IE305984A IE74871B1 (en) 1983-11-30 1984-11-29 Process for production of 1,2,4-triazolones

Country Status (25)

Country Link
JP (1) JPS60132969A (en)
KR (1) KR890000990B1 (en)
AT (1) AT387571B (en)
AU (1) AU576338B2 (en)
BE (1) BE901165A (en)
CA (1) CA1233826A (en)
CH (1) CH663613A5 (en)
CY (2) CY1471A (en)
DE (1) DE3443820C2 (en)
DK (3) DK159970C (en)
ES (2) ES8609282A1 (en)
FI (1) FI81785C (en)
FR (1) FR2555582B1 (en)
GB (2) GB2150567B (en)
GR (1) GR81110B (en)
HK (2) HK16289A (en)
IE (1) IE74871B1 (en)
IT (1) IT1178641B (en)
KE (1) KE3852A (en)
LU (1) LU85657A1 (en)
NL (1) NL8403635A (en)
SE (3) SE456993B (en)
SG (1) SG80588G (en)
YU (2) YU44721B (en)
ZA (1) ZA849264B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2182241C (en) * 1996-07-29 2002-09-17 Bo Lei Methods for the manufacture of nefazodone
DE19902960A1 (en) * 1999-01-26 2000-07-27 Bayer Ag Production of high-purity methyl carbazate comprises adding hydrazine and dimethyl carbonate simultaneously to solvent, distilling off solvent and low boilers and purifying product
CA2356450C (en) 2001-09-10 2003-11-25 Brantford Chemicals Inc. An improved process for the preparation of nefazodone hydrochloride

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1126882B (en) * 1960-05-03 1962-04-05 Boehringer Sohn Ingelheim Process for the preparation of 1,2,4-triazolonen- (5)
DE1545646B1 (en) * 1965-12-15 1969-09-18 Boehringer Sohn Ingelheim 1,3-Dimethyl-4- (2 ', 4'-dichlorophenyl) -1,2,4-triazolon- (5) and process for its preparation
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
US4613600A (en) * 1983-09-30 1986-09-23 Mead Johnson & Company Antidepressant 1,2,4-triazolone compounds

Also Published As

Publication number Publication date
YU44721B (en) 1990-12-31
DK70790D0 (en) 1990-03-19
IE74871B1 (en) 1997-08-13
FR2555582B1 (en) 1987-02-27
IT8423808A0 (en) 1984-11-29
SE8801408L (en) 1988-04-15
FR2555582A1 (en) 1985-05-31
DK70890A (en) 1990-03-19
DK70790A (en) 1990-03-19
YU45325B (en) 1992-05-28
GB2150567A (en) 1985-07-03
KR850004244A (en) 1985-07-11
GB8430275D0 (en) 1985-01-09
FI81785C (en) 1990-12-10
FI844647A0 (en) 1984-11-27
HK16289A (en) 1989-03-03
GB2185983B (en) 1988-01-13
GB8702275D0 (en) 1987-03-11
NL8403635A (en) 1985-06-17
DE3443820A1 (en) 1985-06-20
CY1471A (en) 1989-07-21
SG80588G (en) 1989-07-07
IT1178641B (en) 1987-09-09
CH663613A5 (en) 1987-12-31
DK171451B1 (en) 1996-11-04
DK159970B (en) 1991-01-07
JPS60132969A (en) 1985-07-16
DK159970C (en) 1991-05-27
DE3443820C2 (en) 1997-01-09
YU82686A (en) 1986-10-31
YU199884A (en) 1986-10-31
ES8706320A1 (en) 1987-06-16
AU576338B2 (en) 1988-08-25
DK70890D0 (en) 1990-03-19
GB2185983A (en) 1987-08-05
SE464025B (en) 1991-02-25
DK567384D0 (en) 1984-11-29
SE8406045L (en) 1985-05-31
SE456993B (en) 1988-11-21
GR81110B (en) 1985-04-01
ZA849264B (en) 1985-07-31
JPH0516424B2 (en) 1993-03-04
CA1233826A (en) 1988-03-08
FI81785B (en) 1990-08-31
ES553547A0 (en) 1987-06-16
SE8406045D0 (en) 1984-11-29
KE3852A (en) 1989-05-05
FI844647L (en) 1985-05-31
ES538079A0 (en) 1986-07-16
SE8801409D0 (en) 1988-04-15
HK16389A (en) 1989-03-03
ES8609282A1 (en) 1986-07-16
GB2150567B (en) 1988-01-13
KR890000990B1 (en) 1989-04-15
AT387571B (en) 1989-02-10
SE8801408D0 (en) 1988-04-15
SE469894B (en) 1993-10-04
CY1472A (en) 1989-07-21
DK567384A (en) 1985-05-31
SE8801409L (en) 1988-04-15
BE901165A (en) 1985-05-29
AU3609284A (en) 1985-06-06
LU85657A1 (en) 1985-07-17

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Legal Events

Date Code Title Description
MK9A Patent expired