IE40915L - 5-nitroimidazole derivatives - Google Patents
5-nitroimidazole derivativesInfo
- Publication number
- IE40915L IE40915L IE750800A IE80075A IE40915L IE 40915 L IE40915 L IE 40915L IE 750800 A IE750800 A IE 750800A IE 80075 A IE80075 A IE 80075A IE 40915 L IE40915 L IE 40915L
- Authority
- IE
- Ireland
- Prior art keywords
- alkaline earth
- group
- alkali metal
- earth metal
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
1446301 5-Nitroimidazole derivatives CRC COMPAGNIA DI RICERCA CHIMICA SA 9 April 1975 [19 April 1974] 14518/75 Heading C2C A process for the preparation of 5-nitroimidazole derivatives of the formula wherein R is (C 1 -C 4 )alkyl; R 1 is hydrogen, an alkali metal or alkaline earth metal, (C 1 -C 4 ). alkyl or a group OM wherein M is an alkali metal or alkaline earth metal; A is oxygen and n is 0 or 1, comprises reacting a compound of the formula wherein # is a 2<SP>1</SP>-haloethyl group, an alkali metal or alkaline earth metal salt of an ethylsulphino or ethylmercapto group, or the radical of a variegated salt -CH 2 CH 2 S 2 O 3 M; with a compound of the formula ZR 2 wherein Z is a halogen atom or the alkali metal or alkaline earth metal salt or a sulphino group, or, where R 2 is a sulphydryl group, an alkali metal or alkaline earth metal atom, and Z is different from B, and R 2 is (C 2 -C 4 )alkyl, or if Z is an alkali metal or alkaline earth metal, a sulphydryl group, and, if desired, oxidizing the resultant compound wherein n is zero to one wherein n is 1 suitably in the presence of lithium perchlorate in an electrical cell.
[GB1446301A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH545974A CH605811A5 (en) | 1974-04-19 | 1974-04-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40915L true IE40915L (en) | 1975-10-19 |
| IE40915B1 IE40915B1 (en) | 1979-09-12 |
Family
ID=4293954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE800/75A IE40915B1 (en) | 1974-04-19 | 1975-04-09 | Preparation of 5-nitroimidazole derivatives |
Country Status (20)
| Country | Link |
|---|---|
| JP (2) | JPS5314073B2 (en) |
| AR (1) | AR208080A1 (en) |
| AT (1) | AT351523B (en) |
| BE (1) | BE828001A (en) |
| CA (1) | CA1033747A (en) |
| CH (1) | CH605811A5 (en) |
| DE (1) | DE2515110A1 (en) |
| DK (1) | DK166475A (en) |
| ES (1) | ES436422A1 (en) |
| FI (1) | FI750867A (en) |
| FR (1) | FR2268017B1 (en) |
| GB (1) | GB1446301A (en) |
| HU (1) | HU173570B (en) |
| IE (1) | IE40915B1 (en) |
| IL (1) | IL47071A0 (en) |
| NL (1) | NL7504718A (en) |
| NO (1) | NO143626C (en) |
| SE (1) | SE7504507L (en) |
| SU (3) | SU637083A3 (en) |
| ZA (1) | ZA752255B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54119459A (en) * | 1978-03-08 | 1979-09-17 | Koba Tsuneyoshi | Antirheumatic |
| JPS5936245U (en) * | 1982-08-30 | 1984-03-07 | 日本電信電話株式会社 | Wafer vacuum suction device |
| FR2647447B1 (en) * | 1989-05-23 | 1991-08-23 | Rhone Poulenc Sante | PROCESS FOR THE PREPARATION OF (CHLORO-2 ETHYL) -1 METHYL-2 NITRO-5 IMIDAZOLE |
| WO2014030142A2 (en) * | 2012-08-24 | 2014-02-27 | Auckland Uniservices Limited | Nitroimidazole compounds and their use in cancer therapy |
-
1974
- 1974-04-19 CH CH545974A patent/CH605811A5/xx not_active IP Right Cessation
-
1975
- 1975-01-01 AR AR258173A patent/AR208080A1/en active
- 1975-03-24 FI FI750867A patent/FI750867A/fi not_active Application Discontinuation
- 1975-04-03 AT AT254975A patent/AT351523B/en not_active IP Right Cessation
- 1975-04-07 DE DE19752515110 patent/DE2515110A1/en not_active Withdrawn
- 1975-04-08 ES ES436422A patent/ES436422A1/en not_active Expired
- 1975-04-09 IE IE800/75A patent/IE40915B1/en unknown
- 1975-04-09 ZA ZA00752255A patent/ZA752255B/en unknown
- 1975-04-09 GB GB1451875A patent/GB1446301A/en not_active Expired
- 1975-04-11 IL IL47071A patent/IL47071A0/en unknown
- 1975-04-15 NO NO751323A patent/NO143626C/en unknown
- 1975-04-16 BE BE155460A patent/BE828001A/en unknown
- 1975-04-18 SE SE7504507A patent/SE7504507L/en unknown
- 1975-04-18 DK DK166475A patent/DK166475A/en not_active Application Discontinuation
- 1975-04-18 SU SU752127886A patent/SU637083A3/en active
- 1975-04-18 CA CA225,425A patent/CA1033747A/en not_active Expired
- 1975-04-18 FR FR7512225A patent/FR2268017B1/fr not_active Expired
- 1975-04-18 JP JP4735575A patent/JPS5314073B2/ja not_active Expired
- 1975-04-18 HU HU75CE1042A patent/HU173570B/en unknown
- 1975-04-21 NL NL7504718A patent/NL7504718A/en not_active Application Discontinuation
-
1976
- 1976-10-14 SU SU762409560A patent/SU671727A3/en active
- 1976-12-07 SU SU762426144A patent/SU659091A3/en active
-
1977
- 1977-10-14 JP JP52123404A patent/JPS5935400B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL47071A0 (en) | 1975-06-25 |
| FI750867A (en) | 1975-10-20 |
| GB1446301A (en) | 1976-08-18 |
| NO143626C (en) | 1981-03-18 |
| SE7504507L (en) | 1975-10-20 |
| SU637083A3 (en) | 1978-12-05 |
| CA1033747A (en) | 1978-06-27 |
| AT351523B (en) | 1979-07-25 |
| NO751323L (en) | 1975-10-21 |
| BE828001A (en) | 1975-08-18 |
| FR2268017B1 (en) | 1979-03-16 |
| ES436422A1 (en) | 1977-04-01 |
| ATA254975A (en) | 1979-01-15 |
| NL7504718A (en) | 1975-10-21 |
| JPS50148358A (en) | 1975-11-27 |
| ZA752255B (en) | 1976-02-25 |
| SU671727A3 (en) | 1979-06-30 |
| HU173570B (en) | 1979-06-28 |
| FR2268017A1 (en) | 1975-11-14 |
| IE40915B1 (en) | 1979-09-12 |
| SU659091A3 (en) | 1979-04-25 |
| DK166475A (en) | 1975-10-20 |
| JPS5387355A (en) | 1978-08-01 |
| JPS5935400B2 (en) | 1984-08-28 |
| DE2515110A1 (en) | 1975-10-23 |
| JPS5314073B2 (en) | 1978-05-15 |
| CH605811A5 (en) | 1978-10-13 |
| NO143626B (en) | 1980-12-08 |
| AR208080A1 (en) | 1976-11-30 |
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