IE812500L - Piperidine derivatives - Google Patents
Piperidine derivativesInfo
- Publication number
- IE812500L IE812500L IE812500A IE250081A IE812500L IE 812500 L IE812500 L IE 812500L IE 812500 A IE812500 A IE 812500A IE 250081 A IE250081 A IE 250081A IE 812500 L IE812500 L IE 812500L
- Authority
- IE
- Ireland
- Prior art keywords
- radical
- hydrogen atom
- alkyl
- halogen atoms
- piperidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Piperidine derivatives of the general formula: <IMG> wherein R represents a hydrogen atom, or a (C1-4)alkyl hydroxy(C1-4)alkyl, or (C1-4)alkoxycarbonyl radical or a benzyl radical optionally carrying a substituent selected from halogen atoms and (C1-4)alkoxy radicals or the phenethyl radical, or the 3-phenylpropyl radical, and X represents one or more hydrogen or halogen atoms or (C1-4)alkyl, (C1-4)alkoxy, trifluoromethyl or methylenedioxy radicals, or alternatively X forms with the phenyl nucleus a naphthyl radical, with the proviso that when R represents a hydrogen atom X is other than a hydrogen atom, are new compounds useful as medicaments and, more particularly, as antidepressants. They may be prepared by reaction of a 4-hydroxypiperidine with a benzyl halide.
[CA1173039A]
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA817373A ZA817373B (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives,their preparation and pharmaceutical compositions containing them |
NZ198748A NZ198748A (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives and pharmaceutical compositions |
FI813330A FI77850C (en) | 1981-10-23 | 1981-10-23 | Process for the preparation of 4-benzyloxy or 4-naphthylmethoxypipe ridin derivatives which have antidepressant effect. |
ES506500A ES506500A0 (en) | 1981-10-23 | 1981-10-23 | PIPERIDINE DERIVATIVES PREPARATION PROCEDURE |
PT73875A PT73875B (en) | 1981-10-23 | 1981-10-23 | PROCESS FOR THE PREPARATION OF THERAPEUTICALLY APPLICABLE PIPERIDINE DERIVATIVES |
JP56170536A JPS5872565A (en) | 1981-10-23 | 1981-10-23 | Piperidine derivative and application to medicine |
CA000388595A CA1173039A (en) | 1981-10-23 | 1981-10-23 | 4-benzyloxypiperidine compounds |
GR66337A GR75364B (en) | 1981-10-23 | 1981-10-23 | |
DK469381A DK157853C (en) | 1981-10-23 | 1981-10-23 | ANALOGY PROCEDURE FOR THE PREPARATION OF 4-BENZYLOXYPIPERIDE INGREDIATES |
AU76769/81A AU545739B2 (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives |
IE2500/81A IE51707B1 (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives,their preparation and pharmaceutical compositions containing them |
NO813577A NO153890C (en) | 1981-10-23 | 1981-10-23 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PIPERIDE INGREDIENTS. |
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA817373A ZA817373B (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives,their preparation and pharmaceutical compositions containing them |
NZ198748A NZ198748A (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives and pharmaceutical compositions |
FI813330A FI77850C (en) | 1981-10-23 | 1981-10-23 | Process for the preparation of 4-benzyloxy or 4-naphthylmethoxypipe ridin derivatives which have antidepressant effect. |
ES506500A ES506500A0 (en) | 1981-10-23 | 1981-10-23 | PIPERIDINE DERIVATIVES PREPARATION PROCEDURE |
