IE831745L - Vitamin d analogs - Google Patents

Vitamin d analogs

Info

Publication number
IE831745L
IE831745L IE831745A IE174583A IE831745L IE 831745 L IE831745 L IE 831745L IE 831745 A IE831745 A IE 831745A IE 174583 A IE174583 A IE 174583A IE 831745 L IE831745 L IE 831745L
Authority
IE
Ireland
Prior art keywords
vitamin
analogs
fluoro
alpha
gb2126234a
Prior art date
Application number
IE831745A
Other versions
IE55801B1 (en
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/401,996 external-priority patent/US4428946A/en
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IE831745L publication Critical patent/IE831745L/en
Publication of IE55801B1 publication Critical patent/IE55801B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Abstract

This invention provides 24-fluoro-1 alpha ,25-dihydroxyvitamin D3 and 24- fluoro-1 alpha ,25-dihydroxy-5,6-trans- vitamin D3 of formulae <IMAGE> where R1, R2 and R3 are hydrogen or acyl.o [GB2126234A]
IE1745/83A 1982-07-26 1983-07-25 Novel vitamin d analogs IE55801B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40199782A 1982-07-26 1982-07-26
US06/401,996 US4428946A (en) 1982-07-26 1982-07-26 Method of preventing milk fever in dairy cattle

Publications (2)

Publication Number Publication Date
IE831745L true IE831745L (en) 1984-01-26
IE55801B1 IE55801B1 (en) 1991-01-16

Family

ID=27017681

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1745/83A IE55801B1 (en) 1982-07-26 1983-07-25 Novel vitamin d analogs

Country Status (4)

Country Link
FR (1) FR2530624B1 (en)
GB (1) GB2126234B (en)
IE (1) IE55801B1 (en)
IT (1) IT1163846B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1272953A (en) * 1984-10-08 1990-08-21 Yuji Makino Pharmaceutical composition for external use containing active-type vitamin d.sub.3
US4853378A (en) * 1986-10-20 1989-08-01 Sumitomo Chemical Company, Limited Fluorine derivatives of vitamin D3 and process for producing the same
AU6441890A (en) * 1989-09-11 1991-04-08 Wisconsin Alumni Research Foundation Novel use of vitamin d compounds to inhibit replication of the aids virus
CA2229316C (en) * 1995-09-21 2005-04-12 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5576858A (en) * 1978-12-04 1980-06-10 Teijin Ltd 24-fluoro-25-hydroxyvitamin d3 or its oh-protected derivative, and their preparation
US4305880A (en) * 1980-09-22 1981-12-15 Wisconsin Alumni Research Foundation Process for preparing 24-fluoro-25-hydroxycholecalciferol
NZ201702A (en) * 1981-08-28 1985-08-16 Hoffmann La Roche 1 alpha,25-dihydroxy-(24r or 24s)-fluorocholecal-ciferol and intermediates;pharmaceutical compositions

Also Published As

Publication number Publication date
FR2530624A1 (en) 1984-01-27
IT8322218A0 (en) 1983-07-25
GB2126234A (en) 1984-03-21
IE55801B1 (en) 1991-01-16
IT1163846B (en) 1987-04-08
GB2126234B (en) 1986-05-21
FR2530624B1 (en) 1987-08-07
GB8319932D0 (en) 1983-08-24

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