IE41799L - Process for preparing 3-methyl-4-(5-tetrazolyl)-ceph-3-em¹compounds - Google Patents

Process for preparing 3-methyl-4-(5-tetrazolyl)-ceph-3-em¹compounds

Info

Publication number
IE41799L
IE41799L IE752059A IE205975A IE41799L IE 41799 L IE41799 L IE 41799L IE 752059 A IE752059 A IE 752059A IE 205975 A IE205975 A IE 205975A IE 41799 L IE41799 L IE 41799L
Authority
IE
Ireland
Prior art keywords
tetrazolyl
methyl
amino
tertiary
cephems
Prior art date
Application number
IE752059A
Other versions
IE41799B1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE41799L publication Critical patent/IE41799L/en
Publication of IE41799B1 publication Critical patent/IE41799B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

6-Amino-2,2-dimethyl-3-(5-tetrazolyl)penam sulfoxides, 6-(N-protected amino)-2,2-dimethyl-3-(5-tetrazolyl)penam sulfoxides and their direct conversion to 7-amino-3-methyl-4-(5-tetra-zolyl)-.DELTA.3-cephems and 7-(N-protected amino)-3-methyl-4-(5-tetra-zolyl)-.DELTA.3-cephems, useful antibacterial agents or intermediates for antibacterial agents, by heating under acid conditions, desirably in a liquid medium and especially one derived from a tertiary carboxamide, a tertiary urea derivative or a tertiary sulfonamide. The preparation of the tetrazolylpenam sulfoxide reactants is described. [CA1050010A]
IE2059/75A 1974-11-06 1975-09-19 Process for preparing 3-methyl-4-(5-tetrazolyl)- 3-cephem compounds IE41799B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52144474A 1974-11-06 1974-11-06

Publications (2)

Publication Number Publication Date
IE41799L true IE41799L (en) 1976-05-06
IE41799B1 IE41799B1 (en) 1980-03-26

Family

ID=24076758

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2059/75A IE41799B1 (en) 1974-11-06 1975-09-19 Process for preparing 3-methyl-4-(5-tetrazolyl)- 3-cephem compounds

Country Status (11)

Country Link
JP (1) JPS5170790A (en)
BE (1) BE835299A (en)
CA (1) CA1050010A (en)
DE (1) DE2546503A1 (en)
DK (1) DK496975A (en)
ES (2) ES442360A1 (en)
FR (1) FR2290445A1 (en)
GB (2) GB1520479A (en)
IE (1) IE41799B1 (en)
LU (1) LU73730A1 (en)
NL (1) NL7512960A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699904A (en) * 1985-07-01 1987-10-13 Merck & Co., Inc. Tetrazolyl derivatives of β-lactams useful as elastase inhibitors
US4845088A (en) * 1985-07-01 1989-07-04 Merck & Co., Inc. Tetrazolyl derivatives of beta-lactams useful as elastase inhibitors
WO2012147773A1 (en) * 2011-04-28 2012-11-01 塩野義製薬株式会社 Novel cephem compound having catechol or pseudo-catechol structure

Also Published As

Publication number Publication date
BE835299A (en) 1976-05-05
ES442360A1 (en) 1977-04-01
DE2546503A1 (en) 1976-05-13
DK496975A (en) 1976-05-07
JPS5170790A (en) 1976-06-18
IE41799B1 (en) 1980-03-26
FR2290445A1 (en) 1976-06-04
LU73730A1 (en) 1976-09-06
NL7512960A (en) 1976-05-10
GB1520479A (en) 1978-08-09
GB1520480A (en) 1978-08-09
ES451958A1 (en) 1977-10-01
FR2290445B1 (en) 1978-05-12
CA1050010A (en) 1979-03-06

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