IE44534L - 11ß-ACETYL-3,20-DIKETOPREGNENES - Google Patents
11ß-ACETYL-3,20-DIKETOPREGNENESInfo
- Publication number
- IE44534L IE44534L IE761942A IE194276A IE44534L IE 44534 L IE44534 L IE 44534L IE 761942 A IE761942 A IE 761942A IE 194276 A IE194276 A IE 194276A IE 44534 L IE44534 L IE 44534L
- Authority
- IE
- Ireland
- Prior art keywords
- diketopregnenes
- acetyl
- alkyl
- group
- inflummatory
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- WJYGBTBQRPGPTC-GLRFCKCYSA-N (8r,9s,10s,13s,14s)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15-dodecahydrocyclopenta[a]phenanthren-3-one Chemical class C1CC2CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC=C(C(=O)C)[C@@]1(C)CC2 WJYGBTBQRPGPTC-GLRFCKCYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229910052736 halogen Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
3,20-Diketopregnenes having in tho 110-position a group of the formula wherein R1 is alkyl and R2 is hydrogen, alkyl, alkoxy, or halogen, and having a cyclic 16,17-acetal or metal group, have useful anti-inflummatory activity.
[CA1058161A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/610,955 US3976637A (en) | 1975-09-08 | 1975-09-08 | 3,20-Diketopregnenes having an 11β-acetal group |
| US66817776A | 1976-03-18 | 1976-03-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE44534L true IE44534L (en) | 1977-03-08 |
| IE44534B1 IE44534B1 (en) | 1981-12-30 |
Family
ID=27086400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1942/76A IE44534B1 (en) | 1975-09-08 | 1976-08-31 | Ethers of 11 -hydroxy steroids and processes for the preparation thereof |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5233664A (en) |
| AU (1) | AU506546B2 (en) |
| BE (1) | BE845943A (en) |
| CA (1) | CA1058161A (en) |
| CH (2) | CH616437A5 (en) |
| DE (1) | DE2640490A1 (en) |
| DK (1) | DK402676A (en) |
| FR (1) | FR2322607A1 (en) |
| GB (1) | GB1544512A (en) |
| IE (1) | IE44534B1 (en) |
| NL (1) | NL7609912A (en) |
| NO (2) | NO144491C (en) |
| SE (1) | SE7609884L (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1285770B1 (en) | 1996-10-04 | 1998-06-18 | Nicox Sa | CORTICOID COMPOUNDS |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3976637A (en) * | 1975-09-08 | 1976-08-24 | E. R. Squibb & Sons, Inc. | 3,20-Diketopregnenes having an 11β-acetal group |
-
1976
- 1976-08-31 IE IE1942/76A patent/IE44534B1/en unknown
- 1976-08-31 CA CA260,229A patent/CA1058161A/en not_active Expired
- 1976-09-02 AU AU17384/76A patent/AU506546B2/en not_active Expired
- 1976-09-06 GB GB36853/76A patent/GB1544512A/en not_active Expired
- 1976-09-07 NO NO76763060A patent/NO144491C/en unknown
- 1976-09-07 NL NL7609912A patent/NL7609912A/en not_active Application Discontinuation
- 1976-09-07 DK DK402676A patent/DK402676A/en unknown
- 1976-09-07 SE SE7609884A patent/SE7609884L/en unknown
- 1976-09-07 CH CH1133976A patent/CH616437A5/en not_active IP Right Cessation
- 1976-09-08 FR FR7627002A patent/FR2322607A1/en active Granted
- 1976-09-08 JP JP51108717A patent/JPS5233664A/en active Pending
- 1976-09-08 BE BE170429A patent/BE845943A/en not_active IP Right Cessation
- 1976-09-08 DE DE19762640490 patent/DE2640490A1/en not_active Withdrawn
-
1979
- 1979-07-04 CH CH626779A patent/CH618186A5/en not_active IP Right Cessation
-
1981
- 1981-01-27 NO NO81810271A patent/NO145919C/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO145919B (en) | 1982-03-15 |
| NO144491C (en) | 1981-09-09 |
| DE2640490A1 (en) | 1977-03-10 |
| NO810271L (en) | 1977-03-09 |
| SE7609884L (en) | 1977-03-09 |
| CH618186A5 (en) | 1980-07-15 |
| NO145919C (en) | 1982-06-30 |
| NL7609912A (en) | 1977-03-10 |
| JPS5233664A (en) | 1977-03-14 |
| CH616437A5 (en) | 1980-03-31 |
| CA1058161A (en) | 1979-07-10 |
| GB1544512A (en) | 1979-04-19 |
| FR2322607A1 (en) | 1977-04-01 |
| IE44534B1 (en) | 1981-12-30 |
| NO763060L (en) | 1977-03-09 |
| FR2322607B1 (en) | 1979-02-23 |
| AU1738476A (en) | 1978-03-09 |
| NO144491B (en) | 1981-06-01 |
| AU506546B2 (en) | 1980-01-10 |
| BE845943A (en) | 1977-03-08 |
| DK402676A (en) | 1977-03-09 |
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