IE790144L - Encapsulation of medicaments within liposomes - Google Patents
Encapsulation of medicaments within liposomesInfo
- Publication number
- IE790144L IE790144L IE790144A IE14479A IE790144L IE 790144 L IE790144 L IE 790144L IE 790144 A IE790144 A IE 790144A IE 14479 A IE14479 A IE 14479A IE 790144 L IE790144 L IE 790144L
- Authority
- IE
- Ireland
- Prior art keywords
- liposomes
- medicaments
- medicament
- beta
- cholesterol
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 4
- 239000002502 liposome Substances 0.000 title abstract 3
- 238000005538 encapsulation Methods 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- QYIXCDOBOSTCEI-QCYZZNICSA-N (5alpha)-cholestan-3beta-ol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-QCYZZNICSA-N 0.000 abstract 1
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17beta-estradiol Natural products OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- YIKKMWSQVKJCOP-ABXCMAEBSA-N 7-ketocholesterol Chemical compound C1C[C@H](O)CC2=CC(=O)[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]3[C@]21C YIKKMWSQVKJCOP-ABXCMAEBSA-N 0.000 abstract 1
- BDCFUHIWJODVNG-UHFFFAOYSA-N Desmosterol Natural products C1C=C2CC(O)C=CC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 BDCFUHIWJODVNG-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- ZPXSCAKFGYXMGA-UHFFFAOYSA-N Mazindol Chemical compound N12CCN=C2C2=CC=CC=C2C1(O)C1=CC=C(Cl)C=C1 ZPXSCAKFGYXMGA-UHFFFAOYSA-N 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- -1 aliphatic lipid Chemical class 0.000 abstract 1
- QYIXCDOBOSTCEI-UHFFFAOYSA-N alpha-cholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 QYIXCDOBOSTCEI-UHFFFAOYSA-N 0.000 abstract 1
- 229940076810 beta sitosterol Drugs 0.000 abstract 1
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 abstract 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- AVSXSVCZWQODGV-DPAQBDIFSA-N desmosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@@H](CCC=C(C)C)C)[C@@]1(C)CC2 AVSXSVCZWQODGV-DPAQBDIFSA-N 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229960003133 ergot alkaloid Drugs 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 239000004973 liquid crystal related substance Substances 0.000 abstract 1
- 229960000299 mazindol Drugs 0.000 abstract 1
- 239000000693 micelle Substances 0.000 abstract 1
- VOXZDWNPVJITMN-WKUFJEKOSA-N oestradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-WKUFJEKOSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 159000000001 potassium salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 abstract 1
- 229950005143 sitosterol Drugs 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87283578A | 1978-01-27 | 1978-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IE790144L true IE790144L (en) | 1979-07-27 |
Family
ID=25360392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE790144A IE790144L (en) | 1978-01-27 | 1979-01-30 | Encapsulation of medicaments within liposomes |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS54113417A (en, 2012) |
| AT (1) | AT368888B (en, 2012) |
| AU (1) | AU524529B2 (en, 2012) |
| BE (1) | BE873715A (en, 2012) |
| CA (1) | CA1111347A (en, 2012) |
| DE (1) | DE2902672A1 (en, 2012) |
| DK (1) | DK22879A (en, 2012) |
| ES (1) | ES477217A1 (en, 2012) |
| FI (1) | FI790164A7 (en, 2012) |
| FR (1) | FR2415460A1 (en, 2012) |
| GB (1) | GB2013087B (en, 2012) |
| IE (1) | IE790144L (en, 2012) |
| IL (1) | IL56499A (en, 2012) |
| IT (1) | IT1109867B (en, 2012) |
| NL (1) | NL7900545A (en, 2012) |
| NZ (1) | NZ189477A (en, 2012) |
| PT (1) | PT69132A (en, 2012) |
| SE (1) | SE7900458L (en, 2012) |
| ZA (1) | ZA79349B (en, 2012) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2026340B (en) * | 1978-07-03 | 1982-12-22 | Ash P | Stabilising microvesicles |
| JPS5874619A (ja) * | 1981-10-29 | 1983-05-06 | Nippon Shinyaku Co Ltd | リポソ−ム及びその製法 |
| DE3374837D1 (en) * | 1982-02-17 | 1988-01-21 | Ciba Geigy Ag | Lipids in the aqueous phase |