PT73875A PT73875B (en) | 1981-10-23 | 1981-10-23 | PROCESS FOR THE PREPARATION OF THERAPEUTICALLY APPLICABLE PIPERIDINE DERIVATIVES |
JP56170536A JPS5872565A (en) | 1981-10-23 | 1981-10-23 | Piperidine derivative and application to medicine |
CA000388595A CA1173039A (en) | 1981-10-23 | 1981-10-23 | 4-benzyloxypiperidine compounds |
GR66337A GR75364B (en) | 1981-10-23 | 1981-10-23 | |
DK469381A DK157853C (en) | 1981-10-23 | 1981-10-23 | ANALOGY PROCEDURE FOR THE PREPARATION OF 4-BENZYLOXYPIPERIDE INGREDIATES |
AU76769/81A AU545739B2 (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives |
IE2500/81A IE51707B1 (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives,their preparation and pharmaceutical compositions containing them |
NO813577A NO153890C (en) | 1981-10-23 | 1981-10-23 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PIPERIDE INGREDIENTS. |
Publications (2)
Publication Number | Publication Date |
---|---|
IE812500L true IE812500L (en) | 1983-04-21 |
IE51707B1 IE51707B1 (en) | 1987-02-18 |
Family
ID=27582840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE2500/81A IE51707B1 (en) | 1981-10-23 | 1981-10-23 | Piperidine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS5872565A (en) |
AU (1) | AU545739B2 (en) |
CA (1) | CA1173039A (en) |
DK (1) | DK157853C (en) |
ES (1) | ES506500A0 (en) |
FI (1) | FI77850C (en) |
GR (1) | GR75364B (en) |
IE (1) | IE51707B1 (en) |
NO (1) | NO153890C (en) |
NZ (1) | NZ198748A (en) |
PT (1) | PT73875B (en) |
ZA (1) | ZA817373B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02148948U (en) * | 1989-05-17 | 1990-12-18 | ||
US5169855A (en) * | 1990-03-28 | 1992-12-08 | Du Pont Merck Pharmaceutical Company | Piperidine ether derivatives as psychotropic drugs or plant fungicides |
JPH0535676U (en) * | 1991-06-06 | 1993-05-14 | 株式会社カネマス | Pack for reconstitution of dried seaweed |
-
1981
- 1981-10-23 ES ES506500A patent/ES506500A0/en active Granted
- 1981-10-23 PT PT73875A patent/PT73875B/en unknown
- 1981-10-23 GR GR66337A patent/GR75364B/el unknown
- 1981-10-23 FI FI813330A patent/FI77850C/en not_active IP Right Cessation
- 1981-10-23 NO NO813577A patent/NO153890C/en unknown
- 1981-10-23 IE IE2500/81A patent/IE51707B1/en not_active IP Right Cessation
- 1981-10-23 DK DK469381A patent/DK157853C/en not_active IP Right Cessation
- 1981-10-23 ZA ZA817373A patent/ZA817373B/en unknown
- 1981-10-23 JP JP56170536A patent/JPS5872565A/en active Granted
- 1981-10-23 AU AU76769/81A patent/AU545739B2/en not_active Ceased
- 1981-10-23 CA CA000388595A patent/CA1173039A/en not_active Expired
- 1981-10-23 NZ NZ198748A patent/NZ198748A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI77850C (en) | 1989-05-10 |
ES8206476A1 (en) | 1982-08-16 |
ZA817373B (en) | 1983-03-30 |
FI77850B (en) | 1989-01-31 |
FI813330L (en) | 1983-04-24 |
AU545739B2 (en) | 1985-08-01 |
NO813577L (en) | 1983-04-25 |
GR75364B (en) | 1984-07-13 |
IE51707B1 (en) | 1987-02-18 |
AU7676981A (en) | 1983-04-28 |
JPS5872565A (en) | 1983-04-30 |
NO153890B (en) | 1986-03-03 |
CA1173039A (en) | 1984-08-21 |
JPS6135177B2 (en) | 1986-08-12 |
NO153890C (en) | 1986-06-11 |
PT73875B (en) | 1983-01-25 |
NZ198748A (en) | 1984-08-24 |
DK157853B (en) | 1990-02-26 |
ES506500A0 (en) | 1982-08-16 |
DK469381A (en) | 1983-04-24 |
PT73875A (en) | 1981-11-01 |
DK157853C (en) | 1990-08-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |