IE781354L - Amido-benzylpyrimidines - Google Patents

Amido-benzylpyrimidines

Info

Publication number
IE781354L
IE781354L IE781354A IE135478A IE781354L IE 781354 L IE781354 L IE 781354L IE 781354 A IE781354 A IE 781354A IE 135478 A IE135478 A IE 135478A IE 781354 L IE781354 L IE 781354L
Authority
IE
Ireland
Prior art keywords
pyrimidin
methyl
methoxy
benzyl
see diagramm
Prior art date
Application number
IE781354A
Other versions
IE47022B1 (en
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of IE781354L publication Critical patent/IE781354L/en
Publication of IE47022B1 publication Critical patent/IE47022B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1. Amidino-benzylpyrimidines of the general formula I see diagramm : EP0000336,P9,F1 where R**1 , R**2 , and R**3 , which may be identical or different, are hydrogen, methyl, methoxy or chlorine, R**4 is alkyl of 1 to 6 carbon atoms or benzyl and R**5 and R**6 , which may be identical or different, are hydrogen, lower alkyl of 1 to 4 carbon atoms, trimethoxybenzyl, benzyl or phenyl, cyclohexyl, adamantyl or furfuryl, or one of the radicals R**5 and R**6 is -C6 H4 -SO2 -NH-R**7 , where R**7 is see diagramm : EP0000336,P9,F2 see diagramm : EP0000336,P9,F3 or pyrimidin-2-yl, 4-methyl-pyrimidin-2-yl, 5-methyl-pyrimidin-2-yl, 5-isopropyl-pyrimidin-2-yl, 5-methoxy-pyrimidin-2-yl, 6-methoxy-pyridazin-3-yl, 3-methoxy-pyrazin-2-yl, 5-methyl-isoxazol-3-yl or 2-pyridinyl, or R**5 and R**6 together with the nitrogen to which they are bonded are a saturated heterocyclic ring of 5-7 members, which may contain an oxygen atom or the N-Y group, where Y is methyl, benzyl or phenyl, and their pharmacologically acceptable salts with acids conventionally used for this purpose. [EP0000336A1]
IE1354/78A 1977-07-15 1978-07-05 Novel amidino-benzylpyrimidines, processes for their manufacture and drugs containing the said compounds IE47022B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772732029 DE2732029A1 (en) 1977-07-15 1977-07-15 NEW AMIDINO-BENZYLPYRIMIDINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THEM

Publications (2)

Publication Number Publication Date
IE781354L true IE781354L (en) 1979-01-15
IE47022B1 IE47022B1 (en) 1983-11-30

Family

ID=6014014

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1354/78A IE47022B1 (en) 1977-07-15 1978-07-05 Novel amidino-benzylpyrimidines, processes for their manufacture and drugs containing the said compounds

Country Status (15)

Country Link
EP (1) EP0000336B1 (en)
JP (1) JPS5419986A (en)
AR (1) AR227759A1 (en)
AT (1) AT360999B (en)
AU (1) AU520820B2 (en)
CA (1) CA1129410A (en)
DE (2) DE2732029A1 (en)
DK (1) DK143273C (en)
FI (1) FI782221A (en)
HU (1) HU179408B (en)
IE (1) IE47022B1 (en)
IL (1) IL55063A0 (en)
IT (1) IT1096976B (en)
NO (1) NO782455L (en)
ZA (1) ZA784012B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2730468A1 (en) * 1977-07-06 1979-01-18 Basf Ag NEW N-PYRIMIDINYL IMIDIC ACID ESTERS, PROCESS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THEM
US4333936A (en) * 1978-07-03 1982-06-08 Basf Aktiengesellschaft Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof
DE3045720A1 (en) * 1980-12-04 1982-07-08 Basf Ag, 6700 Ludwigshafen N-PYRIMIDINYL-CARBAMINE ACID ESTER, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
JPS5915110U (en) * 1982-07-22 1984-01-30 クラリオン株式会社 constant voltage circuit
JPH0618012B2 (en) * 1983-01-25 1994-03-09 セイコーエプソン株式会社 Constant voltage circuit

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4849791A (en) * 1971-10-26 1973-07-13

Also Published As

Publication number Publication date
EP0000336A1 (en) 1979-01-24
ATA513078A (en) 1980-07-15
DE2860614D1 (en) 1981-05-07
AU3790378A (en) 1980-01-17
DK143273C (en) 1981-11-30
IT7825382A0 (en) 1978-07-05
CA1129410A (en) 1982-08-10
DK315878A (en) 1979-01-16
AU520820B2 (en) 1982-03-04
EP0000336B1 (en) 1981-04-15
HU179408B (en) 1982-10-28
ZA784012B (en) 1979-08-29
DE2732029A1 (en) 1979-02-01
FI782221A (en) 1979-01-16
IL55063A0 (en) 1978-09-29
IE47022B1 (en) 1983-11-30
NO782455L (en) 1979-01-16
JPS5419986A (en) 1979-02-15
AR227759A1 (en) 1982-12-15
AT360999B (en) 1981-02-10
DK143273B (en) 1981-08-03
IT1096976B (en) 1985-08-26

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