IE39909B1 - Novel antibiotics and process for their preparation - Google Patents
Novel antibiotics and process for their preparationInfo
- Publication number
- IE39909B1 IE39909B1 IE1639/74A IE163974A IE39909B1 IE 39909 B1 IE39909 B1 IE 39909B1 IE 1639/74 A IE1639/74 A IE 1639/74A IE 163974 A IE163974 A IE 163974A IE 39909 B1 IE39909 B1 IE 39909B1
- Authority
- IE
- Ireland
- Prior art keywords
- hydrogen
- prepared
- hydrolysis
- hydroxy
- derivative
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 11
- 239000001257 hydrogen Substances 0.000 abstract 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 230000007062 hydrolysis Effects 0.000 abstract 4
- 238000006460 hydrolysis reaction Methods 0.000 abstract 4
- DTFAJAKTSMLKAT-JDCCYXBGSA-N 2-deoxystreptamine Chemical compound N[C@H]1C[C@@H](N)[C@H](O)[C@@H](O)[C@@H]1O DTFAJAKTSMLKAT-JDCCYXBGSA-N 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NCLVCCNBKRLETR-FBXFSONDSA-N (1s,3r,4r,6s)-4,6-diaminocyclohexane-1,3-diol Chemical compound N[C@H]1C[C@@H](N)[C@H](O)C[C@@H]1O NCLVCCNBKRLETR-FBXFSONDSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 101100234822 Caenorhabditis elegans ltd-1 gene Proteins 0.000 abstract 1
- 241000790917 Dioxys <bee> Species 0.000 abstract 1
- 241000218919 Micromonospora inyonensis Species 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- -1 hydroxy, amino Chemical group 0.000 abstract 1
- ZVVXVFDNCIMZHX-UHFFFAOYSA-N iodo-methyl-triphenyl-$l^{5}-phosphane Chemical compound C=1C=CC=CC=1P(I)(C=1C=CC=CC=1)(C)C1=CC=CC=C1 ZVVXVFDNCIMZHX-UHFFFAOYSA-N 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 230000001035 methylating effect Effects 0.000 abstract 1
- LYGJENNIWJXYER-UHFFFAOYSA-N nitromethane Chemical compound C[N+]([O-])=O LYGJENNIWJXYER-UHFFFAOYSA-N 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 150000002917 oxazolidines Chemical class 0.000 abstract 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38575173A | 1973-08-06 | 1973-08-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39909L IE39909L (en) | 1975-02-06 |
| IE39909B1 true IE39909B1 (en) | 1979-01-31 |
Family
ID=23522722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1639/74A IE39909B1 (en) | 1973-08-06 | 1974-08-01 | Novel antibiotics and process for their preparation |
Country Status (12)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1529376A (en) * | 1975-02-18 | 1978-10-18 | Sterling Drug Inc | Aminocyclitol antibiotics and processes therefor |
| US4171356A (en) * | 1976-10-28 | 1979-10-16 | Schering Corporation | 2-Unsubstituted derivatives of 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitois, methods for their use as antibacterial agents and compositions useful therefor |
| JPS59134691U (ja) * | 1983-02-28 | 1984-09-08 | トステム株式会社 | 防虫網付サツシ窓用換気装置 |
| JPS6248816U (enrdf_load_stackoverflow) * | 1985-09-17 | 1987-03-26 |
-
1974
- 1974-07-31 CH CH1059974A patent/CH606434A5/xx not_active IP Right Cessation
- 1974-08-01 NL NL7410364A patent/NL7410364A/xx not_active Application Discontinuation
- 1974-08-01 IT IT25836/74A patent/IT1043872B/it active
- 1974-08-01 SE SE7409945A patent/SE404375B/xx unknown
- 1974-08-01 GB GB33967/74A patent/GB1480374A/en not_active Expired
- 1974-08-01 ZA ZA00744939A patent/ZA744939B/xx unknown
- 1974-08-01 ZA ZA00744938A patent/ZA744938B/xx unknown
- 1974-08-01 FR FR7426816A patent/FR2240016B1/fr not_active Expired
- 1974-08-01 DE DE2437159A patent/DE2437159C2/de not_active Expired
- 1974-08-01 IE IE1639/74A patent/IE39909B1/xx unknown
- 1974-08-02 IL IL45387A patent/IL45387A/xx unknown
- 1974-08-02 JP JP8816474A patent/JPS562080B2/ja not_active Expired
- 1974-08-02 BE BE147232A patent/BE818429A/xx unknown
- 1974-08-02 JP JP49088162A patent/JPS5749199B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1043872B (it) | 1980-02-29 |
| DE2437159A1 (de) | 1975-02-20 |
| NL7410364A (nl) | 1975-02-10 |
| FR2240016A1 (enrdf_load_stackoverflow) | 1975-03-07 |
| JPS5749199B2 (enrdf_load_stackoverflow) | 1982-10-20 |
| GB1480374A (en) | 1977-07-20 |
| AU7194074A (en) | 1976-02-05 |
| CH606434A5 (enrdf_load_stackoverflow) | 1978-10-31 |
| IE39909L (en) | 1975-02-06 |
| JPS5047951A (enrdf_load_stackoverflow) | 1975-04-28 |
| ZA744938B (en) | 1975-08-27 |
| JPS562080B2 (enrdf_load_stackoverflow) | 1981-01-17 |
| JPS5042092A (enrdf_load_stackoverflow) | 1975-04-16 |
| FR2240016B1 (enrdf_load_stackoverflow) | 1977-06-03 |
| ZA744939B (en) | 1975-08-27 |
| SE404375B (sv) | 1978-10-02 |
| SE7409945L (enrdf_load_stackoverflow) | 1975-02-07 |
| IL45387A0 (en) | 1974-11-29 |
| BE818429A (fr) | 1975-02-03 |
| DE2437159C2 (de) | 1983-03-24 |
| IL45387A (en) | 1978-10-31 |
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