IE791023L - Unsaturated fatty acid and derivatives for use in thrombo-¹embolic disease - Google Patents
Unsaturated fatty acid and derivatives for use in thrombo-¹embolic diseaseInfo
- Publication number
- IE791023L IE791023L IE791023A IE102379A IE791023L IE 791023 L IE791023 L IE 791023L IE 791023 A IE791023 A IE 791023A IE 102379 A IE102379 A IE 102379A IE 791023 L IE791023 L IE 791023L
- Authority
- IE
- Ireland
- Prior art keywords
- pharmaceutically acceptable
- 1embolic
- thrombo
- disease
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C15/00—Butter; Butter preparations; Making thereof
- A23C15/12—Butter preparations
- A23C15/126—Butter containing a minority of vegetable oils; Enrichment of butter with fatty acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
- A23D9/013—Other fatty acid esters, e.g. phosphatides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Food Science & Technology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A pharmaceutical composition contains (all-Z)-5,8,11,14,17-eicosapentaenoic acid or one of its pharmaceutically acceptable salts, esters or amides and a pharmaceutically acceptable vehicle. The (all-Z)-5,8,11,14,17-eicosapentaenoic acid or its pharmaceutically acceptable salts, esters or amides can be used for the treatment or prophylaxis of thromboembolic states, to increase the bleeding time, dissolve or disperse thrombi or platelet aggregates which have already formed or to modify or prevent the adhesion of platelets to damaged tissue. They can furthermore be used to treat platelets in order to reduce their tendency to aggregation and/or to increase the rate of their separation from one another. They can furthermore be used as additive to blood in an extracorporeal circulation.
[FR2426461A1]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2357578A GB1604554A (en) | 1978-05-26 | 1978-05-26 | Pharmaceutical and food formulations |
GB2357478 | 1978-05-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE791023L true IE791023L (en) | 1979-11-26 |
IE48287B1 IE48287B1 (en) | 1984-11-28 |
Family
ID=26256599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1023/79A IE48287B1 (en) | 1978-05-26 | 1979-08-08 | Fatty acid and derivatives thereof for use in treatment of prophylaxis of thrombo-embolic conditions |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5515444A (en) |
AU (1) | AU527784B2 (en) |
CA (1) | CA1151068A (en) |
CH (1) | CH644267A5 (en) |
DE (1) | DE2831507A1 (en) |
ES (1) | ES8104983A1 (en) |
FR (1) | FR2426461A1 (en) |
IE (1) | IE48287B1 (en) |
IL (1) | IL55227A (en) |
IT (1) | IT1116505B (en) |
NL (1) | NL191332C (en) |
NZ (1) | NZ187908A (en) |
SE (1) | SE448678B (en) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5735512A (en) * | 1980-06-27 | 1982-02-26 | Nippon Oil & Fats Co Ltd | Preventive and remedy for thrombosis |
JPS59172416A (en) * | 1983-03-18 | 1984-09-29 | Terumo Corp | Fat transfusion solution |
FR2548021B1 (en) * | 1983-06-29 | 1986-02-28 | Dick P R | PROLONGED AND CONTINUOUS DERMAL PHARMACEUTICAL COMPOSITIONS BASED ON ESSENTIAL FATTY ACIDS |
CA1239587A (en) * | 1983-10-24 | 1988-07-26 | David Rubin | Combined fatty acid composition for lowering blood cholestrol and triglyceride levels |
JPS60132916A (en) * | 1983-12-21 | 1985-07-16 | Nisshin Oil Mills Ltd:The | Food or drug for preventing thrombosis |
US4752618A (en) * | 1984-07-12 | 1988-06-21 | New England Deaconess Hospital | Method of minimizing efects of infection through diet |
JPH0748991B2 (en) * | 1984-08-29 | 1995-05-31 | 日本油脂株式会社 | Tube feeding composition |
GB8710780D0 (en) * | 1987-05-07 | 1987-06-10 | Scras | Opthalmological application of eicosapentaenoic acid |
GB8819110D0 (en) * | 1988-08-11 | 1988-09-14 | Norsk Hydro As | Antihypertensive drug & method for production |
US5922345A (en) * | 1990-12-07 | 1999-07-13 | Scotia Holdings Plc | Nutrition |
WO1993020717A2 (en) * | 1992-04-13 | 1993-10-28 | Research Corporation Technologies, Inc. | Reducing gastrointestinal irritation in infant nutrition |
NL9401743A (en) * | 1994-10-20 | 1996-06-03 | Prospa Bv | Salts of amino alcohols and pharmaceutical formulations containing them. |
DE19503993A1 (en) * | 1995-02-08 | 1996-08-14 | Johann Friedrich Dr Med Desaga | Enteral product contg n-3-fatty acid or deriv and medium chain length tri:glyceride |
DE10056351A1 (en) * | 2000-11-14 | 2002-05-29 | Weylandt Karsten Henrich | Pharmaceutical preparation containing omega-3 fatty acids and other active substances e.g. an antiinflammatory, cyclooxygenase II inhibitor, 5-lipoxygenase inhibitor or platelet aggregation inhibitor |
GB0403247D0 (en) | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
EP2424521A4 (en) | 2009-04-29 | 2015-03-04 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
