IE48766B1 - Compositions useful in the preparation of stabilized radiographic scanning agents,a method of preparing them and the use of stannous gentisylate as stabilizer in these compositions - Google Patents

Compositions useful in the preparation of stabilized radiographic scanning agents,a method of preparing them and the use of stannous gentisylate as stabilizer in these compositions

Info

Publication number
IE48766B1
IE48766B1 IE1204/79A IE120479A IE48766B1 IE 48766 B1 IE48766 B1 IE 48766B1 IE 1204/79 A IE1204/79 A IE 1204/79A IE 120479 A IE120479 A IE 120479A IE 48766 B1 IE48766 B1 IE 48766B1
Authority
IE
Ireland
Prior art keywords
stabilizer
acid
pertechnetate
salts
soluble
Prior art date
Application number
IE1204/79A
Other languages
English (en)
Other versions
IE791204L (en
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of IE791204L publication Critical patent/IE791204L/xx
Publication of IE48766B1 publication Critical patent/IE48766B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/025—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus inorganic Tc complexes or compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IE1204/79A 1978-06-28 1979-08-08 Compositions useful in the preparation of stabilized radiographic scanning agents,a method of preparing them and the use of stannous gentisylate as stabilizer in these compositions IE48766B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/920,082 US4232000A (en) 1978-06-28 1978-06-28 Radioactive scanning agents with stabilizer

Publications (2)

Publication Number Publication Date
IE791204L IE791204L (en) 1979-12-28
IE48766B1 true IE48766B1 (en) 1985-05-15

Family

ID=25443124

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1204/79A IE48766B1 (en) 1978-06-28 1979-08-08 Compositions useful in the preparation of stabilized radiographic scanning agents,a method of preparing them and the use of stannous gentisylate as stabilizer in these compositions

Country Status (8)

Country Link
US (1) US4232000A (https=)
EP (1) EP0006659B1 (https=)
JP (1) JPS5536796A (https=)
AU (1) AU521704B2 (https=)
CA (1) CA1118683A (https=)
DE (1) DE2962552D1 (https=)
IE (1) IE48766B1 (https=)
NZ (1) NZ190820A (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4432963A (en) * 1978-07-31 1984-02-21 Mallinckrodt, Inc. Radiographic scanning agent
US4515766A (en) * 1980-06-23 1985-05-07 The Massachusetts General Hospital Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium
JPS5750928A (en) * 1980-09-13 1982-03-25 Nippon Mejifuijitsukusu Kk Diagnostic agent for scanning bone
DE78642T1 (de) * 1981-10-30 1983-10-27 Amersham International Plc, Amersham, Buckinghamshire Radiopharmazeutische zubereitung auf grund von technetium-99m und reagenz zur herstellung derselben.
JPS5896031A (ja) * 1981-12-03 1983-06-07 Nippon Mejifuijitsukusu Kk 放射性診断剤およびその製造用組成物
DE3370443D1 (en) 1982-06-10 1987-04-30 Mallinckrodt Inc Radiographic imaging agents
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
US4510125A (en) * 1982-12-08 1985-04-09 Mallinckrodt, Inc. Process for making lyophilized radiographic imaging kit
US4897255A (en) * 1985-01-14 1990-01-30 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US5175343A (en) * 1985-01-14 1992-12-29 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US4853209A (en) * 1987-05-18 1989-08-01 The Dow Chemical Company Bone marrow suppressing agents
US5355245A (en) * 1988-02-12 1994-10-11 Donnelly Corporation Ultraviolet protected electrochemichromic rearview mirror
US5202451A (en) * 1988-02-17 1993-04-13 Neorx Corporation Anchimeric radiometal chelating compounds
JP3038339B2 (ja) * 1988-05-02 2000-05-08 ザイナクシス・テクノロジーズ・インコーポレーテッド バイオ粒子の表面膜に対してバイオアフェクティング物質を結合する化合物
WO1991004057A1 (en) * 1989-09-22 1991-04-04 Neorx Corporation Stable therapeutic radionuclide compositions and methods for preparation thereof
DK0600992T3 (da) * 1991-08-29 2000-10-09 Mallinckrodt Medical Inc Anvendelse af gentissyre eller gentisylalkohol til stabilisering af radiomærkede peptider og proteiner
US6359119B1 (en) * 2000-05-24 2002-03-19 Mallinckrodt Inc. Formulation of Tc and Re carbonyl complexes using stannous ion as the reductant for pertechnetate and perrhenate
US6989138B2 (en) 2000-10-24 2006-01-24 Diatide, Inc. Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans
US6902718B2 (en) * 2000-10-24 2005-06-07 Diatide, Inc. Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
US6881396B2 (en) * 2000-10-24 2005-04-19 Diatide, Inc. Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy-chromans
US7018614B2 (en) 2002-11-05 2006-03-28 Eastern Isotopes, Inc. Stabilization of radiopharmaceuticals labeled with 18-F
CA2526556C (en) * 2003-07-24 2012-09-25 Bracco Imaging S.P.A. Stable radiopharmaceutical compositions and methods for their preparation
JP4844471B2 (ja) 2007-05-14 2011-12-28 株式会社ジェイテクト 十字軸継手

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091088A (en) * 1975-02-19 1978-05-23 Australian Atomic Energy Commission Phenolic amino-carboxylic acid complexes for forming radiopharmaceuticals
US4062933A (en) * 1975-05-27 1977-12-13 Mallinckrodt, Inc. Colloidal compositions with protective agents suitable for radioactive labeling
DE2543350C2 (de) * 1975-09-29 1984-10-11 Henkel KGaA, 4000 Düsseldorf Präparate zur Herstellung von ↑9↑↑9↑↑m↑ Technetium-Radiodiagnostika
DE2543349C2 (de) * 1975-09-29 1984-05-10 Henkel KGaA, 4000 Düsseldorf Preaparate zur herstellung von99m technetium-radiagnostica
US4071613A (en) * 1976-02-26 1978-01-31 Abbott Laboratories Stabilized alcohol solution of reducing salt formulations for use in preparing radioisotope labeled scanning agents: liver scanning technetium-99m colloid and method of preparation

Also Published As

Publication number Publication date
EP0006659B1 (en) 1982-04-21
JPS5536796A (en) 1980-03-14
US4232000A (en) 1980-11-04
DE2962552D1 (en) 1982-06-03
CA1118683A (en) 1982-02-23
AU4845979A (en) 1980-01-03
JPS636528B2 (https=) 1988-02-10
EP0006659A1 (en) 1980-01-09
IE791204L (en) 1979-12-28
AU521704B2 (en) 1982-04-22
NZ190820A (en) 1986-07-11

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Legal Events

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MM4A Patent lapsed