IE45932L - Chromotographic resolving zones - Google Patents

Chromotographic resolving zones

Info

Publication number
IE45932L
IE45932L IE248377A IE248377A IE45932L IE 45932 L IE45932 L IE 45932L IE 248377 A IE248377 A IE 248377A IE 248377 A IE248377 A IE 248377A IE 45932 L IE45932 L IE 45932L
Authority
IE
Ireland
Prior art keywords
pore size
distribution
bimodal
macroparticles
diameter
Prior art date
Application number
IE248377A
Other versions
IE45932B1 (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/826,171 external-priority patent/US4160728A/en
Application filed by Du Pont filed Critical Du Pont
Publication of IE45932L publication Critical patent/IE45932L/en
Publication of IE45932B1 publication Critical patent/IE45932B1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28088—Pore-size distribution
    • B01J20/28092—Bimodal, polymodal, different types of pores or different pore size distributions in different parts of the sorbent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3295—Coatings made of particles, nanoparticles, fibers, nanofibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/525—Physical parameters structural properties surface properties, e.g. porosity

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

The powder for chromatographic separations is used in the separating zone of chromatographs. It essentially contains a multiplicity of separate porous macroparticles, each of which has a mean diameter of 0.5 to 500 mu m. The powder has a bimodal pore size distribution, the mean pore size for each distribution mode being such that the straight-line portions of the molecular weight calibration curve for each pore size in the bimodal distribution essentially do not intersect. Each distribution mode has a pore volume which is such that these straight-line portions run essentially parallel. At the same time, the mean pore sizes of the components of the bimodal distribution are separated by approximately an order of magnitude. The component of the bimodal distribution having the smaller mean pore size accounts for 30 to 60% of the total pore volume and the component of the bimodal distribution having the larger mean pore size accounts for 70 to 40% of it. The macroparticles are superficially porous and have an impermeable core. They have an envelope composed of a multiplicity of identical single layers made up of colloidal microparticles which touch one another and surround the core and which have a diameter of 0.005 to 1.0 mu m. The macroparticles have a diameter of 5 to 500 mu m and are composed mainly of silicon dioxide. <IMAGE> [GB1592885A]
IE248377A 1976-12-08 1977-12-07 Bimodal chromatographic resolving zone IE45932B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74876976A 1976-12-08 1976-12-08
US05/826,171 US4160728A (en) 1976-12-08 1977-08-22 Bimodal chromatographic resolving zone

Publications (2)

Publication Number Publication Date
IE45932L true IE45932L (en) 1978-06-08
IE45932B1 IE45932B1 (en) 1982-12-29

Family

ID=27114997

Family Applications (1)

Application Number Title Priority Date Filing Date
IE248377A IE45932B1 (en) 1976-12-08 1977-12-07 Bimodal chromatographic resolving zone

Country Status (12)

Country Link
JP (1) JPS5371899A (en)
CA (1) CA1101827A (en)
CH (1) CH634661A5 (en)
DE (1) DE2754252A1 (en)
DK (1) DK544977A (en)
FR (1) FR2373316B1 (en)
GB (1) GB1592885A (en)
IE (1) IE45932B1 (en)
IT (1) IT1089344B (en)
LU (1) LU78658A1 (en)
NL (1) NL7713517A (en)
SE (1) SE442591B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2506165B (en) * 2012-09-24 2017-04-12 Thermo Electron Mfg Ltd Improvements in and relating to chromatography columns
GB2506166B (en) * 2012-09-24 2014-12-17 Thermo Electron Mfg Ltd Improvements in and relating to chromatography columns

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3505785A (en) * 1967-06-20 1970-04-14 Du Pont Superficially porous supports for chromatography

Also Published As

Publication number Publication date
NL7713517A (en) 1978-06-12
SE7713892L (en) 1978-06-09
DK544977A (en) 1978-06-09
CH634661A5 (en) 1983-02-15
GB1592885A (en) 1981-07-08
IT1089344B (en) 1985-06-18
IE45932B1 (en) 1982-12-29
LU78658A1 (en) 1978-07-11
SE442591B (en) 1986-01-20
FR2373316B1 (en) 1985-07-19
FR2373316A1 (en) 1978-07-07
JPS6410779B2 (en) 1989-02-22
CA1101827A (en) 1981-05-26
JPS5371899A (en) 1978-06-26
DE2754252A1 (en) 1978-06-15
DE2754252C2 (en) 1989-03-09

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