BRPI1011876B1 (en) | 2009-04-29 | 2020-03-31 | Amarin Pharma, Inc. | STABLE PHARMACEUTICAL COMPOSITIONS UNDERSTANDING EICOSAPENTAENOIC ETHYLACID (ETHYL-EPA) AND USE OF THE SAME TO TREAT OR PREVENT A CARDIOVASCULAR DISEASE |
DK2443246T3 (en) | 2009-06-15 | 2018-03-26 | Amarin Pharmaceuticals Ie Ltd | COMPOSITIONS AND METHODS FOR REDUCING TRIGLYCERIDES WITHOUT INCREASING LDL-C LEVELS IN AN INDIVIDUAL WITH CURRENT STATE THERAPY |
RU2012116079A (en) | 2009-09-23 | 2013-10-27 | АМАРИН КОРПОРЕЙШН ПиЭлСи | PHARMACEUTICAL COMPOSITION, INCLUDING OMEGA-3 FATTY ACID AND HYDROXY DERIVATED STATIN AND WAYS OF ITS APPLICATION |
US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
US20130131170A1 (en) | 2011-11-07 | 2013-05-23 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
AU2013207368A1 (en) | 2012-01-06 | 2014-07-24 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering levels of high-sensitivity (hs-CRP) in a subject |
EP4342546A3 (en) | 2012-06-29 | 2024-05-22 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of a cardiovascular event in a subject on statin therapy |
WO2014074552A2 (en) | 2012-11-06 | 2014-05-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy |
US20140187633A1 (en) | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
KR20150115745A (en) | 2013-02-06 | 2015-10-14 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | Methods for reducing aggregate content in protein preparations |
US9452151B2 (en) | 2013-02-06 | 2016-09-27 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing apolipoprotein C-III |
US9624492B2 (en) | 2013-02-13 | 2017-04-18 | Amarin Pharmaceuticals Ireland Limited | Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof |
US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
US20150065572A1 (en) | 2013-09-04 | 2015-03-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing prostate cancer |
US9585859B2 (en) | 2013-10-10 | 2017-03-07 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy |
US10561631B2 (en) | 2014-06-11 | 2020-02-18 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing RLP-C |
US10172818B2 (en) | 2014-06-16 | 2019-01-08 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
US10406130B2 (en) | 2016-03-15 | 2019-09-10 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
TW201900160A (en) | 2017-05-19 | 2019-01-01 | 愛爾蘭商艾瑪琳製藥愛爾蘭有限公司 | Compositions and Methods for Lowering Triglycerides in a Subject Having Reduced Kidney Function |
US11058661B2 (en) | 2018-03-02 | 2021-07-13 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L |
KR20210110890A (en) | 2018-09-24 | 2021-09-09 | 애머린 파마슈티칼스 아일랜드 리미티드 | Methods of reducing the risk of cardiovascular events in a subject |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE319677B (en) * | 1965-03-27 | 1970-01-19 | Sumitomo Chemical Co | |
FR2097036A1 (en) * | 1970-07-29 | 1972-03-03 | Sopharga Lab | Lipids contg fatty acids - for treatment of atheroslerosis |
GB1476624A (en) * | 1973-05-30 | 1977-06-16 | Cepbepe | Tranquiliser medicaments |
GB1580444A (en) * | 1976-11-04 | 1980-12-03 | Bio Oil Res | Pharmaceutical compositions |
JPS6257605A (en) * | 1985-09-05 | 1987-03-13 | Kaizuka Kazutoshi | Method for extracting effective component from multiple-element mineral |
-
1978
- 1978-07-17 AU AU38084/78A patent/AU527784B2/en not_active Expired
- 1978-07-18 DE DE19782831507 patent/DE2831507A1/en active Granted
- 1978-07-19 JP JP8824578A patent/JPS5515444A/en active Pending
- 1978-07-19 NZ NZ187908A patent/NZ187908A/en unknown
- 1978-07-27 IL IL55227A patent/IL55227A/en unknown
-
1979
- 1979-01-19 IT IT47717/79A patent/IT1116505B/en active
- 1979-05-23 FR FR7913122A patent/FR2426461A1/en active Granted
- 1979-05-25 CH CH490379A patent/CH644267A5/en not_active IP Right Cessation
- 1979-05-25 ES ES480921A patent/ES8104983A1/en not_active Expired
- 1979-05-25 SE SE7904570A patent/SE448678B/en not_active IP Right Cessation
- 1979-05-25 NL NL7904144A patent/NL191332C/en not_active IP Right Cessation
- 1979-05-25 CA CA000328419A patent/CA1151068A/en not_active Expired
- 1979-08-08 IE IE1023/79A patent/IE48287B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE448678B (en) | 1987-03-16 |
FR2426461B1 (en) | 1983-02-11 |
ES480921A0 (en) | 1981-05-16 |
CA1151068A (en) | 1983-08-02 |
IE48287B1 (en) | 1984-11-28 |
FR2426461A1 (en) | 1979-12-21 |
NZ187908A (en) | 1984-05-31 |
CH644267A5 (en) | 1984-07-31 |
JPS5515444A (en) | 1980-02-02 |
IL55227A (en) | 1982-12-31 |
AU3808478A (en) | 1980-01-17 |
NL191332B (en) | 1995-01-02 |
DE2831507C2 (en) | 1989-07-13 |
NL191332C (en) | 1995-06-01 |
IT7947717A0 (en) | 1979-01-19 |
NL7904144A (en) | 1979-11-28 |
DE2831507A1 (en) | 1979-11-29 |
SE7904570L (en) | 1979-11-27 |
AU527784B2 (en) | 1983-03-24 |
IT1116505B (en) | 1986-02-10 |
ES8104983A1 (en) | 1981-05-16 |
IL55227A0 (en) | 1978-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK9A | Patent expired |