| EP0102324A3 (de) * | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
| DE3421468A1 (de) * | 1984-06-08 | 1985-12-19 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung |
| US4849227A (en) * | 1986-03-21 | 1989-07-18 | Eurasiam Laboratories, Inc. | Pharmaceutical compositions |
| US5077211A (en) * | 1988-07-06 | 1991-12-31 | Applied Genetics, Inc. | Purification and administration of dna repair enzymes |
| WO1992003123A1 (en) * | 1990-08-28 | 1992-03-05 | Liposome Technology, Inc. | Liposome alternative bilayer formulations |
| FR2714621B1 (fr) * | 1994-01-06 | 1996-02-23 | Centre Nat Rech Scient | Procédé de préparation de liposomes sans utilisation de solvant organique. |
| US7157254B1 (en) | 1999-08-13 | 2007-01-02 | Suntory Limited | Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the mircroorganism |
| JP4088097B2 (ja) | 2002-04-26 | 2008-05-21 | サントリー株式会社 | 高度不飽和脂肪酸含有脂質の製造方法 |
| AU2013203682B2 (en) * | 2011-08-25 | 2016-03-31 | Trophos | Liposome comprising at least one cholesterol derivative |
| FR2979239A1 (fr) * | 2011-08-25 | 2013-03-01 | Trophos | Liposome comprenant au moins un derive de cholesterol |
| CN113967192A (zh) * | 2021-11-09 | 2022-01-25 | 陕西海斯夫生物工程有限公司 | 一种用于加速伤口愈合的药物组合物、它们的制备方法与用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957951A (en) * | 1974-08-23 | 1976-05-18 | International Telephone And Telegraph Corporation | Process for removing contaminants from hot waste gas streams |
| FR2315991A1 (fr) * | 1975-06-30 | 1977-01-28 | Oreal | Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes |
| FR2408387A2 (fr) * | 1975-06-30 | 1979-06-08 | Oreal | Compositions a base de dispersions aqueuses de spherules lipidiques |
| FR2374910A1 (fr) * | 1976-10-23 | 1978-07-21 | Choay Sa | Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations |
-
1979
- 1979-01-18 DK DK22879A patent/DK22879A/da not_active Application Discontinuation
- 1979-01-18 FI FI790164A patent/FI790164A7/fi unknown
- 1979-01-18 SE SE7900458A patent/SE7900458L/ not_active Application Discontinuation
- 1979-01-24 NL NL7900545A patent/NL7900545A/xx not_active Application Discontinuation
- 1979-01-24 DE DE19792902672 patent/DE2902672A1/de not_active Withdrawn
- 1979-01-25 BE BE0/193081A patent/BE873715A/xx not_active IP Right Cessation
- 1979-01-25 CA CA320,271A patent/CA1111347A/en not_active Expired
- 1979-01-25 AU AU43678/79A patent/AU524529B2/en not_active Ceased
- 1979-01-25 NZ NZ189477A patent/NZ189477A/xx unknown
- 1979-01-25 IL IL56499A patent/IL56499A/xx unknown
- 1979-01-26 ES ES477217A patent/ES477217A1/es not_active Expired
- 1979-01-26 IT IT19649/79A patent/IT1109867B/it active
- 1979-01-26 ZA ZA79349A patent/ZA79349B/xx unknown
- 1979-01-26 AT AT0058979A patent/AT368888B/de not_active IP Right Cessation
- 1979-01-26 PT PT7969132A patent/PT69132A/pt unknown
- 1979-01-26 FR FR7901999A patent/FR2415460A1/fr active Granted
- 1979-01-26 JP JP730779A patent/JPS54113417A/ja active Pending
- 1979-01-26 GB GB7902881A patent/GB2013087B/en not_active Expired
- 1979-01-30 IE IE790144A patent/IE790144L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT368888B (de) | 1982-11-25 |
| ZA79349B (en) | 1980-09-24 |
| ES477217A1 (es) | 1980-04-01 |
| PT69132A (fr) | 1979-02-01 |
| DE2902672A1 (de) | 1979-08-02 |
| GB2013087B (en) | 1982-07-21 |
| FR2415460B1 (en, 2012) | 1983-05-20 |
| FR2415460A1 (fr) | 1979-08-24 |
| ATA58979A (de) | 1982-04-15 |
| IL56499A0 (en) | 1979-03-12 |
| SE7900458L (sv) | 1979-07-28 |
| BE873715A (fr) | 1979-07-25 |
| IT7919649A0 (it) | 1979-01-26 |
| NL7900545A (nl) | 1979-07-31 |
| FI790164A7 (fi) | 1979-07-28 |
| GB2013087A (en) | 1979-08-08 |
| AU4367879A (en) | 1979-08-02 |
| IT1109867B (it) | 1985-12-23 |
| AU524529B2 (en) | 1982-09-23 |
| NZ189477A (en) | 1981-05-01 |
| CA1111347A (en) | 1981-10-27 |
| DK22879A (da) | 1979-07-28 |
| IL56499A (en) | 1981-09-13 |
| JPS54113417A (en) | 1979-09-05 |
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